Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.

Autor: Truex NL; Department of Chemistry, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.; Department of Chemistry and Biochemistry, University of South Carolina; 631 Sumter St., Columbia, South Carolina, 29208, USA., Mohapatra S; Department of Materials Science and Engineering, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.; Machine Intelligence and Manufacturing Operations Group, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA., Melo M; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; 500 Main Street, Cambridge, Massachusetts 02142, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology; 400 Technology Square, Cambridge, Massachusetts 02139, USA., Rodriguez J; Department of Chemistry, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA., Li N; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; 500 Main Street, Cambridge, Massachusetts 02142, USA., Abraham W; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; 500 Main Street, Cambridge, Massachusetts 02142, USA., Sementa D; Department of Chemistry, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA., Touti F; Department of Chemistry, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute; Boston, Massachusetts, 02215, USA.; Harvard Medical School; Boston, Massachusetts, 02115, USA.; Broad Institute of MIT and Harvard; Cambridge, Massachusetts, USA.; Translational Immunogenomics Laboratory (TIGL), Dana-Farber Cancer Institute; Boston, Massachusetts, 02215, USA.; Department of Computer Science, Metropolitan College, Boston University; Boston, Massachusetts, USA.; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark; Lyngby, DK., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute; Boston, Massachusetts, 02215, USA.; Harvard Medical School; Boston, Massachusetts, 02115, USA.; Broad Institute of MIT and Harvard; Cambridge, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital; Boston, MA 02215, USA., Irvine DJ; Department of Materials Science and Engineering, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; 500 Main Street, Cambridge, Massachusetts 02142, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology; 400 Technology Square, Cambridge, Massachusetts 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.; Howard Hughes Medical Institute; 4000 Jones Bridge Rd, Chevy Chase, Maryland 20815, USA., Gómez-Bombarelli R; Department of Materials Science and Engineering, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA., Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; 500 Main Street, Cambridge, Massachusetts 02142, USA.; Broad Institute of MIT and Harvard; Cambridge, Massachusetts, USA.; Center for Environmental Health Sciences, Massachusetts Institute of Technology; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 26. Date of Electronic Publication: 2023 Sep 26.

Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors.

Autor: Cazanave SC; Glympse Bio Inc., Cambridge, MA 02138, USA., Warren AD; Glympse Bio Inc., Cambridge, MA 02138, USA., Pacula M; Glympse Bio Inc., Cambridge, MA 02138, USA., Touti F; Glympse Bio Inc., Cambridge, MA 02138, USA., Zagorska A; Gilead Sciences Inc., Foster City, CA 94404, USA., Gural N; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Huang EK; Glympse Bio Inc., Cambridge, MA 02138, USA., Sherman S, Cheema M; Glympse Bio Inc., Cambridge, MA 02138, USA., Ibarra S; Glympse Bio Inc., Cambridge, MA 02138, USA., Bates J; Gilead Sciences Inc., Foster City, CA 94404, USA., Billin AN; Gilead Sciences Inc., Foster City, CA 94404, USA., Liles JT; Gilead Sciences Inc., Foster City, CA 94404, USA., Budas GR; Gilead Sciences Inc., Foster City, CA 94404, USA., Breckenridge DG; Gilead Sciences Inc., Foster City, CA 94404, USA., Tiniakos D; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 7RU, UK., Ratziu V; Sorbonne Université, ICAN (Institute of Cardiometabolism And Nutrition), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne University, INSERM UMRS 1138 CRC, Paris 75013, France., Daly AK; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 7RU, UK., Govaere O; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 7RU, UK., Anstee QM; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 7RU, UK., Gelrud L; Bon Secours St Mary's Hospital, Richmond VA 23226, USA., Luther J; Liver Center, GI Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Chung RT; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA 30332, USA., Corey KE; Liver Center, GI Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Winckler W; Glympse Bio Inc., Cambridge, MA 02138, USA., Bhatia S; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kwong GA; Glympse Bio Inc., Cambridge, MA 02138, USA.; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA 30332, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2021 Oct 20; Vol. 13 (616), pp. eabe8939. Date of Electronic Publication: 2021 Oct 20.

Magnetogenic Probes for in vitro and in vivo detection of enzymes by magnetic resonance imaging

Autor: Touti, F., Gondrand, C., Canaple, L., Beuf, O., Hasserodt, J.

Publikováno v: 8èmes journées scientifiques du CLARA
8èmes journées scientifiques du CLARA, Mar 2013, Lyon, France

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::73e016c1a1f12990c5730d4b4b28c5b4
https://hal.archives-ouvertes.fr/hal-00855081

Hybrid Predictive Machine Learning Model for the Prediction of Immunodominant Peptides of Respiratory Syncytial Virus.

Autor: Bukhari, Syed Nisar Hussain¹ nisar@nielit.gov.in, Ogudo, Kingsley A.² kingsleyo@uj.ac.za

Publikováno v: Bioengineering (Basel). Aug2024, Vol. 11 Issue 8, p791. 16p.

In-solution enrichment identifies peptide inhibitors of protein-protein interactions.

Autor: Touti F; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. faycaltouti@gmail.com., Gates ZP; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Bandyopadhyay A; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Lautrette G; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. blp@mit.edu.; Koch Institute, Broad Institute of Harvard and MIT, Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. blp@mit.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2019 Apr; Vol. 15 (4), pp. 410-418. Date of Electronic Publication: 2019 Mar 18.