Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Tracey E. Swingler"'
Autor:
Linh Le, Lingzi Niu, Matthew J. Barter, David A. Young, Tamas Dalmay, Ian M. Clark, Tracey E. Swingler
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract MicroRNAs have been shown to play a role in cartilage development, homeostasis and breakdown during osteoarthritis. We previously identified miR-3085 in humans as a chondrocyte-selective microRNA, however it could not be detected by Northern
Externí odkaz:
https://doaj.org/article/cfc83db974f44c4a99653de7ef60af7c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 554 (2022)
The complete molecular mechanisms underlying the pathophysiology of Alzheimer’s disease (AD) remain to be elucidated. Recently, microRNA-455-3p has been identified as a circulating biomarker of early AD, with increased expression in post-mortem bra
Externí odkaz:
https://doaj.org/article/597aef6501994b129a0f5677fc187913
Autor:
Colin S Brown, Maria Diaz, Luke Bedford, Ana P. Tedim, Steven Rudder, Meera Chand, Muhammad Yasir, Luke Griffith, Will Potter, Rachel Gilroy, Nicholas M. Thomson, Rachael Stanley, Emma Meader, Robert A Kingsley, Ana Victoria Gutierrez, S. J. Louise Smith, Thanh Le-Viet, John Wain, Ian G. Charles, Alexander J. Trotter, Alp Aydin, Ngozi Elumogo, Justin O'Grady, Gemma L. Kay, Reenesh Prakash, Dheeraj K. Sethi, Rose K Davidson, Claire Stuart, Evelien M. Adriaenssens, Alison E Mather, Dinesh Aggarwal, Nabil-Fareed Alikhan, Andrew J. Page, Lizzie Meadows, Anastasia Kolyva, David Baker, Mark A. Webber, Lindsay Coupland, Leonardo de Oliveira Martins, Andrew Bell, Tracey E. Swingler, Samir Dervisevic
Publikováno v:
Microbial genomics
The COVID-19 pandemic has spread rapidly throughout the world. In the UK, the initial peak was in April 2020; in the county of Norfolk (UK) and surrounding areas, which has a stable, low-density population, over 3200 cases were reported between March
Autor:
Will Potter, Luke Bedford, Maria Diaz, Robert A. Kingsley, Lizzie Meadows, Meera Chand, Claire Stuart, Evelien M. Adriaenssens, Ian G. Charles, Nabil-Fareed Alikhan, Alexander J. Trotter, Rachael Stanley, Dheeraj K. Sethi, Nicholas M. Thomson, John Wain, Luke Griffith, Anastasia Kolyva, Dave Baker, Reenesh Prakash, Ana P. Tedim, Thanh Le-Viet, Samir Dervisevic, Alison E. Mather, Gemma L. Kay, Dinesh Aggarwal, Steven Rudder, Rose K Davidson, Rachel Gilroy, Mark A. Webber, Tracey E. Swingler, Andrew J. Page, S. J. Louise Smith, Ngozi Elumogo, Emma Meader, Alp Aydin, Lindsay Coupland, Andrew Bell, Ana Victoria Gutierrez, Leonardo de Oliveira Martins, Colin S Brown, Justin O'Grady
The COVID-19 pandemic has spread rapidly throughout the world. In the UK, the initial peak was in April 2020; in the county of Norfolk (UK) and surrounding areas, which has a stable, low-density population, over 3,200 cases were reported between Marc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b87ecdebd9c2afdf394ba95b042fc4
https://doi.org/10.1101/2020.09.28.20201475
https://doi.org/10.1101/2020.09.28.20201475
Autor:
Ian M. Clark, Lingzi Niu, David Young, Tamas Dalmay, L. Le, Matt J. Barter, Tracey E. Swingler
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
MicroRNAs have been shown to play a role in cartilage development, homeostasis and breakdown during osteoarthritis. We previously identified miR-3085 in humans as a chondrocyte-selective microRNA, however it could not be detected by Northern blot. Th
Autor:
Katarzyna A. Piróg, Robert M. Jackson, Tamas Dalmay, Matt J. Barter, Dimitra Tsompani, Sarah Charlton, Andrew J. Skelton, David Young, Kathleen Cheung, Tracey E. Swingler, Jamie Soul, Ian M. Clark, Louise N. Reynard, N. Crowe, Yao Hao, Steven Woods, Colin G. Miles
Publikováno v:
Woods, S, Charlton, S, Cheung, K, Hao, Y, Soul, J, Reynard, L N, Crowe, N, Swingler, T E, Skelton, A J, Piróg, K A, Miles, C G, Tsompani, D, Jackson, R M, Dalmay, T, Clark, I M, Barter, M J & Young, D A 2020, ' microRNA-seq of cartilage reveals an over-abundance of miR-140-3p which contains functional isomiRs ', RNA (New York, N.Y.) . https://doi.org/10.1261/rna.075176.120
RNA
RNA
MiR-140 is selectively expressed in cartilage. Deletion of the entire miR-140 locus in mice results in growth retardation and early-onset osteoarthritis-like pathology, however the relative contribution of miR-140-5p or miR-140-3p to the phenotype re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640a49e1e7871988538477c18d056f34
https://www.research.manchester.ac.uk/portal/en/publications/micrornaseq-of-cartilage-reveals-an-overabundance-of-mir1403p-which-contains-functional-isomirs(25abf5c9-f846-4858-b0ae-09f5d2f6babb).html
https://www.research.manchester.ac.uk/portal/en/publications/micrornaseq-of-cartilage-reveals-an-overabundance-of-mir1403p-which-contains-functional-isomirs(25abf5c9-f846-4858-b0ae-09f5d2f6babb).html
Autor:
Tracey E, Swingler, Lingzi, Niu, Perry, Smith, Paige, Paddy, Linh, Le, Matthew J, Barter, David A, Young, Ian M, Clark
Publikováno v:
Clinical and experimental rheumatology. 37(5)
MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression and have been shown to have key roles in both chondrocyte development and cartilage homeostasis with age. Deletion of all microRNAs in chondrocytes leads to skeletal
Autor:
Sarah J. B. Snelling, L. Le, Tracey E. Swingler, Rose K Davidson, Ian M. Clark, K.L. Culley, Andrew Carr, Matt J. Barter, Andrew Price
Publikováno v:
Osteoarthritis and Cartilage
Summary Objective Dickkopf-3 (Dkk3) is a non-canonical member of the Dkk family of Wnt antagonists and its upregulation has been reported in microarray analysis of cartilage from mouse models of osteoarthritis (OA). In this study we assessed Dkk3 exp
Publikováno v:
Osteoarthritis and Cartilage. 26:S164-S165
Autor:
Lingzi Niu, Matt J. Barter, David Young, Simon T. Donell, Ian M. Clark, Tamas Dalmay, N. Crowe, L. Le, Tracey E. Swingler
Publikováno v:
Osteoarthritis and Cartilage. 26:S161-S162