Výsledky vyhledávání - "Tracess B. Smalley"

Akademický článek

Structural perspectives on recent breakthrough efforts toward direct drugging of RAS and acquired resistance

Autor: Jameela Lokhandwala, Tracess B. Smalley, Timothy H. Tran

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

The Kirsten rat sarcoma viral oncoprotein homolog (KRAS) is currently a primary focus of oncologists and translational scientists, driven by exciting results with KRAS-targeted therapies for non-small cell lung cancer (NSCLC) patients. While KRAS mut

Externí odkaz: https://doaj.org/article/aca5e330a22840b09ee81bb5d601f5c2

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Tuaimenals B–H, Merosesquiterpenes from the Irish Deep-Sea Soft Coral Duva florida with Bioactivity against Cervical Cancer Cell Lines

Autor: Joshua T. Welsch, Tracess B. Smalley, Jenet K. Matlack, Nicole E. Avalon, Jennifer M. Binning, Mark P. Johnson, A. Louise Allcock, Bill J. Baker

Publikováno v: Journal of Natural Products. 86:182-190

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72ac2a7957e5a62d3b44eccc1a97b92d
https://doi.org/10.1021/acs.jnatprod.2c00898

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Abstract 3844: A biophysical investigation into the binding interactions of novel anti-cancer inhibitors of atypical protein kinase C (aPKCs)

Autor: Radwan Ebna Noor, Tracess B. Smalley, Mildred Acevedo-Duncan

Publikováno v: Cancer Research. 83:3844-3844

The aim of this study is to address the challenge of the expression of recombinant atypical protein kinase C (aPKCs) in a bacterial system and understand the binding interactions of novel anti-cancer inhibitors of aPKCs. The Protein kinase Cs (PKCs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c68c8466c6bf1c0d860ea7c94110ff2c
https://doi.org/10.1158/1538-7445.am2023-3844

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