Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tr, Castañeda"'
Autor:
Tschöp M, Tr, Castañeda, Hg, Joost, Thöne-Reineke C, Ortmann S, Klaus S, Mm, Hagan, Pc, Chandler, Kd, Oswald, Sc, Benoit, Rj, Seeley, Kp, Kinzig, Th, Moran, Ag, Beck-Sickinger, Koglin N, Rj, Rodgers, Je, Blundell, Ishii Y, Ah, Beattie, Holch P, Db, Allison, Raun K, Madsen K, Bs, Wulff, Ce, Stidsen, Marc Birringer, Oj, Kreuzer, Schindler M, Arndt K, Rudolf K, Mark M, Xy, Deng, Dc, Whitcomb, Halem H, Taylor J, Dong J, Datta R, Culler M, Craney S, Flora D, Smiley D, Ml, Heiman, Dc, Withcomb
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6561f97f6e6edf1962855b390cdb6995
http://europepmc.org/abstract/med/15243972
http://europepmc.org/abstract/med/15243972
Autor:
Vacca M; TVP Lab, WT/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK. michele.vacca@uniba.it.; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy. michele.vacca@uniba.it.; Laboratory of Liver Metabolism and MASLD, Roger Williams Institute of Hepatology, London, UK. michele.vacca@uniba.it., Kamzolas I; TVP Lab, WT/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK., Harder LM; Research and Early Development, Novo Nordisk A/S, Måløv, Copenhagen, Denmark., Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Trautwein C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Hatting M; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Ross T; Internal Medicine research Research Unit, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Bernardo B; Internal Medicine research Research Unit, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Oldenburger A; CardioMetabolic Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Hjuler ST; Research and Early Development, Novo Nordisk A/S, Måløv, Copenhagen, Denmark., Ksiazek I; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland., Lindén D; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca BioPharmaceuticals R&D, Gothenburg, Sweden.; Division of Endocrinology, Department of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Schuppan D; Institute of Translational Immunology and Research Center for Immunotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany., Rodriguez-Cuenca S; TVP Lab, WT/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Tonini MM; Luxembourg Institute of Health, Translational Medicine Operations Hub, Dudelange, Luxembourg., Castañeda TR; R&D Diabetes & Portfolio Innovation and Excellence, Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt, Germany., Kannt A; R&D Diabetes, Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Fraunhofer Innovation Center TheraNova and Goethe University, Frankfurt, Germany., Rodrigues CMP; Research Institute for Medicines, Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Cockell S; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Govaere O; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Daly AK; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Allison M; Liver Unit, Cambridge University Hospitals NHS Foundation Trust & Cambridge NIHR Biomedical Research Centre, Cambridge, UK., Honnens de Lichtenberg K; Research and Early Development, Novo Nordisk A/S, Måløv, Copenhagen, Denmark., Kim YO; Institute of Translational Immunology and Research Center for Immunotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany., Lindblom A; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca BioPharmaceuticals R&D, Gothenburg, Sweden., Oldham S; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca BioPharmaceuticals R&D, Gaithersburg, MD, USA., Andréasson AC; Bioscience Cardiovascular, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca BioPharmaceuticals R&D, Gothenburg, Sweden., Schlerman F; Inflammation and Immunology Research Unit, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Marioneaux J; Fleur De Lis Holdings 10201 Dakins Dr. Richmond, Richmond, VA, USA., Sanyal A; Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA., Afonso MB; Research Institute for Medicines, Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Younes R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany., Amano Y; Research, Takeda Pharmaceutical Company Limited, Fujisawa, Japan., Friedman SL; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wang S; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bhattacharya D; Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Simon E; Global Computational Biology and Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Paradis V; Department of Imaging and Pathology, Université Paris Diderot and Hôpital Beaujon, Paris, France., Burt A; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK., Grypari IM; Department of Pathology, Aretaeion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Davies S; Department of Cellular Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Driessen A; Department of Pathology, Antwerp University Hospital, Edegem, Belgium.; Department of Molecular Imaging, Pathology, Radiotherapy, Oncology. Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium., Yashiro H; Research, Takeda Pharmaceuticals Company Limited, Cambridge, MA, USA., Pors S; Gubra, Hoersholm, Denmark., Worm Andersen M; Gubra, Hoersholm, Denmark., Feigh M; Gubra, Hoersholm, Denmark., Yunis C; Pfizer, Inc.; Internal Medicine and Hospital, Pfizer Research and Development, Lake Mary, FL, USA., Bedossa P; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; LiverPat, Paris, France., Stewart M; Mary Lyon Centre, MRC Harwell, Harwell Campus, Oxford, UK., Cater HL; Mary Lyon Centre, MRC Harwell, Harwell Campus, Oxford, UK., Wells S; Mary Lyon Centre, MRC Harwell, Harwell Campus, Oxford, UK., Schattenberg JM; Department of Internal Medicine II, Saarland University Medical Centre, Homburg, Germany., Anstee QM; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK., Tiniakos D; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. Dina.Tiniakos@newcastle.ac.uk.; Department of Pathology, Aretaeion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. Dina.Tiniakos@newcastle.ac.uk., Perfield JW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA. Perfield_james_w@lilly.com., Petsalaki E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK. petsalaki@ebi.ac.uk., Davidsen P; Research and Early Development, Novo Nordisk A/S, Måløv, Copenhagen, Denmark. pkdavidsen@gmail.com.; Ferring Pharmaceuticals A/S, International PharmaScience Center, Copenhagen, Denmark. pkdavidsen@gmail.com., Vidal-Puig A; TVP Lab, WT/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK. ajv22@medschl.cam.ac.uk.; Centro de Investigacion Principe Felipe, Valencia, Spain. ajv22@medschl.cam.ac.uk.
Publikováno v:
Nature metabolism [Nat Metab] 2024 Jun; Vol. 6 (6), pp. 1178-1196. Date of Electronic Publication: 2024 Jun 12.
Autor:
Erdogan BR; Department of Pharmacology, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Türkiye., Michel MB; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany., Matthes J; Centre of Pharmacology, University Medical Center, University of Cologne, Cologne, Germany., Castañeda TR; Sanofi Research and Development, Frankfurt, Germany., Christen U; Pharmazentrum, Goethe University, Frankfurt, Germany., Arioglu-Inan E; Department of Pharmacology, Faculty of Pharmacy, Ankara University, Ankara, Türkiye., Michel MC; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany., Pautz A; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany.
Publikováno v:
Frontiers in pharmacology [Front Pharmacol] 2023 Feb 20; Vol. 14, pp. 1118730. Date of Electronic Publication: 2023 Feb 20 (Print Publication: 2023).
Autor:
Yesilyurt ZE; Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey., Matthes J; Department of Pharmacology, University of Cologne, Cologne, Germany., Hintermann E; Pharmazentrum, Goethe University, Frankfurt, Germany., Castañeda TR; Sanofi Research and Development, Frankfurt, Germany., Elvert R; Sanofi Research and Development, Frankfurt, Germany., Beltran-Ornelas JH; Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico., Silva-Velasco DL; Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico., Xia N; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany., Kannt A; Sanofi Research and Development, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany., Christen U; Pharmazentrum, Goethe University, Frankfurt, Germany., Centurión D; Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico., Li H; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany., Pautz A; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany., Arioglu-Inan E; Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey., Michel MC; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany.
Publikováno v:
Frontiers in physiology [Front Physiol] 2022 Aug 08; Vol. 13, pp. 923555. Date of Electronic Publication: 2022 Aug 08 (Print Publication: 2022).
Autor:
Castañeda TR; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Méndez M; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Davison I; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Elvert R; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Schwahn U; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Boldina G; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Rocher C; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Scherer P; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Singh K; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Bangari DS; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Falkenhahn M; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Kannt A; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Konkar A; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Larsen PJ; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Arbeeny C; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Dhal PK; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.)., Hübschle T; R&D Diabetes (T.R.C., R.E., A.Ka., A.Ko., P.J.L., C.A., T.H.), Integrated Drug Discovery (M.M.), Biomarkers and Clinical Bioanalysis (U.S.), Translational In Vivo Models, Global Discovery Pathology (P.S.), and Global Research Project Management (M.F.), Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt, Germany; C&BD Haverhill Operations, Sanofi GB Genzyme Limited, Haverhill, Suffolk, United Kingdom (I.D.); R&D Translational Sciences France, Bioinformatics, Sanofi, Chilly-Mazarin Cedex, France (C.R.); Translational In Vivo Models, Global Discovery Pathology, Framingham, Massachusetts (K.S., D.S.B.); and Pharmaceutical Development Platform, Sanofi Global R&D, Waltham, Massachusetts (P.K.D.) Thomas.Huebschle@sanofi.com.
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 Feb; Vol. 376 (2), pp. 190-203. Date of Electronic Publication: 2020 Nov 17.
Autor:
Mishra A; Industriepark Höchst 65926 Frankfurt Germany., Castañeda TR; R&D Diabetes Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany., Bader E; Industriepark Höchst 65926 Frankfurt Germany., Elshorst B; Industriepark Höchst 65926 Frankfurt Germany., Cummings S; Global Discovery Pathology Translational In Vivo Models Sanofi Genzyme The Mountain Road Framingham MA 01701 USA., Scherer P; Global Bioimaging Translational In Vivo Models Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany., Bangari DS; Global Discovery Pathology Translational In Vivo Models Sanofi Genzyme The Mountain Road Framingham MA 01701 USA., Loewe C; Industriepark Höchst 65926 Frankfurt Germany., Schreuder H; Industriepark Höchst 65926 Frankfurt Germany., Pöverlein C; Industriepark Höchst 65926 Frankfurt Germany., Helms M; Global Bioimaging Translational In Vivo Models Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany., Jones S; Industriepark Höchst 65926 Frankfurt Germany., Zech G; Industriepark Höchst 65926 Frankfurt Germany., Licher T; Industriepark Höchst 65926 Frankfurt Germany., Wagner M; Industriepark Höchst 65926 Frankfurt Germany., Schudok M; R&D Drug Metabolism and Pharmacokinetics Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany., de Hoop M; Industriepark Höchst 65926 Frankfurt Germany., Plowright AT; Industriepark Höchst 65926 Frankfurt Germany.; Wren Therapeutics Ltd. Department of Chemistry University of Cambridge Lensfield Rd Cambridge CB2 1EW UK., Atzrodt J; R&D Transversal Operations German R&D Hub Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany., Kannt A; R&D Diabetes Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany.; Experimental Pharmacology Medical Faculty Mannheim University of Heidelberg 68167 Mannheim Germany.; Fraunhofer IME Translational Medicine and Pharmacology 60596 Frankfurt Germany., Laitinen I; Global Bioimaging Translational In Vivo Models Sanofi-Aventis Deutschland GmbH Industriepark Höchst 65926 Frankfurt Germany.; Present address: Antaros Medical, Bioventure Hub Mölndal 431 83 Sweden., Derdau V; Industriepark Höchst 65926 Frankfurt Germany.
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2020 Nov 09; Vol. 7 (24), pp. 2002997. Date of Electronic Publication: 2020 Nov 09 (Print Publication: 2020).
Autor:
Schmoll D; Sanofi R&D Frankfurt Germany., Ziegler N; Sanofi R&D Frankfurt Germany., Viollet B; Université de Paris Institut Cochin CNRS UMR 8104 INSERM U1016 Paris France., Foretz M; Université de Paris Institut Cochin CNRS UMR 8104 INSERM U1016 Paris France., Even PC; UMR Nutrition Physiology and Ingestive Behavior AgroParisTech INRA Université Paris-Saclay Paris France., Azzout-Marniche D; UMR Nutrition Physiology and Ingestive Behavior AgroParisTech INRA Université Paris-Saclay Paris France., Nygaard Madsen A; Gubra Hørsholm Denmark., Illemann M; Gubra Hørsholm Denmark., Mandrup K; Gubra Hørsholm Denmark., Feigh M; Gubra Hørsholm Denmark., Czech J; Sanofi R&D Frankfurt Germany., Glombik H; Sanofi R&D Frankfurt Germany., Olsen JA; Sanofi R&D Frankfurt Germany., Hennerici W; Sanofi R&D Frankfurt Germany., Steinmeyer K; Sanofi R&D Frankfurt Germany., Elvert R; Sanofi R&D Frankfurt Germany., Castañeda TR; Sanofi R&D Frankfurt Germany., Kannt A; Sanofi R&D Frankfurt Germany.; Institute of Experimental Pharmacology Medical Faculty Mannheim University of Heidelberg Mannheim Germany.; Fraunhofer IME Translational Medicine and Pharmacology Frankfurt Germany.
Publikováno v:
Hepatology communications [Hepatol Commun] 2020 May 15; Vol. 4 (7), pp. 1056-1072. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).
Autor:
Romacho T; Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; komIT Center of Competence for Innovative Diabetes Therapy, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Sell H; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Indrakusuma I; Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Roehrborn D; Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Castañeda TR; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Jelenik T; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Markgraf D; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Hartwig S; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Weiss J; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Al-Hasani H; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Roden M; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Eckel J; Paul-Langerhans-Group for Integrative Physiology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; komIT Center of Competence for Innovative Diabetes Therapy, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Publikováno v:
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 May 01; Vol. 318 (5), pp. E590-E599. Date of Electronic Publication: 2019 Dec 31.
Autor:
Grandoch M; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Flögel U; Experimental Cardiovascular Imaging, Molecular Cardiology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Virtue S; MRC Metabolic Diseases Unit, Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom., Maier JK; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Jelenik T; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany., Kohlmorgen C; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Feldmann K; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Ostendorf Y; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Castañeda TR; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, Medical Faculty, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Zhou Z; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, Medical Faculty, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Yamaguchi Y; Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Nascimento EBM; Department of Nutrition and Movement Sciences, Maastricht Medical Centre, NUTRIM School of Nutrition and Translational Research in Metabolism, The Netherlands., Sunkari VG; Division of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Goy C; Institute for Clinical Chemistry, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Kinzig M; Institute for Biomedical and Pharmaceutical Research, Nürnberg-Heroldsberg, Germany., Sörgel F; Institute for Biomedical and Pharmaceutical Research, Nürnberg-Heroldsberg, Germany., Bollyky PL; Division of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Schrauwen P; Department of Nutrition and Movement Sciences, Maastricht Medical Centre, NUTRIM School of Nutrition and Translational Research in Metabolism, The Netherlands., Al-Hasani H; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, Medical Faculty, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Keipert S; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München.; Department of Molecular Biosciences, The Wenner-Gren Institute, The Arrhenius Laboratories F3, Stockholm University, SE-106 91 Stockholm, Sweden., Vidal-Puig A; MRC Metabolic Diseases Unit, Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.; WT-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Jastroch M; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany.; Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München.; Department of Molecular Biosciences, The Wenner-Gren Institute, The Arrhenius Laboratories F3, Stockholm University, SE-106 91 Stockholm, Sweden., Haendeler J; Institute for Clinical Chemistry, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.; IUF - Leibniz Research Institute for Environmental Medicine, Heisenberg Group - Environmentally-induced Cardiovascular Degeneration, Düsseldorf, Germany., Fischer JW; Institute of Pharmacology and Clinical Pharmacology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Publikováno v:
Nature metabolism [Nat Metab] 2019 May; Vol. 1 (5), pp. 546-559. Date of Electronic Publication: 2019 Apr 22.
Autor:
Jelenik T; Institute for Clinical Diabetology, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Dille M; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Müller-Lühlhoff S; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Kabra DG; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Zhou Z; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Binsch C; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Hartwig S; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Lehr S; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Chadt A; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Peters EMJ; Justus-Liebig-University, Department of Psychosomatics and Psychotherapy, Psychoneuroimmunology Laboratory, Gießen, Germany., Kruse J; Justus-Liebig-University, Department of Psychosomatics and Psychotherapy, Psychoneuroimmunology Laboratory, Gießen, Germany., Roden M; Institute for Clinical Diabetology, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany., Al-Hasani H; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany. Electronic address: hadi.al-hasani@ddz.uni-duesseldorf.de., Castañeda TR; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Medical Faculty, Heinrich Heine University, Leibniz Center for Diabetes Research, Düsseldorf, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Publikováno v:
Molecular metabolism [Mol Metab] 2018 Oct; Vol. 16, pp. 126-138. Date of Electronic Publication: 2018 Jun 20.