Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Autor: O’Brien, Heath E., Hannon, Eilis, Hill, Matthew J., Toste, Carolina C., Robertson, Matthew J., Morgan, Joanne E., McLaughlin, Gemma, Lewis, Cathryn M., Schalkwyk, Leonard C., Hall, Lynsey S., Pardiñas, Antonio F., Owen, Michael J., O’Donovan, Michael C., Mill, Jonathan, Bray, Nicholas J.

Publikováno v: Genome Biology
Genome Biology, Vol 19, Iss 1, Pp 1-13 (2018)
O'Brien, H E, Hannon, E, Hill, M J, Toste, C C, Robertson, M J, Morgan, J E, McLaughlin, G, Lewis, C M, Schalkwyk, L C, Hall, L S, Pardiñas, A F, Owen, M J, O'Donovan, M C, Mill, J & Bray, N J 2018, ' Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders ', Genome Biology, vol. 19, no. 1, pp. 194 . https://doi.org/10.1186/s13059-018-1567-1

Background Genetic influences on gene expression in the human fetal brain plausibly impact upon a variety of postnatal brain-related traits, including susceptibility to neuropsychiatric disorders. However, to date, there have been no studies that hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::26ef4fa34fa53a406b935aa6935cd47e
http://europepmc.org/articles/PMC6231252

No Effect of Genome-Wide Significant Schizophrenia Risk Variation at the DRD2 Locus on the Allelic Expression of DRD2 in Postmortem Striatum.

Autor: Toste, Carolina C., Duarte, Rodrigo R.R., Jeffries, Aaron R., Selvackadunco, Sashika, Troakes, Claire, O'Donovan, Michael C., Hill, Matthew J., Bray, Nicholas J.

Publikováno v: Molecular Neuropsychiatry; Jul2019, Vol. 5 Issue 4, p212-217, 6p