Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tove Sivik"'
Autor:
Tove Sivik, Cecilia Gunnarsson, Tommy Fornander, Bo Nordenskjöld, Lambert Skoog, Olle Stål, Agneta Jansson
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40568 (2012)
INTRODUCTION: 17β-Hydroxysteroid dehydrogenases (17βHSDs) are important enzymes regulating the pool of bioactive steroids in the breast. The current study was undertaken in order to evaluate implications of 17βHSD14 in breast cancer, measuring 17
Externí odkaz:
https://doaj.org/article/a0a13b67e2044dd9b23c720ee7600f66
Publikováno v:
Breast Cancer Research and Treatment
To investigate the expression levels of CXCL10 and CXCR3 in tumors from breast cancer patients randomized to adjuvant tamoxifen treatment or no endocrine treatment, in order to further study the connection to prognosis and prediction of tamoxifen tre
Publikováno v:
Hormone and Metabolic Research. 44:949-956
17βHSD enzymes catalyze the stereospecific oxidation/reduction at carbon 17β of androgens and estrogens, and are important players in intracrine sex hormone synthesis. The biological relevance of 17βHSD14, first named retSDR3, is largely unknown.
Autor:
Olle Stål, Bo Nordenskjöld, Tove Sivik, Agneta Jansson Jansson, Tommy Fornander, Erik Hilborn, A Kot, Lambert Skoog
Publikováno v:
Cancer Research. 71:P1-06
Background: CXCL10 is a chemokine with chemo attractant properties which signals through G protein-coupled receptor CXCR3. At least two reported isoforms exists; CXCR3-A and CXCR3-B. CXCL10 is involved in the recruitment of leucocytes, immune modulat
Autor:
Agneta Jansson, Tove Sivik
Publikováno v:
Biochemical and biophysical research communications. 422(1)
The use of combined hormone replacement therapy (HAT) with oestrogens and progestins in postmenopausal women has been associated with an increased risk for developing breast cancer. The reasons are not fully understood, but influence of HRT on endoge
Autor:
Agneta Jansson, Bo Nordenskjöld, Tommy Fornander, Tove Sivik, Lambert Skoog, Olle Stål, Cecilia Gunnarsson
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40568 (2012)
PLoS ONE
PLoS ONE
INTRODUCTION: 17β-Hydroxysteroid dehydrogenases (17βHSDs) are important enzymes regulating the pool of bioactive steroids in the breast. The current study was undertaken in order to evaluate implications of 17βHSD14 in breast cancer, measuring 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e6f5212bfb0edd75b8245fd86bf956
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-80247
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-80247
Publikováno v:
Hormone molecular biology and clinical investigation. 3(1)
The 17β-hydroxysteroid dehydrogenase enzymes modify the availability of potent sex steroids and have thus attracted interest in the study of several steroid-dependent pathologies including breast, endometrial and prostate cancers. An increased aware
Publikováno v:
Cancer research. 66(23)
Estrogens have an important role in the progression of breast cancer. The 17β-hydroxysteroid dehydrogenase (17HSD) family has been identified to be of significance in hormone-dependent tissues. 17HSD1 and 17HSD2 are the main 17HSD enzymes involved i
Autor:
Bo Nordenskjöld, Lambert Skoog, Olle Stål, Agneta Jansson, Tommy Fornander, Agnieszka Kot, Tove Sivik
Publikováno v:
Cancer Research. 71:3142-3142
Chemokines are small cytokine-like secreted proteins with chemoattractant properties which function in the recruitment of leucocytes into inflamed tissue. Besides well studied roles in the immune system, chemokines and their receptors have also been
Publikováno v:
Cancer Research. 69:2015-2015
Background: Peripheral sex steroid synthesis in target organs from adrenally derived steroid precursors is believed to be an ongoing event throughout life, but becomes exceedingly important as the gonadal sources of sex steroids cease, as is the case