Efficacy and safety of CD24Fc in hospitalised patients with COVID-19: a randomised, double-blind, placebo-controlled, phase 3 study

Autor: Zheng, Pan, Liu, Yang, Devenport, Martin, Touomou, Raymond, Chou, Hung-Yen, Thakor, Jai, Khan, Imaan, Do, Nicole, Faragalla, Josephine, Hook, Andrea, Kern, Sarah, Ramos, Janira V., Ward, Jason, Chen, Jamie, Higson, John, Dam, Meena, Serkin, Dawn, Karloopia, Pooja, Moore, Wendy, Scofield, Mark, Childers, David Jeffery, Cantrell, Jeffrey S., Corgan, Millie, Li, Ella, Chen, Jian, Zhou, Xiang, Liu, Jing, Redvers-Higgins, Denise, Han, Hua, Hou, Jiyun, Pan, Yudi, Tucker, Karyn, Zhang, Xiaoyan, Kottilil, Shyamasundaran, Chua, Joel V., Husson, Jennifer, Narayanan, Shivakumar, Bran, Jaqueline, Lam, Ka Wing Joyce, Jeffrey, Alicia, Giddings, Olivia K., Pexa, Jennie, Becerra, Mario, Welker, James, Gray, Kathleen W., Richmond, Nicole, Nzelibe, Chukwuemeka, Malvestutto, Carlos D., Koletar, Susan, Sobhanie, Mahdee, Clark, Jan, Li, Zihai, Reynolds, Kelsi, Chakravarthy, Karthik, Weller, Kevin, Yusuf, Mohamed, Severing, Jennifer, Barley, Kelley, Pulido, Juan D., Fulton, Jennifer C., Gil, William, Jeanine, M.D., R.N., Richmond, Jones, Sandy, Clemmer, Kristina, Byrne, Dana, Pedroza, Lisa, Davidson, Emily Nicole, Logan, Amanda, Grant, Katie, Whitman, Eric D., Kessler, Jason, Roland, Robert, Stefiniw, Rosemary, Maurer, Molly, Geene, Salome, Buck, Christopher F., Connolly, Debra, Light, Patrice, Baviskar, Sunanda, Low, Yee Won, Michalski, Kyra, Giordano, Pamela, Chao, Jennifer, Williams, Michelle, Makkapati, Amulya, Catanzaro, Andrew T., Cohen, Jonathan B., Musbah, Mehad, Jaladanki, Pramila, Yuan, Ying, Rele, Shilpa, Stewart, Desirae, Lewis, Starlet, Sankar, Ian, Kasumba, Nabulungi, Biney, Kaylia, Hekmat, Elham, Lake, Jordan E., Akkanti, Bindu, Reimer-McAtee, Melissa J., Negret Hernandez, Marisel, Pulido, Juan D, Catanzaro, Andrew T, Malvestutto, Carlos D, Cohen, Jonathan B, Whitman, Eric D, Giddings, Olivia K, Lake, Jordan E, Chua, Joel V, He, Kun, Gates, Davis, Kaur, Amarjot

Publikováno v: In The Lancet Infectious Diseases May 2022 22(5):611-621

Efficacy and safety of CD24Fc in hospitalised patients with COVID-19: a randomised, double-blind, placebo-controlled, phase 3 study.

Autor: Welker J; Anne Arundel Research Institute, Annapolis, MD, USA., Pulido JD; Baptist Medical Center, Jacksonville, FL, USA., Catanzaro AT; Adventist HealthCare, Gaithersburg, MD, USA., Malvestutto CD; Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH USA., Li Z; Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH USA; Pelotonia Institute for Immuno-Oncology, The Ohio State University Wexner Medical Center, Columbus, OH USA., Cohen JB; Adventist HealthCare, Gaithersburg, MD, USA., Whitman ED; Atlantic Health System, Morristown, NJ, USA., Byrne D; Division of Infectious Diseases, Department of Medicine, Cooper Medical School of Rowan University, Cooper University Healthcare, Camden, NJ, USA., Giddings OK; University Hospitals, Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA., Lake JE; Department of Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Chua JV; Institute of Human Virology, Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Li E; Edetek, Princeton, NJ, USA., Chen J; Edetek, Princeton, NJ, USA., Zhou X; Edetek, Princeton, NJ, USA., He K; R&G US, North Potomac, MD, USA., Gates D; Merck & Co, Kenilworth, NJ, USA., Kaur A; Merck & Co, Kenilworth, NJ, USA., Chen J; Edetek, Princeton, NJ, USA; ClinSmart, Newtown, PA, USA., Chou HY; OncoImmune, Rockville, MD, USA., Devenport M; OncoImmune, Rockville, MD, USA., Touomou R; OncoImmune, Rockville, MD, USA., Kottilil S; Institute of Human Virology, Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Liu Y; OncoImmune, Rockville, MD, USA; Division of Immunotherapy, Institute of Human Virology, UM Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA., Zheng P; OncoImmune, Rockville, MD, USA; Division of Immunotherapy, Institute of Human Virology, UM Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: pzheng@oncoc4.com.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2022 May; Vol. 22 (5), pp. 611-621. Date of Electronic Publication: 2022 Mar 11.