Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tracey Tackaberry"'
Autor:
Jing Zhang, James D. Young, Tracey Tackaberry, Carol E. Cass, Delores Mowles, Thach Lang, Blake Tomkinson, Marilyn L Clarke, Vijaya L. Damaraju, Kyla M. Smith
Publikováno v:
Molecular Pharmacology. 70:303-310
4'-Thio-beta-D-arabinofuranosyl cytosine (TaraC) is in phase I development for treatment of cancer. In human equilibrative nucleoside transporter (hENT) 1-containing CEM cells, initial rates of uptake (10 microM; picomoles per microliter of cell wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda5bf1447c84198ea60c4d86d9792b0
https://doi.org/10.1124/mol.105.021543
https://doi.org/10.1124/mol.105.021543
Autor:
Jing Zhang, Tracey Tackaberry, Carol E. Cass, Taylor Raborn, Gerry Barron, Stephen A. Baldwin, James D. Young, Mabel W.L. Ritzel
Publikováno v:
Biochemical Journal. 394:389-398
hCNT3 (human concentrative nucleoside transporter 3) is a nucleoside–sodium symporter that transports a broad range of naturally occurring purine and pyrimidine nucleosides as well as anticancer nucleoside drugs. To understand its uridine binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510505b02e8ca55a40c1cd7675ebb8aa
https://doi.org/10.1042/bj20051476
https://doi.org/10.1042/bj20051476
Autor:
Jing Zhang, Carol E. Cass, Ireneusz Nowak, Stephen A. Baldwin, Edward Karpinski, Lars P. C. Nielsen, Kyla M. Smith, Morris J. Robins, James D. Young, Tracey Tackaberry, Frank Visser
Publikováno v:
Molecular Pharmacology. 68:830-839
Human concentrative nucleoside transporters 1, 2, and 3 (hCNT1, hCNT2, and hCNT3) exhibit different functional characteristics, and a better understanding of their permeant selectivities is critical for development of nucleoside analog drugs with opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5bf00b6e44e531c3dda9227ed366ff
https://doi.org/10.1124/mol.105.012187
https://doi.org/10.1124/mol.105.012187
Autor:
Vijaya L. Damaraju, Morris J. Robins, Carol E. Cass, Geraldine Barron, James D. Young, Tracey Tackaberry, Yunshan Peng, Delores Mowles
Publikováno v:
Journal of medicinal chemistry. 53(16)
5'-S-(2-aminoethyl)-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), 5'-S-(2-acetamidoethyl)-6-N-[(4-substituted)benzyl]-5'-thioadenosine analogues, 5'-S-[2-(6-aminohexanamido)]ethyl-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAHENTA), and related compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374033ea5144cf5ea36e1653c8aa2888
https://pubmed.ncbi.nlm.nih.gov/20718495
https://pubmed.ncbi.nlm.nih.gov/20718495
Autor:
James D. Young, Tracey Tackaberry, Frank Visser, Robert J. Paproski, Carol E. Cass, Jing Zhang, Vijaya L. Damaraju, Stephen A. Baldwin
Publikováno v:
The Biochemical journal. 414(2)
hENT1 (human equilibrative nucleoside transporter 1) is inhibited by nanomolar concentrations of various structurally distinct coronary vasodilator drugs, including dipyridamole, dilazep, draflazine, soluflazine and NBMPR (nitrobenzylmercaptopurine r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b8fb95fef343a0c49575415c23995c
https://pubmed.ncbi.nlm.nih.gov/18462193
https://pubmed.ncbi.nlm.nih.gov/18462193
Autor:
Frank Visser, James D. Young, Stephen A. Baldwin, Tracey Tackaberry, Carol E. Cass, Yunshan Peng, Morris J. Robins, Vijaya L. Damaraju, Lijie Sun
Publikováno v:
The Journal of biological chemistry. 282(19)
Equilibrative nucleoside transporters (ENTs) are important for the metabolic salvage of nucleosides and the cellular uptake of antineoplastic and antiviral nucleoside analogs. Human equilibrative nucleoside transporter 1 (hENT1) is inhibited by nanom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f277988224790044881bc644c236ebc8
https://pubmed.ncbi.nlm.nih.gov/17379602
https://pubmed.ncbi.nlm.nih.gov/17379602
Autor:
Xuejun Sun, Tracey Tackaberry, Carol E. Cass, Stephen A. Baldwin, Jing Zhang, Melissa D. Slugoski, Lars P. C. Nielsen, Pat Carpenter, Kyla M. Smith, Morris J. Robins, Ireneusz Nowak, James D. Young
Publikováno v:
The Journal of biological chemistry. 281(38)
The uptake of Urd into the yeast Saccharomyces cerevisiae is mediated by Fui1p, a Urd-specific nucleoside transporter encoded by the FUI1 gene and a member of the yeast Fur permease family, which also includes the uracil, allantoin, and thiamine perm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af50e32d224e369e134452b215e0f64c
https://pubmed.ncbi.nlm.nih.gov/16854981
https://pubmed.ncbi.nlm.nih.gov/16854981
Autor:
Sylvia Y.M. Yao, Thach Lang, Mark F. Vickers, Tracey Tackaberry, Karen M. King, James D. Young, Vijaya L. Damaraju, Delores Mowles, Amy M. L. Ng, Carol E. Cass
Publikováno v:
Molecular pharmacology. 69(1)
2-Chloro-9-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)adenine (Cl-F-ara-A, clofarabine), a purine nucleoside analog with structural similarity to 2-chloro-2'-deoxyadenosine (Cl-dAdo, cladribine) and 9-beta-d-arabinofuranosyl-2-fluoroadenine (F-ara-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c2f28c76c636fb81bfa83c03d878c0
https://pubmed.ncbi.nlm.nih.gov/16234483
https://pubmed.ncbi.nlm.nih.gov/16234483
Autor:
Frank Visser, Sambasivarao Damaraju, Mabel W.L. Ritzel, Jing Zhang, Stephen A. Baldwin, Jennifer Dufour, Melissa D. Slugoski, James D. Young, Carol E. Cass, Tracey Tackaberry, Kyla M. Smith
Publikováno v:
Pharmacogenetics and genomics. 15(3)
Human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), which mediates transport of purine and pyrimidine nucleosides and a variety of antiviral and anticancer nucleoside drugs, was investigated to determine if there are single nucleotide poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca87e67b3d0ca0f621b41eacdb490ce0
https://pubmed.ncbi.nlm.nih.gov/15861042
https://pubmed.ncbi.nlm.nih.gov/15861042
Autor:
Mark F. Vickers, James D. Young, Stephen A. Baldwin, Lars P. C. Nielsen, Frank Visser, Jing Zhang, Ireneusz Nowak, Carol E. Cass, Morris J. Robins, Tracey Tackaberry
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 23(1-2)
The sugar moiety of nucleosides has been shown to play a major role in permeant-transporter interaction with human equilibrative nucleoside transporters 1 and 2 (hENT1 and hENT2). To better understand the structural requirements for interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f91aa65550ecad0859a833088fcbc2b
https://pubmed.ncbi.nlm.nih.gov/15043160
https://pubmed.ncbi.nlm.nih.gov/15043160