Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Towa Sasakura"'
Autor:
Norikazu Yabuta, Chie Ota, Towa Sasakura, Yoko Naito, Daisuke Okuzaki, Kohshiro Fukushima, Hiroshi Nojima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 p
Externí odkaz:
https://doaj.org/article/d823cb5749da467494f672201e541b3e
Autor:
Minami A Sakurai, Yuki Ozaki, Daisuke Okuzaki, Yoko Naito, Towa Sasakura, Ayumi Okamoto, Hiroe Tabara, Takao Inoue, Man Hagiyama, Akihiko Ito, Norikazu Yabuta, Hiroshi Nojima
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100124 (2014)
Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostat
Externí odkaz:
https://doaj.org/article/655f82c6fc96407fb4514f6df014720a
Autor:
Yoko Naito, Norikazu Yabuta, Towa Sasakura, Kohshiro Fukushima, Moe Fukuzawa, Ayumi Okamoto, Satomi Mukai, Masami Nozaki, Gregory D. Longmore, Hiroshi Nojima
Publikováno v:
Oncotarget
Cancer stem cells (CSCs), which play important roles in tumor initiation and progression, are resistant to many types of therapies. However, the regulatory mechanisms underlying CSC-specific properties, including self-renewal, are poorly understood.
Autor:
Hiroshi Nojima, Daisuke Okuzaki, Norikazu Yabuta, Yoko Naito, Chie Ota, Towa Sasakura, Kohshiro Fukushima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 phosphoryl
Autor:
Hiroshi Nojima, Towa Sasakura, Hiroyuki Shimizu, Kohshiro Fukushima, Toshihiro Uchihashi, Yusuke Yabuno, Mikihiko Kogo, Norikazu Yabuta, Kaori Ota, Yoko Naito
Publikováno v:
Cell Cycle
Clathrin regulates mitotic progression, in addition to membrane trafficking. However, the detailed regulatory mechanisms of clathrin during mitosis remain elusive. Here, we demonstrate novel regulation of clathrin during mitotic phase of the cell cyc
Autor:
Yoko Naito, Daisuke Okuzaki, Norikazu Yabuta, Kaori Ota, Yukihiro Nishikawa, Shouichi Ohno, Kosuke Torigata, Towa Sasakura, Kohshiro Fukushima, Eiichi Morii, Toshihiro Uchihashi, Jun-ichiro Ikeda, Daisaku Miura, Takashi Kasama, Yorika Kato, Hiroshi Nojima, Mian Wang
Publikováno v:
Scientific Reports
Cyclin G1 (CycG1) and Cyclin G2 (CycG2) play similar roles during the DNA damage response (DDR), but their detailed roles remain elusive. To investigate their distinct roles, we generated knockout mice deficient in CycG1 (G1KO) or CycG2 (G2KO), as we
Autor:
Yoko Naito, Hiroe Tabara, Ayumi Okamoto, Norikazu Yabuta, Towa Sasakura, Takao Inoue, Yuki Ozaki, Daisuke Okuzaki, Man Hagiyama, Minami A. Sakurai, Hiroshi Nojima, Akihiko Ito
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e100124 (2014)
PLoS ONE, Vol 9, Iss 6, p e100124 (2014)
Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostat