Zobrazeno 1 - 10
of 58 507
pro vyhledávání: '"Total synthesis"'
Autor:
Joachim Podlech
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2171-2207 (2024)
In this overview, naturally occurring resorcylic lactones biosynthetically derived from alternariol and almost exclusively produced by fungi, are discussed with view on their isolation, structure, biological activities, biosynthesis, and total synthe
Externí odkaz:
https://doaj.org/article/3646199c0da448d2b761bb968699c280
Akademický článek
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Autor:
Ryo Tanifuji, Hiroki Oguri
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1693-1712 (2024)
A steadily increasing number of reports have been published on chemo-enzymatic synthesis methods that integrate biosynthetic enzymatic transformations with chemical conversions. This review focuses on the total synthesis of natural products and class
Externí odkaz:
https://doaj.org/article/0dac186e54de40f08f80c887f85223b8
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract Cyclobutanes are distributed widely in a large class of natural products featuring diverse pharmaceutical activities and intricate structural frameworks. The [2 + 2] cycloaddition is unequivocally the primary and most commonly used method fo
Externí odkaz:
https://doaj.org/article/67e3c7d1b1fe4a71b29039bdd9c21b30
Autor:
Qing Meng, Jianshuang Guo, Ke Lv, Yang Liu, Jin Zhang, Mingyue Li, Xirui Cheng, Shenghua Chen, Xiaoguang Huo, Quan Zhang, Yue Chen, Jing Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2153-2176 (2024)
Aberrant changes in the gut microbiota are implicated in many diseases, including inflammatory bowel disease (IBD). Gut microbes produce diverse metabolites that can shape the immune system and impact the intestinal barrier integrity, indicating that
Externí odkaz:
https://doaj.org/article/561ce78a4f004b59bb44f08b62103ce1
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 7, Pp 103242- (2024)
After lifting COVID-19 restrictions, pneumonia caused by influenza A virus coinfection with Mycoplasma pneumoniae bacteria emerges as a matter of concern. Only a few reports have recently proposed natural compounds for treating the coinfection of inf
Externí odkaz:
https://doaj.org/article/da286504b8744159827eb0c521d5a25f
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 220-227 (2024)
Lipid II is an essential glycolipid found in bacteria. Accessing this valuable cell wall precursor is important both for studying cell wall synthesis and for studying/identifying novel antimicrobial compounds. Herein, we describe optimizations to the
Externí odkaz:
https://doaj.org/article/c1986121f19943f99d556cd95b504c5f
Autor:
Prof. Enrique L. Larghi, Dr. Andrea B. J. Bracca, Dr. Sebastian O. Simonetti, Prof. Teodoro S. Kaufman
Publikováno v:
ChemistryOpen, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Multicomponent reactions (MCRs) offer a highly useful and valuable strategy that can fulfill an important role in synthesizing complex polysubstituted compounds, by simplifying otherwise long sequences and increasing their efficiency. The to
Externí odkaz:
https://doaj.org/article/a887308c1e1b47b0bc204e1a1cf390a3
Publikováno v:
Molecules, Vol 29, Iss 17, p 4058 (2024)
A novel and concise synthetic method for arenastatin A, a cytotoxic cyclic depsipeptide of marine origin, was developed in this study. The convergent assembly of the four segments, including the cross-metathesis reaction, gave a cyclization precursor
Externí odkaz:
https://doaj.org/article/bfa2bdacf0044f8987207c4e830c3e72
Publikováno v:
Molecules, Vol 29, Iss 16, p 3942 (2024)
Licorice (Glycyrrhiza uralensis Fisch), a significant traditional Chinese herbal medicine, has been extensively utilized in China to treat various ailments. Natural bioactive coumarins, glycycoumarin, glycyrin, and 3-O-methylglycyrol, were isolated f
Externí odkaz:
https://doaj.org/article/13c65752946c465b8ca87c4b2ee3e6f3