Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Traci A. Lee"'
Autor:
Traci A. Lee, David J. Eide, Erin Weisenhorn, Janet Taggart, Jason D. Russell, Joshua J. Coon, Zhiyuan Yao, Michael D. Bucci, Spencer A. Haws, Daniel J. Klionsky, Molly Gannon, Ginelle R. Zimmerman
Publikováno v:
Genetics. 208:1115-1130
The Zap1 transcription factor of Saccharomyces cerevisiae is a key regulator in the genomic responses to zinc deficiency. Among the genes regulated by Zap1 during zinc deficiency is the autophagy-related gene ATG41. Here, we report that Atg41 is requ
Publikováno v:
Molecular Biology of the Cell
To examine how target gene expression is coordinated among members of a transcription factor family, a simple two-member family (Met31 and Met32) that is essential for regulating sulfur metabolism in budding yeast is examined using both transcription
Autor:
Traci A. Lee, Olivia Ho-Shing, David Botstein, R. Scott McIsaac, Allegra A. Petti, Sanford J. Silverman, Mark J. Hickman
Publikováno v:
Molecular Biology of the Cell
The sulfur assimilation and phospholipid biosynthesis pathways interact metabolically and transcriptionally. Genetic analysis, genome-wide sequencing, and expression microarrays show that regulators of these pathways, Met4p and Opi1p, control cellula
Autor:
Dominique Thomas, Paul Jorgensen, Traci A. Lee, Caroline Peyraud, Andrew L. Bognar, Mike Tyers
Publikováno v:
Molecular Biology of the Cell
Loss of Met31 and Met32 abolishes all Met4-activated transcription, while only certain target genes, such as sulfate assimilation genes, depend on Cbf1 and Met28 for expression. Unlike Met4 and the other cofactors, Cbf1 remains promoter-bound under i
Publikováno v:
Molecular Cell. 10:69-80
The ubiquitin system has been recently implicated in various aspects of transcriptional regulation, including proteasome-dependent degradation of transcriptional activators. In yeast, the activator Met4 is inhibited by the SCF Met30 ubiquitin ligase,
Autor:
Traci J Lee, LeAnne Kennedy
Publikováno v:
Annals of Pharmacotherapy. 34:377-381
OBJECTIVE: To evaluate the efficacy of tacrolimus for prevention of graft-versus-host disease (GVHD) in patients receiving allogeneic bone marrow transplants. DATA SOURCES: Published literature was identified through MEDLINE (January 1990–December
Autor:
Peggy Baudouin-Cornu, Dominique Thomas, Patrick Zarzov, Astrid Rouillon, Traci A Lee, Régine Barbey, Mike Tyers
Publikováno v:
The EMBO journal. 24(3)
Activity of the Met4 transcription factor is antagonized by the SCF(Met30) ubiquitin ligase by degradation-dependent and degradation-independent mechanisms, in minimal and rich nutrient conditions, respectively. In this study, we show that the heavy