Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tova Zinman"'
Autor:
Vladimir Shneyvays, Asher Shainberg, Tova Zinman, Rachel Lubart, Ahuva Isaac, Elicheva Hochauser, Harry Friedmann, Ronit Lavi
Publikováno v:
Lasers in Surgery and Medicine. 42:473-480
Background and Objective Light in the visible and near infrared region stimulates various cellular processes, and thus has been used for therapeutic purposes. One of the proposed mechanisms is based on cellular production of reactive oxygen species (
Publikováno v:
Cell Calcium. 43:324-333
The involvement of nitric oxide (NO) in the late phase of ischemic preconditioning is well established. However, the role of NO as a trigger or mediator of “classic preconditioning” remains to be determined. The present study was designed to inve
Publikováno v:
Journal of Molecular and Cellular Cardiology. 39:149-158
Mitochondrial disorder is characteristic of many myocardial injuries such as endotoxemia, shock, acidosis, ischemia/reperfusion, and others. The goal of possible therapy is to increase ATP production. Derivatives of vitamins K may be a potent electro
Autor:
Mordechai Manoach, Tova Zinman, Vladimir Shneyvays, Asher Shainberg, Shay Moshel, Weismann P, Liaman K. Mamedova, Sawa Kostin, Narcis Tribulova
Publikováno v:
Journal of Molecular Histology. 35:463-470
This study examined whether triiodo-L-thyronine (T3) affects the expression of the major intercellular channel protein, connexin-43, and contractile protein alpha-sarcomeric actin. Cultured cardiomyocytes from newborn rats were treated on day three i
Publikováno v:
Biochemical and Biophysical Research Communications. 300:23-28
The changes measured in intracellular fluorescein fluorescence polarization (IFFP) are used as a new tool for tracing cytoplasmic effects during contractile cycles of cardiac myocytes (1-2-day-old rat hearts), in addition to the established Ca(2+) mo
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:1249-1261
Adenosine exerts a marked protective effect on the heart during cardiac ischemia. This protection is mediated by binding to the A 1 and A 3 subtypes of adenosine receptor (A 1 R and A 3 R, respectively). The objective of the present study was to inve
Autor:
V. Shneyvays, Asher Shainberg, Hermann Nawrath, Tova Zinman, Kenneth A. Jacobson, Ahuva Isaac, A H Li
Publikováno v:
Experimental Cell Research. 257:111-126
The purpose of the present study was to investigate the mechanisms involved in the induction of apoptosis in newborn cultured cardiomyocytes by activation of adenosine (ADO) A3 receptors and to examine the protective effects of beta-adrenoceptors. Th
Autor:
Narcisa Tribulova, Dalia Varon, I. Imanaga, Mordechai Manoach, Asher Shainberg, A Isaack, Tova Zinman
Publikováno v:
Life Sciences. 65:PL273-PL279
These results support our hypothesis that class III compounds, with a positive inotropic effect, increase intercellular coupling and synchronization, mainly by preventing intracellular Ca overload. They act as defibrillating compound, similar to cAMP
Autor:
Tova Zinman, Bilha Fischer, Irit Rutman-Halili, Asher Shainberg, Revital Yefidoff, Kenneth A. Jacobson, Dan Thomas Major, Valadimir Shneyvays
Publikováno v:
Journal of Medicinal Chemistry. 42:2685-2696
The design and synthesis of "mini-nucleotides", based on a xanthine-alkyl phosphate scaffold, are described. The physiological effects of the new compounds were evaluated in rat cardiac cell culture regarding Ca(2+) elevation and contractility. The r
Publikováno v:
Bioelectromagnetics. 33(8)
The purpose of this study was to determine the effect of extremely low frequency and weak magnetic fields (WMF) on cardiac myocyte Ca 2þ transients, and to explore the involvement of potassium channels under the WMF effect. In addition, we aimed to