Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Toyoharu Oba"'
Autor:
Takanobu Nagata, Hideo Yasukawa, Sachiko Kyogoku, Toyoharu Oba, Jinya Takahashi, Shoichiro Nohara, Tomoko Minami, Kazutoshi Mawatari, Yusuke Sugi, Koutatsu Shimozono, Sylvain Pradervand, Masahiko Hoshijima, Hiroki Aoki, Yoshihiro Fukumoto, Tsutomu Imaizumi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127942 (2015)
Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotect
Externí odkaz:
https://doaj.org/article/8d05709fc4874091845e44d11e40e62e
Autor:
Atsuko Tahara, Munehisa Bekki, Akihiro Honda, Toshi Abe, Nobuhiro Tahara, Shoko Maeda-Ogata, Yoichi Sugiyama, Toyoharu Oba, Sachiyo Igata, Yoshihiro Fukumoto
Publikováno v:
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9371f8773255f03fb195f09f4733c6c
https://pubmed.ncbi.nlm.nih.gov/34244965
https://pubmed.ncbi.nlm.nih.gov/34244965
Autor:
Hisashi Kai, Jinya Takahashi, Yoshihiro Fukumoto, Shoichiro Nohara, Sachiyo Igata, Tomoko Minami, Sachiko Kyogoku, Hideo Yasukawa, Takanobu Nagata, Hiroki Aoki, Hideki Ohshima, Michihide Nishihara, Yoshiko Iwamoto, Toyoharu Oba, Makoto Takano, Kazutoshi Mawatari, Yusuke Sugi, Hidehiro Matsuoka, Tsutomu Imaizumi
Publikováno v:
Circulation Journal. 79:1557-1567
Background Remote ischemic preconditioning (RIPC) induced by transient limb ischemia is a powerful innate mechanism of cardioprotection against ischemia. Several described mechanisms explain how RIPC may act through neural pathways or humoral factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335bc562301a9f35f68edc931a54f7e6
https://doi.org/10.1253/circj.cj-14-1171
https://doi.org/10.1253/circj.cj-14-1171
Autor:
Michihide Nishihara, Naoki Itaya, Naohiro Yoshikawa, Takanobu Nagata, Daiki Akagaki, Hanae Yoshimura, Hideki Ohshima, Toyoharu Oba, Takafumi Ueno, Eita Kumagai, Yoshihiro Fukumoto
Publikováno v:
The Kurume medical journal. 63(1.2)
Because of the protective effect of estrogen for atherosclerosis, the prevalence of acute coronary syndrome in women before menopause is low. We report a rare case of unstable angina in a young Japanese female who had a history of cigarette smoking a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6eb0782eb806c7715259e49e2bc044
https://pubmed.ncbi.nlm.nih.gov/28090005
https://pubmed.ncbi.nlm.nih.gov/28090005
Publikováno v:
JAK-STAT. 1:234-240
The suppressors of cytokine signaling (SOCS) family of proteins are cytokine-inducible inhibitors of Janus kinase (JAK)-signal transducer and activator of the transcription (STAT) signaling pathways. Among the family, SOCS1 and SOCS3 potently suppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0faf4f242060c7d83739bec098ac059e
https://doi.org/10.4161/jkst.22435
https://doi.org/10.4161/jkst.22435
Autor:
Kei-ichiro Nakamura, Kirk U. Knowlton, Tomoko Minami, Toshitaka Yajima, Takanobu Nagata, Masahiko Hoshijima, Sachiko Kyogoku, Hideki Ohshima, Ken-ichiro Sasaki, Toyoharu Oba, Dongchon Kang, Hideo Yasukawa, Daisuke Fukui, Tsutomu Imaizumi, Kazutoshi Mawatari, Nobuyoshi Futamata
Publikováno v:
Journal of the American College of Cardiology. 59(9):838-852
Objectives The study investigated the role of myocardial suppressor of cytokine signaling-3 (SOCS3), an intrinsic negative feedback regulator of the janus kinase and signal transducer and activator of transcription (JAK-STAT) signaling pathway, in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5939a26f35a2e6f593a00f3531a2a81f
Autor:
Tsutomu Imaizumi, Minori Mizoguchi, Kazutoshi Mawatari, Norihiro Kodama, Atsuko Tahara, Toyoharu Oba, Masatoshi Ishibashi, Yoshikazu Nitta, Hayato Kaida, Naofumi Hayabuchi, Haruhito Harada, Nobuhiro Tahara, Hisao Ikeda, Hideo Yasukawa, Sho-ichi Yamagishi
Publikováno v:
JACC: Cardiovascular Imaging. 4:1110-1118
Objectives: The aim of this study was to compare the effect of pioglitazone, an insulin sensitizer, with glimepiride, an insulin secretagogue, on atherosclerotic plaque inflammation by using serial...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864a27be57860f8d687134d6256bcb43
https://doi.org/10.1016/j.jcmg.2011.08.007
https://doi.org/10.1016/j.jcmg.2011.08.007
Reduction and activation of circulating dendritic cells in patients with decompensated heart failure
Autor:
Hideo Yasukawa, Daisuke Fukui, Hisashi Kai, Mitsuhisa Koga, Nobuyoshi Futamata, Kazuhisa Mawatari, Nobutaka Nagata, Toyoharu Oba, Sachiko Kyougoku, Yusuke Sugi, Tsutomu Imaizumi
Publikováno v:
International Journal of Cardiology. 147:258-264
Dendritic cells (DCs) are the most potent antigen-presenting cells and play a central role in initiating the primary immune response. Although increasing evidence supports immune-mediated inflammation plays an important role in the pathophysiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b21d39bed6a4f1b48fd4d27addd461d
https://doi.org/10.1016/j.ijcard.2009.09.524
https://doi.org/10.1016/j.ijcard.2009.09.524
Publikováno v:
Journal of the American College of Cardiology. 63(6):560-562
Malignant ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation (VF), are leading causes of total and cardiovascular mortality [(1,2)][1]. Sudden cardiac death resulting from these ventricular arrhythmias represents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2af6cea46ebdb8184ef4fea98dc101
Autor:
Shoichiro Nohara, Hideo Yasukawa, Toyoharu Oba, Takanobu Nagata, Jinya Takahashi, Koutatsu Shimozono, Tomoko Minami, Hideki Ohshima, Sachiko Kyogoku, Daisuke Fukui, Kazutoshi Mawatari, Yusuke Sugi, Yoshihiro Fukumoto
Publikováno v:
Circulation. 132
Introduction: Suppressor of cytokine signaling-3 (SOCS3) is a cytokine-inducible negative regulator of JAK-STAT signaling pathway. Cardiac-specific SOCS3 deficient mice (SOCS3-CKO) spontaneously develop cardiac dysfunction with advanced age. Hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c0543b52b70d4d139aaa94c5925fda
https://doi.org/10.1161/circ.132.suppl_3.18442
https://doi.org/10.1161/circ.132.suppl_3.18442