Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Toyotaka Ishibashi"'
Autor:
Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang, Yuanliang Zhai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The replisome that replicates the eukaryotic genome consists of at least three engines: the Cdc45-MCM-GINS (CMG) helicase that separates duplex DNA at the replication fork and two DNA polymerases, one on each strand, that replicate the unwou
Externí odkaz:
https://doaj.org/article/8b0eab14f8004ba38ff7b0abfe5819c5
Autor:
Taobo Hu, Jingjing Li, Mengping Long, Jinbo Wu, Zhen Zhang, Fei Xie, Jin Zhao, Houpu Yang, Qianqian Song, Sheng Lian, Jiandong Shi, Xueyu Guo, Daoli Yuan, Dandan Lang, Guoliang Yu, Baosheng Liang, Xiaohua Zhou, Toyotaka Ishibashi, Xiaodan Fan, Weichuan Yu, Depeng Wang, Yang Wang, I-Feng Peng, Shu Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Structural variations (SVs) are common genetic alterations in the human genome that could cause different phenotypes and diseases, including cancer. However, the detection of structural variations using the second-generation sequencing wa
Externí odkaz:
https://doaj.org/article/f3cfd0353e8c43efa7d9dc83c739140b
Autor:
Manchuta Dangkulwanich, Toyotaka Ishibashi, Shixin Liu, Maria L Kireeva, Lucyna Lubkowska, Mikhail Kashlev, Carlos J Bustamante
Publikováno v:
eLife, Vol 2 (2013)
During transcription elongation, RNA polymerase has been assumed to attain equilibrium between pre- and post-translocated states rapidly relative to the subsequent catalysis. Under this assumption, recent single-molecule studies proposed a branched B
Externí odkaz:
https://doaj.org/article/7fa5950ab09845afa9ad63fb17e24c40
Autor:
Dongbo Ding, Matthew Y.H. Pang, Mingxi Deng, Thi Thuy Nguyen, Xulun Sun, Zhichun Xu, Yingyi Zhang, Yuanliang Zhai, Yan Yan, Toyotaka Ishibashi
During spermatogenesis, multiple testis-specific histone variants are involved in the dynamic chromatin transitions. H2BFWT is a primate testis-specific H2B variant with hitherto unclear functions, and SNPs of H2BFWT are closely associated with male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073066c6395173ff995269b6667e9eba
https://doi.org/10.1101/2022.07.20.500751
https://doi.org/10.1101/2022.07.20.500751
Autor:
Jiandong Shi, Dandan Lang, I-Feng Peng, Xiao-Hua Zhou, Houpu Yang, Xiaodan Fan, Jinbo Wu, Daoli Yuan, Zhen Zhang, Yang Wang, Jingjing Li, Xueyu Guo, Jin Zhao, Qianqian Song, Fei Xie, Shen Lian, Taobo Hu, Shu Wang, Mengping Long, Toyotaka Ishibashi, Guoliang Yu, Baosheng Liang, Depeng Wang, Weichuan Yu
Publikováno v:
Frontiers in Cell and Developmental Biology. 10
Background: Structural variations (SVs) are common genetic alterations in the human genome that could cause different phenotypes and various diseases including cancer. However, the detection of structural variations using the second-generation sequen
Autor:
Thi Thuy Nguyen, Dongbo Ding, Matthew Y. H. Pang, Mingxi Deng, Zhichun Xu, Yingyi Zhang, Yuanliang Zhai, Yan Yan, Toyotaka Ishibashi
Publikováno v:
SSRN Electronic Journal.
Autor:
Ka Chun Jonathan Kwan, Yihang Jing, Zheng Liu, Xiang David Li, Dongbo Ding, Toyotaka Ishibashi, Gaofei Tian
Publikováno v:
Nucleic Acids Research
Posttranslational modifications (PTMs) of histones represent a crucial regulatory mechanism of nucleosome and chromatin dynamics in various of DNA-based cellular processes, such as replication, transcription and DNA damage repair. Lysine succinylatio
Autor:
Xin Yi Tan, Junshi Li, Justin W.C. Leung, Kirk West, Cheng-han Yu, Shirley M.-H. Sy, Chao Dong, Toyotaka Ishibashi, Michael S.Y. Huen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Cells avoid clashes between DNA repair machineries and the transcription apparatus by temporary halting gene expression in the vicinity of DNA double-strand breaks (DSBs), an emerging DNA damage response (DDR) that underlies genome integ
Autor:
Dongbo Ding, Qing Li, Maggie Zi-Ying Chow, Kui Ming Chan, Junhong Han, Michael S.Y. Huen, Yuchen Zhang, Toyotaka Ishibashi, Du Yang, Tze Zhen Evangeline Kang, Yi Ching Esther Wan, Lina Zhu, Xin Wang, Jiaxian Liu, Zongli Zheng, Ajay Goel, Tsz Chui Sophia Leung, Chengmin Qian, Jitian Zhang, Xulun Sun
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-4 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Autor:
An Yanru, Toyotaka Ishibashi, Sophia T C Leung, Wenjin Shi, Christopher J. Nelson, Mengping Long, Xulun Sun, Manjinder S. Cheema, Nicol Macpherson, Dongbo Ding, Juan Ausió, Yan Yan
Publikováno v:
Nucleic Acids Research
Histone variants, present in various cell types and tissues, are known to exhibit different functions. For example, histone H3.3 and H2A.Z are both involved in gene expression regulation, whereas H2A.X is a specific variant that responds to DNA doubl