Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid nanoparticles.

Autor: Degtev D; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden. dmitrii.degtev@astrazeneca.com., Bravo J; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA., Emmanouilidi A; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Zdravković A; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Choong OK; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Liz Touza J; Translational Genomics, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Selfjord N; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Weisheit I; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Francescatto M; Quantitative Biology, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Akcakaya P; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Porritt M; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden., Maresca M; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden. marcello.maresca@astrazeneca.com., Taylor D; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA. dtaylor@utexas.edu.; Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, 78712, USA. dtaylor@utexas.edu.; LIVESTRONG Cancer Institutes, Dell Medical School, Austin, TX, 78712, USA. dtaylor@utexas.edu., Sienski G; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden. grzegorz.sienski@astrazeneca.com.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 07; Vol. 15 (1), pp. 9173. Date of Electronic Publication: 2024 Nov 07.

When Space and Time Matter in Environmental Injustice: A Bayesian Analysis of the Association between Socio-economic Disadvantage and Air Pollution in Greater Mexico City.

Autor: Lome-Hurtado A; Facultad de Ciencias Económicas y Empresariales, Universidad Panamericana, Álvaro del Portillo 49, Zapopan, Jalisco, 45010, Mexico. alexlome@up.edu.mx., Touza J; Department of Environment and Geography & York Environmental Sustainability Institute, University of York, Wentworth Way, University of York, York, YO10 5NG, United Kingdom., White PCL; Department of Environment and Geography & York Environmental Sustainability Institute, University of York, Wentworth Way, University of York, York, YO10 5NG, United Kingdom., McClean CJ; Department of Environment and Geography & York Environmental Sustainability Institute, University of York, Wentworth Way, University of York, York, YO10 5NG, United Kingdom.

Publikováno v: Environmental management [Environ Manage] 2024 Mar; Vol. 73 (3), pp. 657-667. Date of Electronic Publication: 2023 Nov 06.

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Incorporating fire-smartness into agricultural policies reduces suppression costs and ecosystem services damages from wildfires.

Autor: Lecina-Diaz J; Technical University of Munich, TUM School of Life Sciences, Ecosystem Dynamics and Forest Management Group, Hans-Carl-von-Carlowitz-Platz 2, 85354, Freising, Germany; CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Campus de Vairão, Universidade do Porto, 4485-661, Vairão, Portugal; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, 4485-661, Vairão, Portugal. Electronic address: judit.lecina@tum.de., Chas-Amil ML; Department of Quantitative Economics, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain., Aquilué N; Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Ctra. St. Llorenç de Morunys km 2, Solsona, 25280, Spain; Centre for Forest Research (CFR), Université du Québec à Montréal (UQAM), C.P. 8888, succ. Centre-Ville, Montréal, QC, H3C 3P8, Canada., Sil Â; CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Campus de Vairão, Universidade do Porto, 4485-661, Vairão, Portugal; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, 4485-661, Vairão, Portugal; CITAB - Centro de Investigação e de Tecnologias Agro-Ambientais e Biológicas, Universidade de Trás-os-Montes e Alto Douro, 5001-801, Portugal; CIMO - Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253, Bragança, Portugal., Brotons L; Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Ctra. St. Llorenç de Morunys km 2, Solsona, 25280, Spain; CREAF, Cerdanyola del Vallès, Barcelona, Spain; CSIC, Cerdanyola del Vallès, Barcelona, Spain., Regos A; CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Campus de Vairão, Universidade do Porto, 4485-661, Vairão, Portugal; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, 4485-661, Vairão, Portugal; Centre de Ciència i Tecnologia Forestal de Catalunya (CTFC), Ctra. St. Llorenç de Morunys km 2, Solsona, 25280, Spain; Departamento de Zooloxía, Xenética e Antropoloxía Física, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Touza J; Department of Environment and Geography and York Environmental Sustainability Institute, University of York, Heslington, York, YO10 5NG, UK.

Publikováno v: Journal of environmental management [J Environ Manage] 2023 Jul 01; Vol. 337, pp. 117707. Date of Electronic Publication: 2023 Mar 28.

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