Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Total neoadjuvant therapy"'
Autor:
Luís Correia Gomes, Bernardo Alves Pereira, Isália Miguel, Ana Luís, Ana Pina, Cátia Pedro, Daniela Cavadas, Daniela Pereira, Joana Lemos, João Maciel, João Oliveira, José Venâncio, Madalena Santos, Manuel Limbert, Miguel Braga, Miriam Abdulrehman, Pedro Freitas, Ricardo Fonseca, Teresa Ferreira, Isadora Rosa
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Locally advanced rectal cancer (LARC) poses a significantly challenge in clinical management, requiring a multimodal treatment approach. Among innovative strategies, Total Neoadjuvant Therapy (TNT) has emerged, delivering all plan
Externí odkaz:
https://doaj.org/article/ddf8bc71bfa64ab58f2bc7f8e934cd35
Autor:
Yoshinori Kagawa, Koji Ando, Mamoru Uemura, Jun Watanabe, Koji Oba, Yasunori Emi, Nobuhisa Matsuhashi, Naoki Izawa, Osamu Muto, Tatsuya Kinjo, Ichiro Takemasa, Eiji Oki
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1067-1075 (2024)
Abstract Aim To evaluate the feasibility and safety of total neoadjuvant therapy with long‐course chemoradiotherapy followed by consolidation chemotherapy in Japanese patients with locally advanced rectal cancer. Methods This prospective, multicent
Externí odkaz:
https://doaj.org/article/3d67fb3ae60f4273881d57e185a2000d
Autor:
Gyu-Seog Choi, Hye Jin Kim
Publikováno v:
Annals of Coloproctology, Vol 40, Iss 4, Pp 363-374 (2024)
Metastatic lateral pelvic lymph nodes (LPNs) in rectal cancer significantly impact the prognosis and treatment strategies. Western practices emphasize neoadjuvant chemoradiotherapy (CRT), whereas Eastern approaches often rely on LPN dissection (LPND)
Externí odkaz:
https://doaj.org/article/ca25a0497aa34bfdbbba3ffe2a8abf62
Autor:
Erik Manriquez, Sebastián Solé, Javiera Silva, Juan Pablo Hermosilla, Rubén Romero, Felipe Quezada-Diaz
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4292-4304 (2024)
Rectal cancer management has evolved significantly, particularly with neoadjuvant treatment strategies. This narrative review examines the development and effectiveness of these therapies for locally advanced rectal cancer (LARC), highlighting the hi
Externí odkaz:
https://doaj.org/article/0d43b677a035436aa1a7a4b1a47993d7
Autor:
Janet A. Alvarez, Qian Shi, Arvind Dasari, Julio Garcia-Aguilar, Hanna Sanoff, Thomas J. George, Theodore Hong, Greg Yothers, Philip Philip, Garth Nelson, Tareq Al Baghdadi, Olatunji B. Alese, Wini Zambare, Dana Omer, Floris S. Verheij, Aron Bercz, Min Jung Kim, James Buckley, Hannah Williams, Manju George, Reese Garcia, Phuong Gallagher, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Jamie Crawley, Ardaman Shergill, Natally Horvat, Paul B. Romesser, William Hall, J. Joshua Smith
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Recent data have demonstrated that in locally advanced rectal cancer (LARC), a total neoadjuvant therapy (TNT) approach improves compliance with chemotherapy and increases rates of tumor response compared to neoadjuvant chemoradia
Externí odkaz:
https://doaj.org/article/f410276cdec24b44bc5dee5b6d527eee
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The management of locally advanced rectal cancer has changed drastically in the last few decades due to improved surgical techniques, development of multimodal treatment approaches and the introduction of a watch and wait (WW) strategy. For patients
Externí odkaz:
https://doaj.org/article/e61203dad446437c967ee572b254f6a8
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThe management of rectal adenocarcinoma has evolved during the last decade, shifting from a conventional neoadjuvant chemoradiotherapy, surgery, and adjuvant chemotherapy in all cases to a total neoadjuvant approach, especially in locally adva
Externí odkaz:
https://doaj.org/article/ecbbc435733c4c2fa1833138ddbc434b
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immuno-oncological cancer management is shifting to neoadjuvant treatments. In patients with gastrointestinal cancers, particularly locally advanced rectal cancer, neoadjuvant chemoimmunotherapy often induce complete responses, hence avoiding surgica
Externí odkaz:
https://doaj.org/article/18ec85d9401b497a93c1b96895318086
Autor:
Linlin Xiao, Shiyu Zhuo, Yuanhang Gao, Jingyi Sun, Yuting Xiao, Lu Wang, Xuan Wang, Fuyin Qu, Ming Liu, Yi Wang, Chao Gao, Jun Wang, Fengpeng Wu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis study aims to optimize neoadjuvant radiotherapy target area for locally advanced rectal cancer (LARC) patients undergoing total neoadjuvant therapy (TNT) by examining local recurrence patterns.Methods and materialsWe retrospectively analy
Externí odkaz:
https://doaj.org/article/eb5c24ac30c647f38f6794835065e735
Autor:
Reza Ghalehtaki, Forouzan Nourbakhsh, Romina Abyaneh, Azadeh Sharifian, Sheyda Pashapour‐Khoyi, Mahdi Aghili, Maria Antonietta Gambacorta, Felipe Couñago
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Introduction Historically, multimodal therapeutic strategies involving preoperative chemoradiotherapy (CRT), surgery, and adjuvant chemotherapy (CT) have been employed to treat locally advanced rectal cancer (LARC). Total Neoadjuvant Therapy
Externí odkaz:
https://doaj.org/article/9d5137e0825b4de58481a49f220f967a