Metformin Improves Insulin Signaling in Obese Rats via Reduced IKKβ Action in a Fiber-Type Specific Manner

Autor: Benjamin T. Bikman, Donghai Zheng, Daniel A. Kane, Ethan J. Anderson, Tracey L. Woodlief, Jesse W. Price, G. Lynis Dohm, P. Darrell Neufer, Ronald N. Cortright

Publikováno v: Journal of Obesity, Vol 2010 (2010)

Metformin is a widely used insulin-sensitizing drug, though its mechanisms are not fully understood. Metformin has been shown to activate AMPK in skeletal muscle; however, its effects on the inhibitor of κB kinaseβ (IKKβ) in this same tissue are u

Externí odkaz: https://doaj.org/article/eb4e80b5269549fa9d73084b9c3798aa

Immunotoxicity of Per- and Polyfluoroalkyl Substances: Insights into Short-Chain PFAS Exposure

Autor: Jamie C. DeWitt, Qing Hu, Samuel Vance, Tracey L. Woodlief

Publikováno v: Toxics, Vol 9, Iss 100, p 100 (2021)
Toxics; Volume 9; Issue 5; Pages: 100
Toxics

Novel per- and polyfluoroalkyl substances (PFAS) were recently identified in drinking water sources throughout North Carolina. These include the perfluoroether acids (PFEAs) perfluoro-2-methoxyacetic acid (PFMOAA), perfluoro-2-methoxypropanoic acid (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de38f1ab4b868ad71ed877ac35e87ffa
https://www.mdpi.com/2305-6304/9/5/100

Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes

Autor: Hyo-Bum Kwak, Ronald N. Cortright, P. Darrell Neufer, Julie H. Cox, Tracey L. Woodlief, Robert C. Hickner, Thomas D. Green

Publikováno v: International Journal of Environmental Research and Public Health
Volume 16
Issue 7
International Journal of Environmental Research and Public Health, Vol 16, Iss 7, p 1157 (2019)

In rodent skeletal muscle, acyl-coenzyme A (CoA) synthetase 5 (ACSL-5) is suggested to localize to the mitochondria but its precise function in human skeletal muscle is unknown. The purpose of these studies was to define the role of ACSL-5 in mitocho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58548a41f755df7fb1bb0477d0ee19fa

Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial

Autor: Giovanna Distefano, Gabe Dubis, John M. Jakicic, Elvis A. Carnero, Robert A. Standley, Bret H. Goodpaster, Steve J. Anthony, Joseph A. Houmard, Tracey L. Woodlief, Paul M. Coen

Publikováno v: Obesity. 23:2454-2461

Objective Roux-en-Y gastric bypass (RYGB) surgery can cause profound weight loss and improve overall cardiometabolic risk factors. Exercise (EX) training following RYGB can provide additional improvements in insulin sensitivity (SI) and cardiorespira

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad8a773f1531e301f189700a350dc8cc
https://doi.org/10.1002/oby.21332

PD51-06 SALVAGE ROBOT ASSISTED RADICAL PROSTATECTOMY AFTER PRIMARY RADIATION OR ABLATION TREATMENT: WHAT HAVE WE LEARNED? ASSESSING THE LEARNING CURVE IN TERMS OF MORBIDITY, ONCOLOGICAL AND FUNCTIONAL OUTCOMES

Autor: Gabriel Ogaya, Eduardo Hernandez-Cardona, Hariharan Palayapalayam Ganapathi, Vipul Patel, Bernardo Rocco, Travis Rogers, Xavier Bonet, Tracey L. Woodlief, Rafael Coelho

Publikováno v: Journal of Urology. 197

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e08c13048543de4869d19b51e403102
https://doi.org/10.1016/j.juro.2017.02.2206