Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tracey M. Doyle"'
Autor:
Changgui Li, Tracey M. Doyle, Aeron C. Hurt, Anwar M. Hashem, Junzhi Wang, Runtao He, Xuguang Li, Doris Bucher, Terry D. Cyr, Yi-Min She, Earl G. Brown, Aaron Farnsworth, Gary Van Domselaar
Publikováno v:
Biochemical and Biophysical Research Communications. 441:226-229
All influenza viral neuraminidases (NA) of both type A and B viruses have only one universally conserved sequence located between amino acids 222-230. A monoclonal antibody against this region has been previously reported to provide broad inhibition
Autor:
Anwar M. Hashem, Aaron Farnsworth, Earl G. Brown, Tracey M. Doyle, Runtao He, Gary Van Domselaar, Bozena Jaentschke, Xuguang Li, Nicole E. Forbes, Junzhi Wang, Changgui Li
Publikováno v:
Journal of Biological Chemistry. 288:18283-18289
The only universally conserved sequence among all influenza A viral neuraminidases is located between amino acids 222 and 230. However, the potential roles of these amino acids remain largely unknown. Through an array of experimental approaches inclu
Autor:
Gary Van Domselaar, Changgui Li, Aaron Farnsworth, Anwar M. Hashem, Runtao He, Xuguang Li, Tracey M. Doyle, Junzhi Wang
Publikováno v:
Current Bioinformatics. 6:415-426
Publikováno v:
European Respiratory Journal. 38:679-687
Asthmatic responses are associated with the lung homing of bone marrow (BM)-derived progenitors implicated as effectors of disease pathology. Studies have shown that increases in lung extracted vascular endothelial progenitor cells (VEPCs) correlate
Autor:
Aeron C. Hurt, Earl G. Brown, Runtao He, Doris Bucher, Terry D. Cyr, Xuguang Li, Changgui Li, Tracey M. Doyle, Junzhi Wang, Anwar M. Hashem, Aaron Farnsworth, Gary Van Domselaar
Publikováno v:
BMC Genomics
BackgroundHemagglutinin (HA) and neuraminidase (NA) are thetwo major surface glycoproteins of influenza viruses andthe main targets of vaccine-induced antibodies (Abs).While several broadly neutralizing Abs targeting con-served epitopes in diverse HA
Autor:
Gary Van Domselaar, Louise Larocque, Junzhi Wang, Earl G. Brown, Aaron Farnsworth, Changgui Li, Terry D. Cyr, Tracey M. Doyle, Aeron C. Hurt, Anwar M. Hashem, Xuguang Li, Daryl G.S. Smith, Runtao He
Publikováno v:
Antiviral research. 100(2)
The only universally conserved sequence amongst all influenza A viral neuraminidase (NA) is located between amino acids 222-230 and plays crucial roles in viral replication. However, it remained unclear as to whether this universal epitope is exposed
Autor:
Runtao He, Caroline Gravel, Anwar M. Hashem, Tracey M. Doyle, Bozena Jaentschke, Xuguang Li, Monika Tocchi, Michael Rosu-Myles
Publikováno v:
Human vaccinesimmunotherapeutics. 8(4)
Current influenza vaccines mainly induce strain-specific neutralizing antibodies and need to be updated each year, resulting in significant burdens on vaccine manufacturers and regulatory agencies. Genetic immunization strategies based on the highly
Autor:
Tracey M. Doyle, Sean (Xuguang) Li
Publikováno v:
Journal of Virology & Antiviral Research.
Alternative Roles of Neuraminidase in Influenza a Viral Propagation Influenza A is an envelope virus containing a segmented negative RNA genome. The viral envelope has two major surface glycoproteins, Hemagglutinin (HA) and Neuraminidase (NA) of whic
Publikováno v:
D22. MODULATORS OF INFLAMMATORY PATHWAYS IN AIRWAY DISEASE.
Autor:
Jennifer V. Thomson, Paul Newbold, Tracey M. Doyle, Martyn Foster, Karen Howie, Roma Sehmi, Gail M. Gauvreau, Paul M. O'Byrne, MyLinh Duong, Richard I. Craggs, Irene Babirad, Adriana Catalli
Publikováno v:
The Journal of allergy and clinical immunology. 122(4)
Background Mobilization of hemopoietic progenitor cells from the bone marrow (BM) is a feature of inflammatory asthmatic responses. Understanding the mechanisms regulating progenitor cell mobilization and trafficking to the peripheral circulation mig