Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Tracey Ann Sambrook"'
Autor:
Christopher William Murray, Joseph E. Coyle, Sharna J. Rich, Anne Cleasby, Tracey Ann Sambrook, S. Saalau-Bethell, Jeff Yon, Valerio Berdini, Mladen Vinkovic, Victoria Lock, M. Alistair O’Brien, Miles Congreve, Harren Jhoti
Publikováno v:
'ChemMedChem ', vol: 9, pages: 823-832 (2014)
Chemmedchem
Chemmedchem
Soluble adenylate cyclases catalyse the synthesis of the second messenger cAMP through the cyclisation of ATP and are the only known enzymes to be directly activated by bicarbonate. Here, we report the first crystal structure of the human enzyme that