Výsledky vyhledávání - "Trabold, Katharina"

Additional file 7: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S7. Syk and PLCγ2 tyrosine phosphorylation is also increased and prolonged at 10 μM riociguat. Washed human platelets (WP) were pre-incubated for 5 min at 37 °C with vehicle control (DMSO) and 10 μM riociguat, respectively prior to stimula

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Additional file 1: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S1. Echicetin purification and qualitative validation. Echicetin was isolated from the snake venom of Echis carinatus sochureki by affinity chromatography followed by anion exchange chromatography using DEAE column. a Elution was performed wit

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Additional file 6: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S6. Syk and PLCγ2 tyrosine phosphorylation is also increased and prolonged at 1 nM iloprost. Washed human platelets (WP) were pre-incubated 3 min at 37 °C in the presence or absence of iloprost (1 nM) prior to stimulation with EB. Phosphoryl

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Additional file 5: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S5. Iloprost and riociguat inhibit EB-induced platelet aggregation in a dose-dependent manner and induce stable VASP S157 and S239 phosphorylation. Representative curves of the effect of increased concentrations of a iloprost and b riociguat o

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Additional file 8: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S8. Iloprost and riociguat inhibit convulxin-induced platelet aggregation but not Syk activation. Washed human platelets (WP) were pre-incubated with iloprost (2 nM, 3 min) or riociguat (20 μM, 2 min) prior to stimulation with 50 ng/ml convul

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Additional file 3: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S3. EB-induced platelet aggregation is dependent on src family kinases (SFKs). Washed human platelets (WP) were pre-incubated for 5 min with the SFK inhibitor, PP2 (10 μM) or with its inactive analogue, PP3 (10 μM) prior to stimulation with

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Additional file 4: of cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

Autor: Makhoul, Stephanie, Trabold, Katharina, Gambaryan, Stepan, Tenzer, Stefan, Pillitteri, Daniele, Walter, Ulrich, Jurk, Kerstin

Figure S4. Syk inhibitors diminish EB-induced general tyrosine phosphorylation and vWF/ristocetin-induced platelet aggregation and phosphorylation of Syk 525/526, LAT Y191 and Akt S473. a Washed human platelets (WP) were pre-incubated with 2 differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62ed33cbe413284cb82491dc4f43df9

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