Výsledky vyhledávání - "Tracie E. Bunton"

Regulation of left-right patterning in mice by growth/differentiation factor-1

Autor: Se-Jin Lee, Christopher Rankin, Ann M. Lawler, Tracie E. Bunton

Publikováno v: Nature Genetics. 24:262-265

The transforming growth factor-beta (TGF-beta) superfamily encompasses a large group of structurally related polypeptides that are capable of regulating cell growth and differentiation in a wide range of embryonic and adult tissues. Growth/differenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed3b88dedda323a6c2b4ea92d1bdebc
https://doi.org/10.1038/73472

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Targetting of the gene encoding fibrillin–1 recapitulates the vascular aspect of Marfan syndrome

Autor: Nancy Jensen Biery, Lygia da Veiga Pereira, Lynn Y. Sakai, Jenny Tian, Harry C. Dietz, Sui Ying Lee, Tracie E. Bunton, Konstantinos Andrikopoulos, Douglas R. Keene, Dieter P. Reinhardt, Francesco Ramirez, Robert N. Ono

Publikováno v: Nature Genetics. 17:218-222

Aortic aneurysm and dissection account for about 2% of all deaths in industrialized countries; they are also components of several genetic diseases, including Marfan syndrome (MFS). The vascular phenotype of MFS results from mutations in fibrillin-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bc00da88b3aa142f049abceb906ae0
https://doi.org/10.1038/ng1097-218

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Review Article: Experimental Chemical Carcinogenesis in Fish

Autor: Tracie E. Bunton

Publikováno v: Toxicologic Pathology. 24:603-618

Tracie Eileen Bunton received a DVM degree from Michigan State University in 1977. After practicing small animal medicine for a year, she completed a combined Comparative Pathology residency/Ph.D. program in 1982 at the University of California at Da

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https://doi.org/10.1177/019262339602400511

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Reactivity of Tissue-Specific Antigens in N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Neoplasms and Normal Tissues from Medaka (Oryzias latipes)*1

Autor: Tracie E. Bunton, Marilyn J. Wolfe

Publikováno v: Toxicologic Pathology. 24:331-338

To further characterize the distribution of tissue-specific antigens in fish neoplasms, juvenile medaka were exposed to 30 mg/L of N-methyl- N'-nitro- N-nitrosoguanidine (MNNG) for 1 hr and allowed to grow out for up to 16 mo. Using a streptavidin pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::291e61dcbb3f3739b15b466f801e07d4
https://doi.org/10.1177/019262339602400309

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N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Neoplasms in Medaka (Oryzias latipes)*1

Autor: Tracie E. Bunton, Marilyn J. Wolfe

Publikováno v: Toxicologic Pathology. 24:323-330

To test the sensitivity of the small fish species Oryzias latipes to the direct-acting carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), medaka were exposed at 15 days of age to 30 mg/L for 1 hr and followed for up to 16 mo. One hundred neoplas

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https://doi.org/10.1177/019262339602400308

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Expression of actin and desmin in experimentally induced hepatic lesions and neoplasms from medaka (Oryzias latipes)

Autor: Tracie E. Bunton

Publikováno v: Carcinogenesis. 16:1059-1063

Proliferation of stromal cells is a common occurrence in experimentally induced hepatocarcinogenesis in fish. However, the role of these cells in fish hepatic injury and neoplasia is unknown. To better understand the biology of the cells comprising t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8553fe326ff59ce6d249bfba2c573e98
https://doi.org/10.1093/carcin/16.5.1059

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Extrahepatic tissue copper concentrations in white perch with hepatic copper storage

Autor: John M. Frazier, Tracie E. Bunton

Publikováno v: Journal of Fish Biology. 45:627-640

Hepatic copper storage in man (Wilson's disease), Bedtington and West Highland white terriers, and white perch (Morone americana) is characterized by the progressive accumulation of copper in hepatic lysosomes bound to cytoprotective metallothionein.

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https://doi.org/10.1111/j.1095-8649.1994.tb00929.x

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Ultrastructure of hepatic hemangiopericytoma in the medaka (Oryzias latipes)

Autor: Tracie E. Bunton

Publikováno v: Experimental and Molecular Pathology. 54:87-98

The histologic and ultrastructural features of hepatic hemangiopericytoma from a medaka (Oryzias latipes) exposed for 48 hr to 400 mg/liter of diethylnitrosamine at 14 days of age are described. The predominant histologic pattern was of spindle-shape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95159544d69769d8dd9f8dc151d1f6d
https://doi.org/10.1016/0014-4800(91)90022-p

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Hepatopathology of Diethylnitrosamine in the Medaka (Oryzias latipes) Following Short-Term Exposure

Autor: Tracie E. Bunton

Publikováno v: Toxicologic Pathology. 18:313-323

The effect of short-term exposure (48 hr) of 14-day-old medaka (Oryzias latipes) to diethylnitrosamine (DEN) was tested on 4 groups of fish at 0, 100, 200, and 400 mg/L, with interim sacrifices of up to 6 months post exposure. Many of the lesions see

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https://doi.org/10.1177/019262339001800210

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