Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Total drug clearance"'
Autor:
Koichi Handa, Takahisa Motomura, Takeshi Fujiwara, Tatsuru Matsuo, Hiroaki Iwata, Maeda Kazuya, Hideaki Mamada, Mayumi Matsushita
Publikováno v:
Journal of pharmaceutical sciences. 110(4)
Research into pharmacokinetics plays an important role in the development process of new drugs. Accurately predicting human pharmacokinetic parameters from preclinical data can increase the success rate of clinical trials. Since clearance (CL) which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d955f249c12184b35b1cbba1eb2281e
https://pubmed.ncbi.nlm.nih.gov/33497658
https://pubmed.ncbi.nlm.nih.gov/33497658
Autor:
Steffen Simon, Thomas Frankewitsch, Michael Giehl, Frieder Keller, David Czock, Dietmar Zellner
Publikováno v:
Computer Methods and Programs in Biomedicine. 55:107-115
Background: the accumulated knowledge on drugs can be used for an individual drug dosage adjustment if it is placed at our disposal in an informatically structured form. Theory and methods: we have started building up a pharmacokinetic database aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abb1b0d3111747d924e6d00281f3ede
https://doi.org/10.1016/s0169-2607(97)00061-8
https://doi.org/10.1016/s0169-2607(97)00061-8
Akademický článek
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Publikováno v:
Klinische Wochenschrift. 66(6)
The pharmacokinetics of a slow-release formulation of bezafibrate were investigated under steady-state conditions in 19 hyperlipidemic patients between the age of 61 and 87 years and compared to the kinetics in 20 healthy volunteers (age 19–42 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2256a692847ce2567e668757c88a0759
https://pubmed.ncbi.nlm.nih.gov/3367617
https://pubmed.ncbi.nlm.nih.gov/3367617