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pro vyhledávání: '"Toyanji Joseph Punchaichira"'
Autor:
Anirban Mukhopadhyay, Prachi Kukshal, Triptish Bhatia, Toyanji Joseph Punchaichira, B.K. Thelma, Smita N. Deshpande
Publikováno v:
J Psychopharmacol
Background:Dopamine-β-hydroxylase (DBH, EC 1.14.17.1), which converts dopamine to norepinephrine, is a candidate gene in neuropsychiatric diseases.Aim:To assess the effect of regulatory variants in DBH on schizophrenia and its endophenotypes –cogn
Publikováno v:
Pharmacogenetics and Genomics. 26:311-323
OBJECTIVE Dopamine-β-hydroxylase (DBH), an enzyme that converts dopamine into norepinephrine, is a drug target in cardiovascular and neuropsychiatric disorders. We aimed to identify functional variants in this gene by deep sequencing and enzyme phen
Publikováno v:
Neurochemical research. 43(12)
Dopamine-β-hydroxylase (DBH, EC 1.14.17.1) is an enzyme with implications in various neuropsychiatric and cardiovascular diseases and is a known drug target. There is a dearth of cost effective and fast method for estimation of activity of this enzy
Autor:
Sanjay Kumar Dey, Anirban Mukhopadhyay, B.K. Thelma, Suman Kundu, Toyanji Joseph Punchaichira
Publikováno v:
Neurogenetics. 18(3)
Dopamine-β-hydroxylase (DBH, EC 1.14.17.1), an oxido-reductase that catalyses the conversion of dopamine to norepinephrine, is largely expressed in sympathetic neurons and adrenal medulla. Several regulatory and structural variants in DBH associated