Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tracey Avequin"'
Autor:
Tracey Avequin, Kin H. Lau, Althea N. Waldhart, Hannah Guak, Holly Dykstra, Connie Krawczyk, Ning Wu
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107163- (2023)
Summary: Obese individuals experience low grade inflammation initiated within their adipose tissue. However, the early events that lead to the release of these inflammatory factors from adipose tissue are poorly characterized. To separate glucose eff
Externí odkaz:
https://doaj.org/article/0368fc9a315e495197f489861e05bdad
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106538- (2023)
Summary: While TXNIP (thioredoxin interacting protein) in the plasma membrane and vesicular location is known to negatively regulate cellular glucose uptake by facilitating glucose transporter endocytosis, the function of TXNIP in the nucleus is far
Externí odkaz:
https://doaj.org/article/83167db2dc5b46b2bdf2956d7379a0be
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105848- (2023)
Summary: Brown adipose tissue (BAT) has the ability to burn calories as heat. Utilizing BAT thermogenesis is thus an attractive way to combat obesity. However, the transcriptional network resulting in the lipid synthesis to oxidation shift during the
Externí odkaz:
https://doaj.org/article/ef8065ddfd0840fcaadee79c73ede1fe
Autor:
Marine Pons, Magalie Lecourtois, Tracey Avequin, Laetitia Miguel, Dominique Campion, Thierry Frebourg
Publikováno v:
Brain Research
Brain Research, Elsevier, 2018, 1695, pp.1-9. ⟨10.1016/j.brainres.2018.05.021⟩
Brain Research, Elsevier, 2018, 1695, pp.1-9. ⟨10.1016/j.brainres.2018.05.021⟩
TDP-43 is a major disease-causing protein in amyotrophic lateral sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). Today, >50 missense mutations in the TARDBP/TDP-43 gene have been described in patients with FTLD/ALS. However, the functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a27999daa827e850451f6a7a6b80aa
https://hal-normandie-univ.archives-ouvertes.fr/hal-02330526
https://hal-normandie-univ.archives-ouvertes.fr/hal-02330526
Publikováno v:
Cancer Research. 78:3190-3190
Background: High-risk neuroblastoma (HRNB) is an aggressive form of the most common extracranial solid tumor cancer in children, often characterized by amplified levels of MYCN. HRNB patients in remission have a high relapse rate, resulting in poor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef45f0f2325bc6ea03bc5328ae7bb78
https://doi.org/10.1158/1538-7445.am2018-3190
https://doi.org/10.1158/1538-7445.am2018-3190
Autor:
Laetitia Miguel, Dominique Campion, Marine Pons, François Juge, Thierry Frebourg, Magalie Lecourtois, Tracey Avequin, Camille Miel
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2017, 26 (17), pp.3396-3408. ⟨10.1093/hmg/ddx229⟩
Human Molecular Genetics, Oxford University Press (OUP), 2017, 26 (17), pp.3396-3408. ⟨10.1093/hmg/ddx229⟩
TDP-43 is a critical RNA-binding factor associated with RNA metabolism. In the physiological state, maintaining normal TDP-43 protein levels is critical for proper physiological functions of the cells. As such, TDP-43 expression is tightly regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d19cfa31bb7409af49bd78f9827ada0
https://hal-normandie-univ.archives-ouvertes.fr/hal-02330529
https://hal-normandie-univ.archives-ouvertes.fr/hal-02330529
Autor:
Abhinav Nagulapally, Tracey Avequin, Jeffrey P. Bond, Giselle Saulnier Sholler, Sarah DeCou, Ping Zhao
Publikováno v:
Cancer Research. 77:691-691
Background: Neuroblastoma (NB) is the most common extracranial solid pediatric tumor and is associated with MYCN amplification. MYCN is a regulator of ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine biosynthesis. Inhibition of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56539bbedbe16d9a88fd9b9a026d98b
https://doi.org/10.1158/1538-7445.am2017-691
https://doi.org/10.1158/1538-7445.am2017-691
Autor:
Jeffrey P. Bond, Tracey Avequin, Ping Zhao, Giselle Saulnier Sholler, Abhinav Nagulapally, Max S. Wicha, Ebrahim Azizi
Publikováno v:
Cancer Research. 76:2474-2474
Background: Difluoromethylornithine (DFMO) has shown promise in recent clinical trials as a therapeutic agent in treating neuroblastoma (NB). High-risk NB patients have an approximately 50% relapse rate, after which survival rate drops to lower than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b52fe9e1357f33f424885aa0492e658
https://doi.org/10.1158/1538-7445.am2016-2474
https://doi.org/10.1158/1538-7445.am2016-2474
Autor:
Lewis, Elizabeth C., Kraveka, Jacqueline M., Ferguson, William, Eslin, Don, Brown, Valerie I., Bergendahl, Genevieve, Roberts, William, Wada, Randal K., Oesterheld, Javier, Mitchell, Deanna, Foley, Jessica, Zage, Peter, Rawwas, Jawhar, Rich, Maria, Lorenzi, Elizabeth, Broglio, Kristine, Berry, Donald, Saulnier Sholler, Giselle L.
Publikováno v:
International Journal of Cancer; Dec2020, Vol. 147 Issue 11, p3152-3159, 8p
Publikováno v:
Obesity, Fitness & Wellness Week; 7/3/2023, p1245-1245, 1p