Zobrazeno 1 - 10
of 631
pro vyhledávání: '"Trace amine-associated receptor"'
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
For over seven decades, dopamine receptor 2 (D2 receptor) antagonists remained the mainstay treatment for neuropsychiatric disorders. Although it is effective for treating hyperdopaminergic symptoms, it is often ineffective for treating negative and
Externí odkaz:
https://doaj.org/article/48b7396d40bf4f438918c8fc0fa0897f
Autor:
Nina Dedic, Lien Wang, Eva Hajos-Korcsok, Jacob Hecksher-Sørensen, Urmas Roostalu, Steven P. Vickers, Serena Wu, Christoph Anacker, Colleen Synan, Philip G. Jones, Snezana Milanovic, Seth C. Hopkins, Linda J. Bristow, Kenneth S. Koblan
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101883- (2024)
Objective: Metabolic Syndrome, which can be induced or exacerbated by current antipsychotic drugs (APDs), is highly prevalent in schizophrenia patients. Recent preclinical and clinical evidence suggest that agonists at trace amine-associated receptor
Externí odkaz:
https://doaj.org/article/b7fe5a8971f046fa9b051d0ee080c127
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Trace amines, such as tyramine, are endogenous amino acid metabolites that have been hypothesized to promote headache. However, the underlying cellular and molecular mechanisms remain unknown. Methods Using patch-clamp recording,
Externí odkaz:
https://doaj.org/article/bb694e633b6f4174a3eafd48822332d2
Autor:
Sergey A. Apryatin, Ilya S. Zhukov, Ekaterina A. Zolotoverkhaya, Saveliy R. Kuvarzin, Temirkan A. Khunagov, Sanelya V. Ushmugina, Victor M. Klimenko
Publikováno v:
Neurology International, Vol 15, Iss 1, Pp 339-351 (2023)
Trace amines and their receptors are a family of G protein-coupled receptors widely distributed in the central nervous system and periphery. The trace amine-associated receptor 1 (TAAR1) plays a significant role as a therapeutic target for schizophre
Externí odkaz:
https://doaj.org/article/d02ba62553044dd58b3721cf27fb1594
Autor:
Ko Ito, Masamichi Shinoda, Kumi Soma, Daisuke Ikutame, Eiji Ikami, Yosuke Mizuno, Michihiko Usui, Seiji Asoda, Tsuyoshi Sato
Publikováno v:
Stresses, Vol 3, Iss 1, Pp 58-68 (2022)
(1) Background: Chronic psychosocial stress can lead to oral dysesthesia with tongue pain. We examined whether psychosocial stress causes orofacial pain, and analyzed the comprehensive gene expression patterns of circulating cells and transient recep
Externí odkaz:
https://doaj.org/article/f5917bb2887f4d0795ffbb54b1d2dc41
Akademický článek
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Akademický článek
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Autor:
Yunjie Wang, Zhaofeng Liu, Jing Lu, Wenyan Wang, Lin Wang, Yifei Yang, Hongbo Wang, Liang Ye, Jianzhao Zhang, Jingwei Tian
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Schizophrenia is a serious mental illness that requires effective treatment with minimal adverse effects. As preclinical and clinical research progresses, trace amine-associated receptor 1 (TAAR1) is becoming a potential new target for
Externí odkaz:
https://doaj.org/article/1bc5711727fb4d51b50926082b674694
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1977 (2023)
All antipsychotics currently used in clinic block D2 dopamine receptors. Trace amine-associated receptor 1 is emerging as a new therapeutic target for schizophrenia and several other neuropsychiatric disorders. SEP-363856 (International Nonproprietar
Externí odkaz:
https://doaj.org/article/ff4edba3210347a99e361d5d51064936
Akademický článek
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