Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Toshiyuki Takehara"'
Autor:
Kensuke Toriumi, Yuta Onodera, Toshiyuki Takehara, Tatsufumi Mori, Joe Hasei, Kanae Shigi, Natsumi Iwawaki, Toshifumi Ozaki, Masao Akagi, Mahito Nakanishi, Takeshi Teramura
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106946- (2023)
Summary: Mesenchymal stem cells (MSCs) are used as a major source for cell therapy, and its application is expanding in various diseases. On the other hand, reliable method to evaluate quality and therapeutic properties of MSC is limited. In this stu
Externí odkaz:
https://doaj.org/article/af0091356a444936a1dae3d65fd52613
Autor:
Yuta Onodera, Takeshi Teramura, Toshiyuki Takehara, Maki Itokazu, Tatsufumi Mori, Kanji Fukuda
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204860 (2018)
Tissue renewal and muscle regeneration largely rely on the proliferation and differentiation of muscle stem cells called muscular satellite cells (MuSCs). MuSCs are normally quiescent, but they are activated in response to various stimuli, such as in
Externí odkaz:
https://doaj.org/article/b3ca824476254fe6b764acd5e556312a
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 492-501 (2015)
Oxidative stress within the arthritis joint has been indicated to be involved in generating mediators for tissue degeneration and inflammation. COX‐2 is a mediator in inflammatory action, pain and some catabolic reactions in inflamed tissues. Here,
Externí odkaz:
https://doaj.org/article/30849c63087f4e53b94bc872c704381b
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 476-484 (2015)
One important pharmacological function of hyaluronic acid (HA) in chondrocytes is reduction of cellular superoxide generation and accumulation. Here we demonstrated a relationship between HA supplementation and accumulation of Nuclear factor‐erythr
Externí odkaz:
https://doaj.org/article/6481c50207494948b790650f2534062e
Autor:
Takeshi Teramura, Yuta Onodera, Toshiyuki Takehara, John Frampton, Toshiki Matsuoka, Syunsuke Ito, Koichi Nakagawa, Yoshihisa Miki, Yoshihiko Hosoi, Chiaki Hamanishi, Kanji Fukuda
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Embryonic stem cells (ESCs) have the potential to be used as an unlimited cell source for cell transplantation therapy, as well as for studying mechanisms of disease and early mammalian development. However, applications involving ESCs have been limi
Externí odkaz:
https://doaj.org/article/bff2f8b73a084e8cbc30497082db09e8
Autor:
Tatsufumi Mori, Masatsugu Igarashi, Yuta Onodera, Toshiyuki Takehara, Maki Itokazu, Takeshi Teramura
Publikováno v:
Biochemical and Biophysical Research Communications. 651:70-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd158de7b509fe88b032fc8be987004
https://doi.org/10.1016/j.bbrc.2023.02.009
https://doi.org/10.1016/j.bbrc.2023.02.009
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Kazuko Sakai, Hidetoshi Hayashi, Hisato Kawakami, Junko Tanizaki, Koji Haratani, Hitomi Sakai, Ryoji Kato, Toshiyuki Takehara, Takeshi Teramura, Kimio Yonesaka, Shinichiro Suzuki
Purpose:Treatment with KRASG12C inhibitors such as sotorasib can produce substantial regression of tumors in some patients with non–small cell lung cancer (NSCLC). These patients require alternative treatment after acquiring resistance to the inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515508c588c2e1caeb4109c863e2de8b
https://doi.org/10.1158/1078-0432.c.6530453.v1
https://doi.org/10.1158/1078-0432.c.6530453.v1
Autor:
Toshiyuki Takehara, Kimio Yonesaka, Hitomi Sakai, Koji Haratani, Hidetoshi Hayashi, Kazuko Sakai, Hisato Kawakami, Kazuhiko Nakagawa, Takeshi Teramura, Shinichiro Suzuki, Kazuto Nishio, Ryoji Kato, Junko Tanizaki
Publikováno v:
Clinical Cancer Research. 27:5697-5707
Purpose: Treatment with KRASG12C inhibitors such as sotorasib can produce substantial regression of tumors in some patients with non–small cell lung cancer (NSCLC). These patients require alternative treatment after acquiring resistance to the inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9388875a02674208e3868a97c2eb6a7d
https://doi.org/10.1158/1078-0432.ccr-21-0856
https://doi.org/10.1158/1078-0432.ccr-21-0856
Autor:
Kanae Shigi, Kanji Fukuda, Toshiyuki Takehara, Shinichi Nakao, Yuta Onodera, Takatoshi Tsujimoto, Takeshi Teramura, Kei Houri, Tatsufumi Mori
Publikováno v:
Biochemical and Biophysical Research Communications. 523:707-712
Removal of dysfunctional mitochondria is essential step to maintain normal cell physiology, and selective autophagy in mitochondria, called mitophagy, plays a critical role in quality control of mitochondria. While in several diseases and aging, dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e26b43f7c06df542bf6212b1a3aa5b
https://doi.org/10.1016/j.bbrc.2020.01.022
https://doi.org/10.1016/j.bbrc.2020.01.022
Autor:
Shinichiro, Suzuki, Kimio, Yonesaka, Takeshi, Teramura, Toshiyuki, Takehara, Ryoji, Kato, Hitomi, Sakai, Koji, Haratani, Junko, Tanizaki, Hisato, Kawakami, Hidetoshi, Hayashi, Kazuko, Sakai, Kazuto, Nishio, Kazuhiko, Nakagawa
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b1c2ee21ed39a0bb3ad179d58002a73
https://pubmed.ncbi.nlm.nih.gov/34365406
https://pubmed.ncbi.nlm.nih.gov/34365406