Zobrazeno 1 - 10
of 2 166
pro vyhledávání: '"Tosso"'
Autor:
Keijiro Mizukami, Angella Dorsey-Oresto, Karthik Raj, Anna Eringis, Eva Furrow, Errolyn Martin, Daisuke Yamanaka, Alexandra Kehl, Ana Kolicheski, Vidhya Jagannathan, Tosso Leeb, Michail S. Lionakis, Urs Giger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Mammals are generally resistant to Mycobacterium avium complex (MAC) infections. We report here on a primary immunodeficiency disorder causing increased susceptibility to MAC infections in a canine breed. Adult Miniature Schnauzers developin
Externí odkaz:
https://doaj.org/article/a177f7a1f6b44f2e9545cce2574d3ba7
Autor:
Matthias Christen, Anne Gregor, Rodrigo Gutierrez-Quintana, Jos Bongers, Angie Rupp, Jacques Penderis, G. Diane Shelton, Vidhya Jagannathan, Christiane Zweier, Tosso Leeb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Two Jack-Russell Terrier × Chihuahua mixed-breed littermates with Leigh syndrome were investigated. The dogs presented with progressive ataxia, dystonia, and increased lactate levels. Brain MRI showed characteristic bilateral symmetrical T2
Externí odkaz:
https://doaj.org/article/f2308b3ba95b4cfeba689d785e3d4ca7
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 1, Pp 277-284 (2024)
Abstract Background Polioencephalopathies secondary to inborn errors of metabolism have been described in dogs, but few genetically characterized. Objectives Clinically and genetically characterize polioencephalopathy in a family of Eurasier dogs. An
Externí odkaz:
https://doaj.org/article/802ebb63618c4655b91b9392a872e827
Autor:
Danika L. Bannasch, Danielle T. Oertle, Julia Vo, Kevin L. Batcher, Joshua A. Stern, Joanna L. Kaplan, Ronald H. L. Li, Indiana E. Madden, Matthias Christen, Tosso Leeb, Nikhil Joshi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Dilated cardiomyopathy (DCM) is characterized by decreased systolic function and dilation of one or both ventricles, often leading to heart failure or sudden death. Two 10-month-old sibling Nova Scotia Duck Tolling Retrievers (NSDTR) died ac
Externí odkaz:
https://doaj.org/article/ef7067c58fce4a5db32de339fd96ab57
Autor:
Julia E. Niskanen, Åsa Ohlsson, Ingrid Ljungvall, Michaela Drögemüller, Robert F. Ernst, Dennis Dooijes, Hanneke W. M. van Deutekom, J. Peter van Tintelen, Christian J. B. Snijders Blok, Marion van Vugt, Jessica van Setten, Folkert W. Asselbergs, Aleksandra Domanjko Petrič, Milla Salonen, Sruthi Hundi, Matthias Hörtenhuber, DoGA consortium, Juha Kere, W. Glen Pyle, Jonas Donner, Alex V. Postma, Tosso Leeb, Göran Andersson, Marjo K. Hytönen, Jens Häggström, Maria Wiberg, Jana Friederich, Jenny Eberhard, Magdalena Harakalova, Frank G. van Steenbeek, Gerhard Wess, Hannes Lohi
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background Dilated cardiomyopathy (DCM) is a life-threatening heart disease and a common cause of heart failure due to systolic dysfunction and subsequent left or biventricular dilatation. A significant number of cases have a genetic etiolog
Externí odkaz:
https://doaj.org/article/49a1dbcf15a6421cbf422ecc2a464ea9
Autor:
Jennifer R. S. Meadows, Jeffrey M. Kidd, Guo-Dong Wang, Heidi G. Parker, Peter Z. Schall, Matteo Bianchi, Matthew J. Christmas, Katia Bougiouri, Reuben M. Buckley, Christophe Hitte, Anthony K. Nguyen, Chao Wang, Vidhya Jagannathan, Julia E. Niskanen, Laurent A. F. Frantz, Meharji Arumilli, Sruthi Hundi, Kerstin Lindblad-Toh, Catarina Ginja, Kadek Karang Agustina, Catherine André, Adam R. Boyko, Brian W. Davis, Michaela Drögemüller, Xin-Yao Feng, Konstantinos Gkagkavouzis, Giorgos Iliopoulos, Alexander C. Harris, Marjo K. Hytönen, Daniela C. Kalthoff, Yan-Hu Liu, Petros Lymberakis, Nikolaos Poulakakis, Ana Elisabete Pires, Fernando Racimo, Fabian Ramos-Almodovar, Peter Savolainen, Semina Venetsani, Imke Tammen, Alexandros Triantafyllidis, Bridgett vonHoldt, Robert K. Wayne, Greger Larson, Frank W. Nicholas, Hannes Lohi, Tosso Leeb, Ya-Ping Zhang, Elaine A. Ostrander
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-41 (2023)
Abstract Background The international Dog10K project aims to sequence and analyze several thousand canine genomes. Incorporating 20 × data from 1987 individuals, including 1611 dogs (321 breeds), 309 village dogs, 63 wolves, and four coyotes, we ide
Externí odkaz:
https://doaj.org/article/070c928591184511adb6d4a61799d1db
Autor:
Jennifer R. S. Meadows, Jefrey M. Kidd, Guo-Dong Wang, Heidi G. Parker, Peter Z. Schall, Matteo Bianchi, Matthew J. Christmas, Katia Bougiouri, Reuben M. Buckley, Christophe Hitte, Anthony K. Nguyen, Chao Wang, Vidhya Jagannathan, Julia E. Niskanen, Laurent A. F. Frantz, Meharji Arumilli, Sruthi Hundi, Kerstin Lindblad-Toh, Catarina Ginja, Kadek Karang Agustina, Catherine André, Adam R. Boyko, Brian W. Davis, Michaela Drögemüller, Xin-Yao Feng, Konstantinos Gkagkavouzis, Giorgos Iliopoulos, Alexander C. Harris, Marjo K. Hytönen, Daniela C. Kalthof, Yan-Hu Liu, Petros Lymberakis, Nikolaos Poulakakis, Ana Elisabete Pires, Fernando Racimo, Fabian Ramos-Almodovar, Peter Savolainen, Semina Venetsani, Imke Tammen, Alexandros Triantafyllidis, Bridgett vonHoldt, Robert K. Wayne, Greger Larson, Frank W. Nicholas, Hannes Lohi, Tosso Leeb, Ya-Ping Zhang, Elaine A. Ostrander
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/9d22509f6da04b749ce4f0889d709eea
Autor:
Matthias Christen, Veronica Gonzalo‐Nadal, Adriana Kaczmarska, Magdalena Dyrka, Julien Guevar, Vidhya Jagannathan, Tosso Leeb, Rodrigo Gutierrez‐Quintana
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 2, Pp 676-680 (2023)
Abstract Case Description A 9‐month‐old intact male domestic shorthair cat was evaluated for increasing frequency of generalized tonic‐clonic seizures. Clinical Findings The cat was reported to have had episodes of circling between the seizures
Externí odkaz:
https://doaj.org/article/23f793f3744d442fada9679a4a5bccac
Autor:
Rodrigo Gutierrez‐Quintana, Matthias Christen, Kiterie M. E. Faller, Julien Guevar, Vidhya Jagannathan, Tosso Leeb
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 230-235 (2023)
Abstract Background Congenital insensitivity to pain (CIP) and hereditary sensory and autonomic neuropathies (HSANs) are a rare group of genetic disorders causing inability to feel pain. Three different associated variants have been identified in dog
Externí odkaz:
https://doaj.org/article/8fcbc6b3b8ac49f4b022cb78c957f377
Autor:
Katarina Tengvall, Elisabeth Sundström, Chao Wang, Kerstin Bergvall, Ola Wallerman, Eric Pederson, Åsa Karlsson, Naomi D. Harvey, Sarah C. Blott, Natasha Olby, Thierry Olivry, Gustaf Brander, Jennifer R. S. Meadows, Petra Roosje, Tosso Leeb, Åke Hedhammar, Göran Andersson, Kerstin Lindblad-Toh
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
A genome-wide evaluation in four different dog breeds identifies multiple genomic regions that were significantly related to risk of atopic dermatitis, providing additional biological insights into disease pathogenesis in dogs.
Externí odkaz:
https://doaj.org/article/2c6d21673f5142eea8b62a2f6eb0b142