Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Toto Hølmebakk"'
Autor:
Kjetil Boye, Ludmila Gorunova, Bastian Gunawan, Ivar Hompland, Bjoern Sander, Ioannis Panagopoulos, Claus Langer, Monika Golas, Sverre Heim, László Füzesi, Toto Hølmebakk, Francesca Micci
Publikováno v:
JCO Precision Oncology.
PURPOSE Adjuvant imatinib treatment is recommended for patients with localized gastrointestinal stromal tumor (GIST) at high risk of recurrence. Almost half of high-risk patients are cured by surgery alone, indicating a need for improved selection of
Autor:
Anne Marit Wiedswang, Stephan Stoldt, Ingvild Lobmaier, Toto Hølmebakk, Leonardo A. Meza-Zepeda, Jeanne-Marie Berner, Ivar Hompland, Kjetil Boye
Publikováno v:
Annals of Surgical Oncology
Background Adjuvant imatinib for 3 years is recommended to patients with high-risk gastrointestinal stromal tumor (GIST). Risk stratification is inaccurate, and risk assessments are further complicated by the increased use of neoadjuvant treatment. A
Publikováno v:
British Journal of Surgery. 106:419-426
BackgroundAccording to guidelines, adjuvant treatment or re-excision should be considered after R1 resection of gastrointestinal stromal tumours (GISTs). However, the prognostic significance of R1 resection is uncertain and tumour rupture confounds i
Autor:
Thomas Berg, Astrid Stormorken, Ole-Jacob Norum, Eli Marie Grindedal, Sonja E. Steigen, Toto Hølmebakk, Kristin Aaberg
Publikováno v:
Familial Cancer
Source at https://doi.org/10.1007/s10689-018-0072-8. Familial adenomatous polyposis (FAP) is usually caused by germline mutations in the adenomatous polyposis coli (APC) gene. The classic form is characterized by hundreds to thousands of adenomas in
Autor:
K. Sundby Hall, Kjetil Boye, Bodil Bjerkehagen, Ivar Hompland, Stephan Stoldt, Øyvind S. Bruland, Toto Hølmebakk, Jeanne-Marie Berner
Publikováno v:
British Journal of Surgery. 105:e169-e175
Background Tumour rupture is a strong predictor of poor outcome in gastrointestinal stromal tumours (GISTs) of the stomach and small intestine. The objective was to determine whether tumour genotype was associated with risk of rupture. Methods Ruptur
Autor:
Kjetil Boye, Toto Hølmebakk
Publikováno v:
Annals of Surgical Oncology
Ann Surg Oncol
Ann Surg Oncol
Autor:
Sverre Heim, Ioannis Panagopoulos, Toto Hølmebakk, Francesca Micci, Jeanne-Marie Berner, Ivar Hompland, Bodil Bjerkehagen, Ludmila Gorunova, Kjetil Boye
Publikováno v:
Journal of Clinical Oncology. 39:11535-11535
11535 Background: Gastrointestinal stromal tumors (GISTs) are characterized molecularly by oncogenic KIT or platelet-derived growth factor alpha ( PDGFRA) mutations. Malignant progression of primary GISTs occurs through stepwise accumulation of addit
Autor:
Toto Hølmebakk, Bodil Bjerkehagen, Ivar Hompland, Ingvild Lobmaier, Stephan Stoldt, Kjetil Boye
Publikováno v:
Annals of surgical oncology. 26(13)
Peritoneal tumor penetration (PP) strongly affects prognosis in gastrointestinal carcinomas. In gastrointestinal stromal tumor (GIST), its significance in the absence of tumor rupture has not been subjected to detailed analysis. Patients undergoing c
Autor:
Kjetil Boye, Toto Hølmebakk
Publikováno v:
Annals of Surgical Oncology. 28:873-873
Autor:
Bodil Bjerkehagen, K. Sundby Hall, Øyvind S. Bruland, Toto Hølmebakk, Stephan Stoldt, Kjetil Boye
Publikováno v:
British Journal of Surgery. 103:684-691
Background Tumour rupture is a risk factor for recurrence of gastrointestinal stromal tumour (GIST). In this study, patterns of recurrence after potential tumour seeding were investigated, and a new definition of tumour rupture, based on major and mi