Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Tracey A. Ignatowski"'
Autor:
Peter Bloomingdale, Cristina Meregalli, Kevin Pollard, Annalisa Canta, Alessia Chiorazzi, Giulia Fumagalli, Laura Monza, Eleonora Pozzi, Paola Alberti, Elisa Ballarini, Norberto Oggioni, Louise Carlson, Wensheng Liu, Mehrnoosh Ghandili, Tracey A. Ignatowski, Kelvin P. Lee, Michael J. Moore, Guido Cavaletti, Donald E. Mager
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Chemotherapy-induced peripheral neurotoxicity is a common dose-limiting side effect of several cancer chemotherapeutic agents, and no effective therapies exist. Here we constructed a systems pharmacology model of intracellular signaling in peripheral
Externí odkaz:
https://doaj.org/article/1ccf464a944a4141a28474e8a0809c1d
Autor:
Courtney A. Benson, Hana R. Powell, Michal Liput, Siddhartha Dinham, David A. Freedman, Tracey A. Ignatowski, Ewa K. Stachowiak, Michal K. Stachowiak
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Schizophrenia (SZ) is a neurodevelopmental genetic disorder in which maternal immune activation (MIA) and increased tumor necrosis factor-α (TNF-α) may contribute. Previous studies using iPSC-derived cerebral organoids and neuronal cells demonstrat
Externí odkaz:
https://doaj.org/article/45bfad2173fe44148cbaebd3973665a1
Publikováno v:
Current medical research and opinion. 38(12)
This study aimed to describe the neurological improvements in a patient with severe long COVID brain dysfunction following perispinal etanercept administration. Perispinal administration of etanercept, a novel method designed to enhance its brain del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b35a5f7feb3a1c8b31ce6a218d6b47
https://pubmed.ncbi.nlm.nih.gov/35791687
https://pubmed.ncbi.nlm.nih.gov/35791687
Autor:
Asif H. Abidi, Tracey A. Ignatowski, Zach LaMacchia, Robert N. Spengler, Tariq Ahmed, Edward L Tobinick, Muhammad Jaffari, Natasha Singh
Publikováno v:
Brain, Behavior, and Immunity. 82:93-105
Neuropathic pain is chronic pain that follows nerve injury, mediated in the brain by elevated levels of the inflammatory protein tumor necrosis factor-alpha (TNF). We have shown that peripheral nerve injury increases TNF in the hippocampus/pain perce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab1415e07bfe160e873837dcad55615
https://doi.org/10.1016/j.bbi.2019.07.036
https://doi.org/10.1016/j.bbi.2019.07.036
Autor:
Paras N. Prasad, Vijaya Prakash Krishnan Muthaiah, Tracey A. Ignatowski, Rebecca Schmitt, Kathiravan Kaliyappan, Supriya D. Mahajan
Publikováno v:
Brain research. 1770
Disruption of the blood-brain barrier (BBB) is a critical component of traumatic brain injury (TBI) progression. However, further research into the mechanism of BBB disruption and its specific role in TBI pathophysiology is necessary. To help make pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c28785d033a9f3f021323d2fcfd512
https://pubmed.ncbi.nlm.nih.gov/34474000
https://pubmed.ncbi.nlm.nih.gov/34474000
Publikováno v:
World Journal of Anesthesiology. 7:10-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4721312394679f1ac12cf10a23bbb791
https://doi.org/10.5313/wja.v7.i2.10
https://doi.org/10.5313/wja.v7.i2.10
Publikováno v:
Brain, behavior, and immunity. 77
Physical exercise is one of the most important factors improving quality of life, but it is not feasible for patients with morbidity or limited mobility. Most previous studies focused on high-intensity or long-term exercise that causes metabolic stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5c80f1fcbb48beab85e8afd6595ddc
https://pubmed.ncbi.nlm.nih.gov/30394312
https://pubmed.ncbi.nlm.nih.gov/30394312
Autor:
Tracey A. Ignatowski, Justin N. Siemian, Jingwei Tian, Vilma Spreuer, Zach LaMacchia, Pablo M. Paez, Jun-Xu Li, Yanan Zhang
Chronic pain is a large, unmet public health problem. Recent studies have demonstrated the importance of neuroinflammation in the establishment and maintenance of chronic pain. However, pharmacotherapies that reduce neuroinflammation have not been su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5c28c29ce37c97de6feaec7bbe316b
https://europepmc.org/articles/PMC5959749/
https://europepmc.org/articles/PMC5959749/
Publikováno v:
Journal of Neurology and Neurobiology. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee560240a59432cfe5cfdbbe934fa862
https://doi.org/10.16966/2379-7150.e111
https://doi.org/10.16966/2379-7150.e111
Publikováno v:
Neuroscience & Biobehavioral Reviews. 53:139-159
Major depression and chronic pain are significant health problems that seriously impact the quality of life of affected individuals. These diseases that individually are difficult to treat often co-exist, thereby compounding the patient's disability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b663d5621898fa82c8a6991e4fd4d3
https://doi.org/10.1016/j.neubiorev.2015.03.014
https://doi.org/10.1016/j.neubiorev.2015.03.014