Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tracie Plant"'
Publikováno v:
Clinical Infection in Practice, Vol 21, Iss , Pp 100250- (2024)
Background: Lung infection by Scedosporium apiospermum in immunocompetent individuals is very rare. Case Report: We present a unique case of mediastinal granulomatous inflammatory lymphadenopathy in a diabetic and cirrhotic individual with a history
Externí odkaz:
https://doaj.org/article/0d79e2c01258467cb16ce8db10c26f46
Autor:
Konstadina Griva, Jan Stygall, Mark H Wilson, Daniel Martin, Denny Levett, Kay Mitchell, Monty Mythen, Hugh E Montgomery, Mike P Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi, Stanton P Newman, Caudwell Xtreme Everest Research Group
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174277 (2017)
The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300 m).A neuropsychological (NP) test
Externí odkaz:
https://doaj.org/article/638adf4514f441969483a33ab317fbb2
Autor:
Eleanor Maguire, Debbie McMillan, Tracie Plant, Lindsey Allan, Julie Mencnarowski, Colin Barrie, Melanie Mackean, Iain Phillips
Publikováno v:
Lung Cancer. 178:S72-S73
Autor:
Andrew J. M. Howden, Sarah R. Walmsley, Alex von Kriegsheim, Jens L. Hukelmann, Eilise M. Ryan, Rebecca S. Dickinson, Fiona Murphy, Gio Rodriguez Blanco, Bart Ghesquière, Patrícia Coelho, Doreen A. Cantrell, Emily R. Watts, Pranvera Sadiku, Robert Grecian, Ananda S. Mirchandani, Wesley Vermaelen, Tyler Morrison, Duncan Humphries, Tracie Plant, Moira K. B. Whyte, Andrew J. Finch
Publikováno v:
Watts, E R, Howden, A J M, Morrison, T, Sadiku, P, Hukelmann, J L, Von Kriegsheim, A, Ghesquière, B, Murphy, F, Mirchandani, A S, Humphries, D C, Grecian, R, Ryan, E M, Coelho, P, Rodriguez-blanco, G, Plant, T M, Dickinson, R S, Finch, A J, Vermaelen, W, Cantrell, D A, Whyte, M K B & Walmsley, S R 2021, ' Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism ', Journal of Clinical Investigation . https://doi.org/10.1172/JCI134073
Limiting dysfunctional neutrophilic inflammation while preserving effective immunity requires a better understanding of the processes that dictate neutrophil function in the tissues. Quantitative mass-spectrometry identified how inflammatory murine n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a5393e0379a24b90ce692f5f16f351
https://hdl.handle.net/20.500.11820/6ee67df8-79e3-477f-a412-02d6f22765b7
https://hdl.handle.net/20.500.11820/6ee67df8-79e3-477f-a412-02d6f22765b7
Autor:
Ailiang Zhang, Fiona Murphy, S Eamsamarng, Jenna L. Cash, Andrew J.W. Furley, Freek van Eeden, Tracie Plant, Moira K. B. Whyte, Emily R. Watts, Tyler Morrison, Leila Reyes, Felix Ellett, Jessie-May Morgan, Philip M. Elks, Patrícia Coelho, Stephen A. Renshaw, Ximena L. Raffo-Iraolagoitia, Ananda S. Mirchandani, Duncan Humphries, Manuel A. Sanchez-Garcia, Leo M. Carlin, Sarah R. Walmsley, Catherine A. Loynes
Publikováno v:
The Journal of Clinical Investigation
Plant, T, Eamsamarng, S, Sanchez-Garcia, M A, Reyes, L, Renshaw, S A, Coelho, P, Mirchandani, A S, Morgan, J-M, Ellett, F E, Morrison, T, Humphries, D, Watts, E R, Murphy, F, Raffo-Iraolagoitia, X L, Zhang, A, Cash, J L, Loynes, C, Elks, P M, Van Eeden, F, Carlin, L M, Furley, A J W, Whyte, M K B & Walmsley, S R 2020, ' Semaphorin 3F signaling actively retains neutrophils at sites of inflammation ', Journal of Clinical Investigation, vol. 130, no. 6, pp. 3221-3237 . https://doi.org/10.1172/JCI130834
Plant, T, Eamsamarng, S, Sanchez-Garcia, M A, Reyes, L, Renshaw, S A, Coelho, P, Mirchandani, A S, Morgan, J-M, Ellett, F E, Morrison, T, Humphries, D, Watts, E R, Murphy, F, Raffo-Iraolagoitia, X L, Zhang, A, Cash, J L, Loynes, C, Elks, P M, Van Eeden, F, Carlin, L M, Furley, A J W, Whyte, M K B & Walmsley, S R 2020, ' Semaphorin 3F signaling actively retains neutrophils at sites of inflammation ', Journal of Clinical Investigation, vol. 130, no. 6, pp. 3221-3237 . https://doi.org/10.1172/JCI130834
Neutrophilic inflammation is central to disease pathogenesis, for example, in chronic obstructive pulmonary disease, yet the mechanisms that retain neutrophils within tissues remain poorly understood. With emerging evidence that axon guidance factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4963bd1f4fcfae952a20c7a3ca638346
Autor:
Ajm Howden, Ananda S. Mirchandani, Patrícia Coelho, Rebecca S. Dickinson, Tracie Plant, A von Kriegsheim, Wesley Vermaelen, Fiona Murphy, Doreen A. Cantrell, Emily R. Watts, Andrew J. Finch, Pranvera Sadiku, Jens L. Hukelmann, Robert Grecian, Duncan Humphries, MK Whyte, Eilise M. Ryan, Sarah R. Walmsley, Bart Ghesquière
Publikováno v:
Fuelling the fire: inflammation and infection in lung disease.
Introduction and objectives Acute Respiratory Distress Syndrome (ARDS) is characterised by neutrophil driven alveolar and vascular injury. Alveolar damage is associated with worsening hypoxia and increased mortality. Specific therapies targeting neut
Autor:
Felix Ellett, Tracie Plant, Sarah R. Walmsley, S. Eamsamnarng, Ananda S. Mirchandani, MK Whyte, Leo M. Carlin, Fiona Murphy, Emily R. Watts, Jessie-May Morgan, Andrew J.W. Furley
Publikováno v:
BTS/BALR/BLF Early Career Investigators awards symposium.
Effective host responses to injury and infection require both rapid recruitment of neutrophils into tissues and timely inflammation resolution. Research currently focuses on initiation and resolution as distinct phases of inflammation and neutrophil
Autor:
Tracie Plant, Fiona Murphy, Sarah R. Walmsley, Paul Brennan, Moira K. B. Whyte, Alison Harris, Shonna Johnston, Imran Liaquat, Patrícia Coelho
Gliobalstomas (GBM) are the most prevalent type of malignant brain tumour with the median survival from diagnosis in the region of 6–9 months. GBM are both highly infiltrated with neutrophils and demonstrate a high degree of regional hypoxia. Recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516b77b4abf4f0da2a1ec5ddd9d0e909
https://europepmc.org/articles/PMC5791720/
https://europepmc.org/articles/PMC5791720/
Autor:
Peter Carmeliet, David Sammut, Bart Ghesquière, Kate E. McDonald, Alison Harris, Moira K. B. Whyte, Fiona Murphy, Joseph A Willson, A. A. Roger Thompson, Sarah R. Walmsley, Tracie Plant, Pranvera Sadiku, John Newell-Price, Eleni Daniel, Amy Lewis, Robert C. Jones, Brian G. Keevil, Rebecca S. Dickinson
Publikováno v:
Jones, R, McDonald, K E, Willson, J A, Ghesquiere, B, Sammut, D, Daniel, E, Harris, A J, Lewis, A, Thompson, A A R, Dickinson, R S, Plant, T, Murphy, F, Sadiku, P, Keevil, B G, Carmeliet, P, Whyte, M K B, Newell-Price, J & Walmsley, S R 2016, ' Mutations in Succinate Dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1alpha expression ', Blood, vol. 127, no. 21, pp. 2641-2644 . https://doi.org/10.1182/blood-2016-02-696922
To the editor: Neutrophils are unusual in their reliance on glycolysis to maintain their energy requirements[1][1] despite the presence of mitochondria and tricarboxylic acid (TCA) cycle intermediaries.[2][2] This metabolic adaptation is thought in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880d4074482d889a79416bb79c747e8c
https://www.pure.ed.ac.uk/ws/files/28438823/2641.full.pdf
https://www.pure.ed.ac.uk/ws/files/28438823/2641.full.pdf
Autor:
Tracie Plant, Golnar Aref-Adib
Publikováno v:
British Journal of Hospital Medicine. 69:348-352
Over 40 million people travel to high altitude for both work and pleasure each year, and all of them are at risk of the acute effects of hypoxia. This article reviews the prevention, diagnostic features and treatments of these illnesses.