Výsledky vyhledávání - "Toshiyuki TAMAGAKI"

Bradykinin Inhibits Serum-Depletion-Induced Apoptosis of Human Vascular Endothelial Cells by Inducing Nitric Oxide via Calcium Ion Kinetics

Autor: Hitoshi Imamura, Tadashi Higaki, Masao Nakagawa, Naoaki Akamatsu, Shohei Sawada, Yutaka Tsuda, Katsumi Nakagawa, Seiki Yamasaki, Takeshi Kawahara, Yusuke Tada, Yoshihito Kono, Toshiyuki Tamagaki, Sumio Komatsu, Toshiyuki Sato, Hajime Tsuji, Osamu Hiranuma

Publikováno v: Journal of Cardiovascular Pharmacology. 39:251-261

Vascular endothelial cells play important roles in atherogenesis, and bradykinin is associated with atherosclerosis. The effect of bradykinin on apoptosis in human umbilical vein endothelial cells (HUVECs) was investigated, with a focus on Ca2+ kinet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11248efa8dad2dbaea531fd86822270
https://doi.org/10.1097/00005344-200202000-00012

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Effects of Bradykinin on Prostaglandin I 2 Synthesis in Human Vascular Endothelial Cells

Autor: Takeshi Kawahara, Sumio Komatsu, Toshiyuki Tamagaki, Masao Nakagawa, Hajime Tsuji, Shohei Sawada, Yusuke Tada, Akihisa Toratani, Yoshihito Kono, Tadashi Higaki, Hitoshi Imamura, Naoaki Akamatsu, Toshiyuki Sato, Yutaka Tsuda, Seiki Yamasaki

Publikováno v: Hypertension. 36:201-207

Abstract —The effects of bradykinin on the regulatory mechanisms of prostacyclin synthesis in endothelial cells were investigated in association with intracellular Ca 2+ kinetics, cytosolic phospholipase A 2 (cPLA 2 ) activity, and mRNA expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15d7e5211fe4aad65dc206b3cac24bf
https://doi.org/10.1161/01.hyp.36.2.201

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A Role of Protein Kinase C in the Regulation of Cytosolic Phospholipase A2 in Bradykinin-Induced PGI2 Synthesis by Human Vascular Endothelial Cells

Autor: Yutaka Tsuda, Yusuke Tada, Masao Nakagawa, Tadashi Higaki, Seiki Yamasaki, Toshiyuki Sato, Toshiyuki Tamagaki, Shohei Sawada, Hajime Tsuji, Akihisa Toratani, Yoshihito Kono, Naoaki Akamatsu, Hitoshi Imamura, Sumio Komatsu

Publikováno v: Microvascular Research. 58:144-155

The purpose of this study was to elucidate the mechanism by which bradykinin (BK) enhances prostacyclin (PGI 2 ) production in human umbilical vein endothelial cells (HUVEC). BK-induced enhancement of PGI 2 synthesis was observed in a dose- and time-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed17fb1cec5bd6fb491c36d18b6460e
https://doi.org/10.1006/mvre.1999.2163

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The mechanism of thrombin-induced prostacyclin synthesis in human endothelial cells with reference to the gene transcription of prostacyclin-related enzymes and Ca2+ kinetics

Autor: Yusuke Tada, Yutaka Tsuda, Seiki Yamasaki, Katsumi Nakagawa, Hitoshi Imamura, Hajime Tsuji, Yoshihito Kono, Tadashi Higaki, Shohei Sawada, Naoaki Akamatsu, Toshiyuki Tamagaki, Toshiyuki Sato, Masao Nakagawa, Sumio Komatsu

Publikováno v: Journal of Pharmacological and Toxicological Methods. 41:173-182

This study was designed to evaluate the effect of thrombin on prostacyclin (PGI2) production in cultured human vascular endothelial cells in association with intracellular Ca2+ and with the gene expression of prostaglandin H2 synthase (PGHS) and phos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1c3a484eb1d811f231923a0eefa074
https://doi.org/10.1016/s1056-8719(99)00039-8

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Interleukin-1α Stimulated Prostacyclin Release by Increasing Gene Transcription of Prostaglandin H Synthase and Phospholipase A2 in Human Vascular Endothelial Cells

Autor: Masao Nakagawa, Sumio Komatsu, Shohei Sawada, Hitoshi Imamura, Hajime Tsuji, Seiki Yamasaki, Akihisa Toratani, Toshiyuki Tamagaki, Toshiyuki Sato, Naoaki Akamatsu, Tadashi Higaki, Yoshihito Kono, Katsumi Nakagawa, Yusuke Tada

Publikováno v: Journal of Cardiovascular Pharmacology. 33:843-851

This study was conducted to evaluate the effects of interleukin-1alpha (IL-1alpha) on prostacyclin (PGI2) production in cultured human vascular endothelial cells in association with intracellular Ca2+, inositol 1,4,5-trisphosphate (IP3), and with pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbc3814d8a22ec64370d90a3140d932
https://doi.org/10.1097/00005344-199906000-00003

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Malignant pleural effusions due to adeno-endocrine-cell carcinoma of the appendix: A case report

Autor: Shinsuke Watanabe M.D., Ryoji Kushima M.D., C T Toshihiro Nishino, C T Masami Ueda, Toshiyuki Tamagaki, C.F.I.A.C. Tadao K. Kobayashi Ph.D.

Publikováno v: Diagnostic Cytopathology. 16:522-525

The cellular features of adeno-endocrine-cell carcinoma of appendiceal origin are presented. The pleural fluid contained metastatic predominantly atypical cells in linear cluster accompanied by numerous mesothelial cells. The cells had small round nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ba841c685af5bb3744c80cb8caeef48
https://doi.org/10.1002/(sici)1097-0339(199706)16:6<522::aid-dc10>3.0.co

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The Mechanism of Thrombin Induced Prostaglandin I2 (PGI2) Enhancement in Human Umbilical Vein Endothelial Cells with Reference to the Gene Expression of PGI2 Related Enzymes and Calcium Ion Kinetics

Autor: Kazuharu Kato, Seiki Yamazaki, Hajime Tsuji, Toshiyuki Sato, Akihisa Toratani, Sumio Komatsu, Yusuke Tada, Naoaki Akamatsu, Masao Nakagawa, Toshiyuki Tamagaki, Hitoshi Imamura, Shohei Sawada, Tadashi Higaki, Masahito Yamagami, Katsumi Nakagawa

Publikováno v: Japanese Journal of Thrombosis and Hemostasis. 8:112-121

Signal induction and molecular mechanisms of the thrombin induced prostaglandin I2 (PGI2) synthesis in human umbilical vein endothelial cells (HUVEC) were investigated in association with the intra Ca2+ and the gene expression of prostaglandin H2 syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1eff5156cd422f42b1c088cd55e5731
https://doi.org/10.2491/jjsth.8.112

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Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells

Autor: Hajime Tsuji, Katsumi Nakagawa, Akihisa Toratani, Shohei Sawada, Toshiyuki Sato, Hitoshi Imamura, Sumio Komatsu, Masao Nakagawa, Kazuharu Kato, Katsumi Yamamoto, Toshiyuki Tamagaki, Tadashi Higaki, Seiki Yamasaki, Naoaki Akamatsu, Kaoru Shirai, Kyoichiro Kobayashi, Keizo Yamada, Mashahito Yamagami, Y. Tada

Publikováno v: Atherosclerosis. 123:73-82

We investigated the effects of high-density lipoprotein (HDL) on the intracellular pH ([pH] i ), and on the proliferation of human vascular endothelial cells (HUVEC), as well as on their production of prostacyclin (PGI 2 ). The [pH] i was slightly ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d9404f0193d9100e98d4b3b57c1eb1
https://doi.org/10.1016/0021-9150(95)05774-9

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