Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Traci Legere"'
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Traci Legere, Pradeep B. J. Reddy, Korey A. Walter, Bali Pulendran, Prabhu S. Arunachalam, Shankar Subramaniam, Florian Wimmers, Madeleine K D Scott, Celia C. LaBranche, Bertrand Z. Yeung, John P. Vasilakos, Venkata S. Bollimpelli, Samantha L. Burton, Sailaja Gangadhara, Sudhir Pai Kasturi, Shakti Gupta, Cynthia A. Derdeyn, Caroline Petitdemange, Pamela A. Kozlowski, David C. Montefiori, Tiffany M. Styles, Thomas J. Ketas, John P. Moore, Chil Yong Kang, Rama Rao Amara, Eric Hunter, George M. Shaw, Purvesh Khatri, Mark A. Tomai, Anthony Tsai, David Masopust, Vineet Joag, Clare F. Quarnstrom, Tysheena P. Charles
Publikováno v:
Nature Medicine
Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to
Autor:
Traci Legere, Richard Green, James R. Bowen, Courtney Wilkins, Lynette S. Chea, Sunil Kannanganat, Tianwei Yu, Vijayakumar Velu, Jean Chang, Michelle A. Lifton, Venkateswarlu Chamcha, Sampa Santra, Pradeep B. J. Reddy, Cynthia A. Derdeyn, Pamela A. Kozlowski, Francois Villinger, Guido Silvestri, Eric Hunter, Rama Rao Amara, Sailaja Gangadhara, Lakshmi Chennareddi, Mehul S. Suthar, G. Lynn Law, Michael Gale
Publikováno v:
Sci Transl Med
Activated CD4 T cells are a major target of HIV infection. Results from the STEP HIV vaccine trial highlighted a potential role for total activated CD4 T cells in promoting HIV acquisition. However, the influence of vaccine insert-specific CD4 T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138140c4eea73b27c368fc0bd603aef7
https://europepmc.org/articles/PMC7227795/
https://europepmc.org/articles/PMC7227795/
Autor:
Bali Pulendran, Traci Legere, Tiffany M. Styles, Peter T. Hraber, Lori M Spicer, Pradeep B. J. Reddy, Tysheena P. Charles, Cynthia A. Derdeyn, Sailaja Gangadhara, Vijayakumar Velu, Sudhir Pai Kasturi, Eric Hunter, Samantha L. Burton, Rama Rao Amara
Publikováno v:
Journal of Virology. 93
The goals of preclinical HIV vaccine studies in nonhuman primates are to develop and test different approaches for their ability to generate protective immunity. Here, we compared the impact of 7 different vaccine modalities, all expressing the HIV-1
Autor:
John P. Vasilakos, Rafiq Nabi, Dan H. Barouch, Yevgeniy Kovalenkov, Sudhir Pai Kasturi, Pamela A. Kozlowski, Traci Legere, Bali Pulendran, Jonathan W. Yewdell, David C. Montefiori, Jens Wrammert, James S. Gibbs, Parin Patel, Lori M. Spicer, Mark A. Tomai, Pradeep B. J. Reddy, Eric Hunter, Barton F. Haynes, C. Yong Kang, Clare F. Quarnstrom, David Masopust, Caroline Petitdemange, Cynthia A. Derdeyn, Celia C. LaBranche, Francois Villinger, Rama Rao Amara
Publikováno v:
JCI insight. 4(4)
Antibodies and cytotoxic T cells represent 2 arms of host defense against pathogens. We hypothesized that vaccines that induce both high-magnitude CD8(+) T cell responses and antibody responses might confer enhanced protection against HIV. To test th
Autor:
Bali Pulendran, Sudhir Pai Kasturi, Yevgeniy Kovalenkov, Jens Wrammert, Zarpheen S. Jinnah, Francois Villinger, Ata Ur Rasheed, Eduardo Lani Volpe da Silveira, Patryce Yeiser, Traci Legere
Publikováno v:
Journal of Immunological Methods. 416:69-83
Over 100 broadly neutralizing antibodies have been isolated from a minority of HIV infected patients, but the steps leading to the selection of plasma cells producing such antibodies remain incompletely understood, hampering the development of vaccin
Autor:
Bali Pulendran, Steven E. Bosinger, Sudhir Pai Kasturi, Eric Hunter, Mathew J. Johnson, Helder I. Nakaya, Xuemin Chen, Colin Havenar-Daughton, Pedro de Sá Tavares Russo, Rafiq Nabi, Paul Spearman, Zarpheen Jinnah Sher, Francois Villinger, Katie M. Kilgore, Jens Wrammert, Traci Legere, Yevgeniy Kovalenkov, Matheus Carvalho Bürger, Shane Crotty, Eduardo Lani Volpe da Silveira, Pamela A. Kozlowski, Rama Rao Amara, Cynthia A. Derdeyn, Samantha L. Burton, Mathew Pham
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Our previous work has shown that antigens adjuvanted with ligands specific for Toll-like receptor 4 (TLR4) and TLR7/8 encapsulated in poly(lactic-co-glycolic) acid (PLGA)-based nanoparticles (NPs) induce robust and durable immune responses in mice an