Výsledky vyhledávání - "Tracey Sciuto"

Akademický článek

A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

Autor: Lei Yuan, Gary C. Chan, David Beeler, Lauren Janes, Katherine C. Spokes, Harita Dharaneeswaran, Anahita Mojiri, William J. Adams, Tracey Sciuto, Guillermo Garcia-Cardeña, Grietje Molema, Peter M. Kang, Nadia Jahroudi, Philip A. Marsden, Ann Dvorak, Erzsébet Ravasz Regan, William C. Aird

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)

Spontaneous phenotypic heterogeneity confers a population-level advantage to cells that are exposed to fluctuating environments. Here the authors show that the endothelium of some organs displays a dynamic mosaicism in expression of Von Willebrand fa

Externí odkaz: https://doaj.org/article/6ed9333a2a8b469cb9f3182d7d55819d

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Supplementary Table 2 from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Autor: Carmelo Nucera, S. Ananth Karumanchi, Jack Lawler, Joanne E. Murphy-Ullrich, Manoj Bhasin, Tracey Sciuto, Ann M. Dvorak, John Clohessy, Jennifer N. Sims, Soumya Ullas, Danica M. Vodopivec, Zeus A. Antonello, Swati S. Bhasin, Peter M. Sadow, Agnes S. Lo, Alessandro Prete

Suppl. Table 2. Log2 Fold Changes (FC) of some genes differentially expressed in BRAFV600E-PTC vs BRAFWT-PTC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857998e7451daf5dbd94d7245bc3c7b2
https://doi.org/10.1158/1078-0432.22469777

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Supplementary Figures 1-12 Legends from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Supplementary Figures 1-12 Legends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416f160f22d76021a94acdcf62a2a40e
https://doi.org/10.1158/1078-0432.22469789.v1

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Supplementary Methods from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Supplementary Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77446f1c9534207530025f18449a7fec
https://doi.org/10.1158/1078-0432.22469783

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Supplementary Table 3 from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Suppl. Table 3. Log2 Fold Changes (FC) of some genes differentially expressed in PTC with BRAFV600E and hTERT mutation vs BRAFV600E-PTC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33835eccc49b39c953e2ea0294518de1
https://doi.org/10.1158/1078-0432.22469774

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Supplementary Figures 1-12 from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Suppl. Figure 1 Drug dose-effect analysis in BRAFWT/V600E-KTC1 cells Suppl.Figure 2 Dose-effect analysis of vemurafenib and sorafenib on pericyte viability. Suppl. Figure 3 BRAFWT/WT-TPC1 cells viability assay. Suppl. Figure 4 ELISA analysis of cytok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1911b63b831cf45857804aa467025a69
https://doi.org/10.1158/1078-0432.22469786.v1

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Data from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Purpose:The BRAFV600E oncogene modulates the papillary thyroid carcinoma (PTC) microenvironment, in which pericytes are critical regulators of tyrosine-kinase (TK)-dependent signaling pathways. Although BRAFV600E and TK inhibitors are available, thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6582d75607d5dd614744ccf4dccf998c
https://doi.org/10.1158/1078-0432.c.6527339

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Supplementary Table 1 from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Supplementary Table 1 Antibodies list and experimental conditions for immunohistochemistry (IHC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6fccfbdc5a4e2850379fe59b6f615f
https://doi.org/10.1158/1078-0432.22469780

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Supplementary Table 4 from Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis

Suppl. Table 4. Log2 Fold Changes (FC) of some genes differentially expressed in PTC wih BRAFV600E and hTERT mutation vs BRAFWT-PTC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cffbd6fd4fc0885ba87ed10f2f99a8c
https://doi.org/10.1158/1078-0432.22469771

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