Výsledky vyhledávání - "Tounes Bellahsene"

Design and modeling of new platelet-activating factor antagonists. 3. Relative importance of hydrophobicity and electronic distribution in piperazinic series

Autor: Fabrice Tavet, Estera Touboul, Françoise Heymans, Jean-Jacques Godfroid, Catherine Redeuilh, Georges Dive, Tounes Bellahsene, Aazdine Lamouri, Jack Huet

Publikováno v: Journal of lipid mediators and cell signalling. 15(2)

Extensive analysis of results obtained in earlier publications (Lamouri et al. (1993); Tavet et al. (1996) led us to reexamine our interpretations and conclusions about hydrophobic and electronic distribution effects. In terms of hydrophobicity balan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aea00e0834b4f51799a2d6b939d1751
https://pubmed.ncbi.nlm.nih.gov/9034962

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Structure-activity relationships in platelet-activating factor (PAF). 7. Tetrahydrofuran derivatives as dual PAF antagonists and acetylcholinesterase inhibitors. Synthesis and PAF-antagonistic activity

Autor: Edith Favre, Tounes Bellahsene, Nadine Blavet, Edouardo Pirotzky, Catherine Redeuilh, Georges Dive, Laurence Le Texier, Jean-Jacques Godfroid

Publikováno v: Journal of lipid mediators and cell signalling. 13(3)

2,5-Disubstituted tetrahydrofuran derivatives present a dual activity: they are effective PAF antagonists and acetylcholinesterase inhibitors. In this paper their synthesis and in vitro PAF-antagonistic effect are described. Introduction in position

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed36163150fcdf801f47ddf24548342
https://pubmed.ncbi.nlm.nih.gov/8816984

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