Serotonin as a Mitogen in the Gastrointestinal Tract: Revisiting a Familiar Molecule in a New Role

Autor: Pooja A Shah, Matthew P. Shaughnessy, Robert A. Cowles, Christine J. Park

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1093-1104 (2021)

Serotonin signaling is ubiquitous in the gastrointestinal (GI) system, where it acts as a neurotransmitter in the enteric nervous system (ENS) and influences intestinal motility and inflammation. Since its discovery, serotonin has been linked to cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2008b914a0a533134c8ceb6489e88004
https://doi.org/10.1016/j.jcmgh.2021.05.008

Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis

Autor: Laura Rossi, Waliul I. Khan, Jean-Eric Ghia, Steve P. Bernier, Stephen M. Collins, Emmanuel Denou, Suhrid Banskota, Md. Sharif Shajib, Michelle E. Fontes, Huaqing Wang, Yun Han Kwon, Michael G. Surette

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 709-728 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme for 5-HT synthesis in EC cells. Accumulating evidence sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d7b958a4788fee643381de67358945
https://doi.org/10.1016/j.jcmgh.2019.01.004

Social inequalities in health in nonhuman primates

Autor: Carol A. Shively, Stephen M. Day

Publikováno v: Social Inequalities in Health in Nonhuman Primates
Neurobiology of Stress
Neurobiology of Stress, Vol 1, Iss C, Pp 156-163 (2015)

Overall health has been linked to socioeconomic status, with the gap between social strata increasing each year. Studying the impact of social position on health and biological functioning in nonhuman primates has allowed researchers to model the hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d781d24ca7140749d5e1189842090362
https://doi.org/10.1016/j.ynstr.2014.11.005

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Pathogenic Mechanisms of Pulmonary Arterial Hypertension: Homeostasis Imbalance of Endothelium-Derived Relaxing and Contracting Factors.

Autor: Zhu J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Yang L; College of Veterinary Medicine, Northwest A&F University, Yangling, China., Jia Y; College of Veterinary Medicine, Northwest A&F University, Yangling, China., Balistrieri A; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Fraidenburg DR; Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA., Wang J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Tang H; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Yuan JX; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA.

Publikováno v: JACC. Asia [JACC Asia] 2022 Dec 15; Vol. 2 (7), pp. 787-802. Date of Electronic Publication: 2022 Dec 15 (Print Publication: 2022).