Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tova Rahn"'
Autor:
Shakur, Yasmin, Holst, Lena Stenson, Landstrom, Tova Rahn, Movsesian, Matthew, Degerman, Eva, Manganiello, Vincent
Publikováno v:
In Progress in Nucleic Acid Research and Molecular Biology 2000 66:241-277
Publikováno v:
Biochemical Journal. 346:337-343
We have used murine 3T3-L1 cells, which differentiate in culture and acquire morphological and biochemical features of mature adipocytes, as a model for studying the expression of cyclic-nucleotide phosphodiesterase (PDE) 3B activity, protein and mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a8235a611719b31fec7d5d80bf7214
https://doi.org/10.1042/bj3460337
https://doi.org/10.1042/bj3460337
Autor:
Faiyaz Ahmad, Guang Gao, Ling Mei Wang, Tova Rahn Landstrom, Eva Degerman, Jacalyn H. Pierce, Vincent C. Manganiello
Publikováno v:
The Journal of Immunology. 162:4864-4875
In FDCP2 myeloid cells, IL-4 activated cyclic nucleotide phosphodiesterases PDE3 and PDE4, whereas IL-3, granulocyte-macrophage CSF (GM-CSF), and phorbol ester (PMA) selectively activated PDE4. IL-4 (not IL-3 or GM-CSF) induced tyrosine phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c24de4efe6804b0787849f362ddc80
https://doi.org/10.4049/jimmunol.162.8.4864
https://doi.org/10.4049/jimmunol.162.8.4864
Publikováno v:
Endocrinology. 139:219-227
Insulin stimulation of adipocytes results in serine phosphorylation/activation of phosphodiesterase 3B (PDE 3B) and activation of a kinase that phosphorylates PDE 3B in vitro, key events in the antilipolytic action of this hormone. We have investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf9d781a99bb33eae3b24fb02a77df9
https://doi.org/10.1210/endo.139.1.5693
https://doi.org/10.1210/endo.139.1.5693
Autor:
Svante Resjö, Jonny Wijkander, Per Belfrage, Eva Degerman, Isabelle Castan, Vincent C. Manganiello, Tova Rahn, Lena Stenson Holst
Publikováno v:
Journal of Biological Chemistry. 272:21520-21526
Protein kinase B (PKB) (also referred to as RAC/Akt kinase) has been shown to be controlled by various growth factors, including insulin, using cell lines and transfected cells. However, information is so far scarce regarding its regulation in primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3cea27645b34e2d242ca5893ea9cf7b
https://doi.org/10.1074/jbc.272.34.21520
https://doi.org/10.1074/jbc.272.34.21520
Cyclic nucleotide phosphodiesterases (PDEs) include a large group of structurally related enzymes that are responsible for the hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). These enzymes belong to at l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af1e2bd1a09dad623ef8c2335d1f15a
https://doi.org/10.1385/1-59259-231-7:167
https://doi.org/10.1385/1-59259-231-7:167
Autor:
Tova Rahn Landström, Cecilia Holm, Lena Stenson Holst, Eva Degerman, Jie Mei, David N. Brindley, Vincent C. Manganiello
Publikováno v:
Diabetes. 51(3)
Cyclic nucleotide phosphodiesterase (PDE) 3B plays an important role in the antilipolytic action of insulin and, thereby, the release of fatty acids from adipocytes. Increased concentrations of circulating fatty acids as a result of elevated or unres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a91495c3cb2fcb4bd55b650f098a634
https://pubmed.ncbi.nlm.nih.gov/11872660
https://pubmed.ncbi.nlm.nih.gov/11872660
Autor:
Eva Degerman, Tova Rahn Landström, Faiyaz Ahmad, Vincent C. Manganiello, Li-Tzu Wang, L N Cong, M J Quon, Jacalyn H. Pierce, Lena Stenson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 164(9)
Wild-type (F/B), constitutively active (F/B*), and three kinase-inactive (F/Ba−, F/Bb−, F/Bc−) forms of Akt/protein kinase B (PKB) were permanently overexpressed in FDCP2 cells. In the absence of insulin-like growth factor-1 (IGF-1), activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6227bfb2db5c63ce8e979e75a8c2e97c
https://pubmed.ncbi.nlm.nih.gov/10779773
https://pubmed.ncbi.nlm.nih.gov/10779773
Autor:
Vincent C. Manganiello, Eva Degerman, Cristina M. Rondinone, Ulf P. Smith, Tova Rahn, Eugenia Carvalho
Publikováno v:
The Journal of biological chemistry. 275(14)
Phosphatidylinositol 3-kinase mediates several actions of insulin including its antilipolytic effect. This effect is elicited by the insulin-stimulated serine phosphorylation and activation of cGMP-inhibited phosphodiesterase (PDE3B). In human adipoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc6550117094e6d2f3f182474f562ff
https://pubmed.ncbi.nlm.nih.gov/10744689
https://pubmed.ncbi.nlm.nih.gov/10744689
Autor:
Vincent C. Manganiello, Tova Rahn Landström, Lena Stenson Holst, Eva Degerman, Matthew A. Movsesian, Yasmin Shakur
Publikováno v:
Progress in Nucleic Acid Research and Molecular Biology ISBN: 9780125400664
Publisher Summary This chapter discusses some general information about cyclic nucleotide phosphodiesterases (PDEs). It also discusses the PDE3 gene family, emphasizing the molecular biology, structure/function relationships, and cellular regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf8425e953c2537d96ed5873da1b6a7
https://doi.org/10.1016/s0079-6603(00)66031-2
https://doi.org/10.1016/s0079-6603(00)66031-2