Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tracie Cheng"'
Autor:
Sharmin Aktar, Sujani Gamage, Tracie Cheng, Nahal Pakneshan, Cu Lu, Farhadul Islam, Vinod Gopalan, Alfred Lam
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 5; Pages: 5051
Information regarding genetic alterations of driver cancer genes in circulating tumour cells (CTCs) and their surrounding immune microenvironment nowadays can be employed as a real-time monitoring platform for translational applications such as patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e962e3f2b46938ed77d91b72dbf0be9
Autor:
Tracie Cheng, Sujani Madhurika Kodagoda Gamage, Dinu Hewage, Cu-Tai Lu, Sharmin Aktar, Vinod Gopalan, Alfred King-yin Lam
Publikováno v:
Human Pathology. 122:50-59
The relationship between red and processed meat and its risk toward colorectal carcinoma (CRC) is not fully explored in literature. Polycyclic aromatic hydrocarbons (PAHs) are procarcinogenic molecules that are ingested with meat cooked at high tempe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f61546952a14b7e7d3ad1d6814e0ba2
https://doi.org/10.1016/j.humpath.2022.02.001
https://doi.org/10.1016/j.humpath.2022.02.001
Autor:
S. M. K. Gamage, Sharmin Aktar, Farhadul Islam, Cu T. Lu, Lakal Dissabandara, Katherine Ting-Wei Lee, Chamath D. Ranaweera, Vinod Gopalan, Tracie Cheng, Alfred King-Yin Lam
Publikováno v:
Human Pathology. 117:9-30
Summary The study aimed to screen mutation of human homeostatic iron regulator (HFE) in colorectal carcinoma (CRC) and detect their associations with clinicopathological parameters. Expression of HFE was determined by quantitative polymerase chain re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c2b35f072144e3507ecd7d25c360b7
https://doi.org/10.1016/j.humpath.2021.07.013
https://doi.org/10.1016/j.humpath.2021.07.013
Autor:
Tracie Cheng, Sujani Madhurika Kodagoda Gamage, Cu-Tai Lu, Sharmin Aktar, Vinod Gopalan, Alfred King-yin Lam
Publikováno v:
Pathology, research and practice. 231
CYP1A1 enzyme is integral to the biotransformation of polycyclic aromatic hydrocarbons to carcinogenic compounds. This study aimed to screen mutations in exon 7 (ex7) of CYP1A1 and investigate its clinicopathological correlations in fresh tissue samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd029ce0bb163f1268de314d846e427
https://pubmed.ncbi.nlm.nih.gov/35180652
https://pubmed.ncbi.nlm.nih.gov/35180652
Publikováno v:
Critical reviews in oncology/hematology. 168
Polycyclic aromatic hydrocarbon (PAHs) are molecules that contaminate meat products during the high-temperature cooking of meat. This study reviewed the pathogenic roles of meat derived polycyclic aromatic hydrocarbons in the carcinogenesis of colore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4b5f316d747f759c081752f8deeec7
https://pubmed.ncbi.nlm.nih.gov/34748942
https://pubmed.ncbi.nlm.nih.gov/34748942
Autor:
Sujani M.K. Gamage, Sachith Nanayakkara, Lilian Macfarlane, Dinu Hewage, Tracie Cheng, Sharmin Aktar, Cu Tai Lu, Lakal Dissabandara, Farhadul Islam, Alfred King-Yin Lam, Vinod Gopalan
Publikováno v:
Pathology - Research and Practice. 233:153885
Literature suggests Heme oxygenase (HO) system to be a double-edged sword which can promote both cytoprotection as well as carcinogenicity. The aim of this study was to investigate the role of heme in HO-1 and HO-2 induced colorectal carcinogenesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b558f59b52fe2d17af1e934c80ae5
https://doi.org/10.1016/j.prp.2022.153885
https://doi.org/10.1016/j.prp.2022.153885
Publikováno v:
Cancer genetics.
Background The purposes of the study were to enumerate and characterise the circulating tumour cell (CTC) and cluster/micro-emboli (CTM) in blood from patients with colorectal carcinoma (CRC) as well as to investigate their clinical relevance. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4bdf9d48fc6d1ebeb58fcd807d4c79
https://pubmed.ncbi.nlm.nih.gov/33610860
https://pubmed.ncbi.nlm.nih.gov/33610860
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10959, p 10959 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10959, p 10959 (2021)
Polycyclic aromatic hydrocarbons (PAHs) are commonly ingested via meat and are produced from high-temperature cooking of meat. Some of these PAHs have potential roles in carcinogenesis of colorectal cancer (CRC). We aimed to investigate PAH concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297c4ddd5cdc1aaeba70d87f199494fa
https://doi.org/10.3390/ijms222010959
https://doi.org/10.3390/ijms222010959
Autor:
S. M. K. Gamage, Vinod Gopalan, Lakal Dissabandara, Katherine Ting-Wei Lee, Alfred King-Yin Lam, Tracie Cheng
Publikováno v:
Pathology - Research and Practice. 224:153530
Heme, a molecule abundant in red meat, is assumed to exert carcinogenic effects on normal colonic cells and tumour suppressive effects on cancer cells, though the hypothesis has not been explicitly proven yet. The present study aims to investigate he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b0e169be5ea08c5d07b2b7c94e385c
https://doi.org/10.1016/j.prp.2021.153530
https://doi.org/10.1016/j.prp.2021.153530
Autor:
Marco Matos, Cu-Tai Lu, Faysal-Bin Hamid, Alfred King-Yin Lam, Vinod Gopalan, Farhad Islam, Tracie Cheng
Publikováno v:
Cancer Research. 80:5367-5367
The number of circulating tumor cells (CTCs) hase been found as a promising predictive and diagnostic biomarker of colorectal cancer (CRC). The purpose of the study was to enumerate and characterize CTCs from the CRC patients and evaluate the correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485dbb9516ea615ab80c5e6b8657a915
https://doi.org/10.1158/1538-7445.am2020-5367
https://doi.org/10.1158/1538-7445.am2020-5367