Corneal Endothelial Cell Toxicity Determines Long-Term Outcome After Ocular Exposure to Sulfur Mustard Vapor

Autor: Dominique L. Nguyen, Megan E Lyman, Marian R. Nelson, Tracey A. Hamilton, Sarah E Wolfe, Margaret M Eisen, Mark Mangkhalakhili, Kathleen T Pagarigan, Celinia A. Ondeck, Denise M. Kniffin, Patrick M. McNutt

Publikováno v: Cornea. 39:640-648

Purpose Ocular exposure to sulfur mustard (SM) vapor causes acute loss of corneal endothelial cells (CECs). Persistent corneal endothelial pathologies are observed in eyes that do not recover from SM exposure, suggesting that endothelial toxicity con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5ad9d5e3658886a5424587d49ba9b0
https://doi.org/10.1097/ico.0000000000002278

List of contributors

Autor: Arturo Anadón, Rudolf Andrys, Pavel Avdonin, Jiri Bajgar, Mahdi Balali-Mood, Frank Balszuweit, Atrayee Banerjee, Cheryl B. Bast, Daria Belinskaia, Vijay K. Bharti, Claire E. Bollinger, Robert P. Casillas, Ryan Clark, Edward D. Clarkson, Toby B. Cole, Rhian B. Cope, Robert W. Coppock, Lucio G. Costa, Wolf-D. Dettbarn, Alzbeta Dlabkova, Robin B. Doss, Margitta M. Dziwenka, Jorge Estevez, Tim J. Evans, John K. Fink, Swaran J.S. Flora, Clement E. Furlong, Josef Fusek, Jacqueline Garrick, Jeffery M. Gearhart, Donald R. Gerecke, Dana F. Glass-Mattie, Saryu Goel, Nikolay Goncharov, Richard K. Gordon, Joshua P. Gray, Zoran Grubic, Kavita Gulati, Ramesh C. Gupta, Sharon M. Gwaltney-Brant, Tracey A. Hamilton, Kenneth J. Harris, Darryl B. Hood, Edward M. Jakubowski, Richard Jenkins, David A. Jett, Yuqin Jiao, Harald John, Nathan H. Johnson, Milan Jokanović, Daniel Jun, Georgy Karakashev, Jiri Kassa, Maja Katalinic, Kai Kehe, Natalia Khlebnikova, Urmila P. Kodavanti, Ekaterina Korf, Nadezhda Koryagina, Bojan Kovač, Gopala Krishna, Mayur Krishna, Kamil Kuca, Dinesh Kumar, Yukio Kuroiwa, Sergey Kuznetsov, Kamil Kuča, Joseph C. Larsen, Mikhail Leninskiy, Jing Liu, Heather Lochotzki, Oksana Lockridge, Jordana Lockwich, Bommanna G. Loganathan, Dragana Lončar-Stojiljković, Sofya V. Lushchekina, Megan E. Lyman, Mark Maguire, Galina F. Makhaeva, Jitendra K. Malik, David Malinak, Tomaz Mars, Judit Marsillach, María-Rosa Martínez-Larrañaga, Patrick Masson, Shigeki Masunaga, Monique McCallister, Linda A. McCauley, Roger O. McClellan, Patrick M. McNutt, Edward C. Meek, Elaine Merrill, Sylvia Milanez, Igor Mindukshev, Katarina Mis, Jan Misik, Michael J. Murphy, Kamil Musilek, Tamie Nakajima, Marian R. Nelson, Eugenie Nepovimova, Tetsu Okumura, Jiri Patocka, Katarina Pegan, Jaroslav Pejchal, Sergej Pirkmajer, René Pita, Jason Pitt, Yiuka Pitt, Gennady E. Platoff, Carey N. Pope, Andrey Radilov, Anu Rahal, Aramandla Ramesh, Arunabha Ray, Vladimir Rembovskiy, Raina Rhoades, Rudy J. Richardson, Dragana Ristić, Peter J. Robinson, Alejandro Romero, Chris Ruark, Harry Salem, Natalia Samchenko, Tetsuo Satoh, Russell E. Savage, Elena Savelieva, Lawrence M. Schopfer, Alfred M. Sciuto, Yasuo Seto, Michael P. Shakarjian, Vladimir Shmurak, Adam Skarka, Ranko Škrbić, Miguel Sogorb, Shardell M. Spriggs, Sakshi Srivastava, Dirk Steinritz, Miloš P. Stojiljković, Neera Tewari-Singh, Horst Thiermann, Suresh Kumar Thokchom, Larry J. Thompson, Anton Ukolov, Luis G. Valerio, M.J. van der Schans, Daya R. Varma, Eugenio Vilanova, Annetta Watson, Sanjeeva J. Wijeyesakere, Tina Wismer, R. Mark Worden, Franz Worek, Linzzi K. Wright, Hidenori Yamasue, Takemi Yoshida, Toshiharu Yoshioka, Robert A. Young, Snjezana Zaja-Milatovic, Valeriy Zinchenko, Csaba K. Zoltani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d85fe69eddc7f1d019dfca73327140c3
https://doi.org/10.1016/b978-0-12-819090-6.00078-7

The physiology and toxicology of acute inhalation phosphine poisoning in conscious male rats

Autor: Heidi Hoard-Fruchey, Justin Tressler, Alfred M. Sciuto, Jaclynn Andres, Tracey A. Hamilton, Cristin Rothwell, Katherine Sherman, Rebecca J Lewandowski, Benjamin Wong, Jennifer Devorak

Publikováno v: Inhalation Toxicology. 29:494-505

Phosphine (PH3) is a toxidrome-spanning chemical that is widely used as an insecticide and rodenticide. Exposure to PH3 causes a host of target organ and systemic effects, including oxidative stress, cardiopulmonary toxicity, seizure-like activity an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff84a93e75d4f16c2113baba8a2f73f
https://doi.org/10.1080/08958378.2017.1406564

Identification and characterization of novel catalytic bioscavengers of organophosphorus nerve agents

Autor: Sean M. Hodgins, Tamara C. Otto, Greg A Saturday, Monika A Kauffman, Tracey A. Hamilton, Jennifer R Scott, Robert C. diTargiani, Erin P Sarricks, James H Hughes, Douglas M. Cerasoli

Publikováno v: Chemico-Biological Interactions. 203:186-190

In an effort to discover novel catalytic bioscavengers of organophosphorus (OP) nerve agents, cell lysates from a diverse set of bacterial strains were screened for their capacity to hydrolyze the OP nerve agents VX, VR, and soman (GD). The library o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d78bbf7eb7b94de0fba1406c97ac05f
https://doi.org/10.1016/j.cbi.2012.09.009

Pathogenesis of Acute and Delayed Corneal Lesions After Ocular Exposure to Sulfur Mustard Vapor

Autor: Denise Milhorn, Patrick M. McNutt, Tracey A. Hamilton, Adam M. Swartz, Marian R. Nelson, Richard Lawrence, Angela Adkins

Publikováno v: Cornea. 31:280-290

PURPOSE: Sulfur mustard (SM) exposure results in dose-dependent morbidities caused by cytotoxicity and vesication. Although lesions resulting from ocular exposure often resolve clinically, an idiopathic delayed mustard gas keratopathy (MGK) can devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297c88fdd10204d2a3411f97dcb9535c
https://doi.org/10.1097/ico.0b013e31823d02cd