Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Toshiyuki Owaki"'
Autor:
Yoshiyuki Kasai, Ryo Takagi, Shinichiro Kobayashi, Toshiyuki Owaki, Naoyuki Yamaguchi, Hiroko Fukuda, Yusuke Sakai, Yoshinori Sumita, Nobuo Kanai, Hajime Isomoto, Kengo Kanetaka, Takeshi Ohki, Izumi Asahina, Kazuhiro Nagai, Kazuhiko Nakao, Naoya Takeda, Teruo Okano, Susumu Eguchi, Masayuki Yamato
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 87-94 (2020)
Introduction: Cultured stratified epithelial cell sheets have been clinically utilized as transplantable grafts for the regeneration of epithelial tissues, such as the esophagus, cornea, skin, and intraoral cavity. These cell sheets are expected to g
Externí odkaz:
https://doaj.org/article/72f6a459f6624a6dad23539c231293c6
Autor:
Naoko Orii, Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Taro Nagai, Nakaba Ochiai, Yuki Mochizuki, Toshiyuki Owaki, Takayuki Yoshimoto
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Interleukin (IL)-27 is a multifunctional cytokine that belongs to the IL-6/IL-12 family and has potent antitumor activity through various mechanisms. Our novel findings indicate that IL-27 directly acts on hematopoietic stem cells and promotes their
Externí odkaz:
https://doaj.org/article/a964effe11f54bc38921a60a6811dbcc
Autor:
Ryo Takagi, Shinichiro Kobayashi, Masayuki Yamato, Toshiyuki Owaki, Yoshiyuki Kasai, Takahiro Hosoi, Yusuke Sakai, Kengo Kanetaka, Tokutaro Minamizato, Asuka Minematsu, Makoto Kondo, Nobuo Kanai, Naoyuki Yamaguchi, Kazuhiro Nagai, Yasushi Miyazaki, Naoya Takeda, Fumio Fukai, Izumi Asahina, Taiga Miyazaki, Shigeru Kohno, Masakazu Yamamoto, Kazuhiko Nakao, Susumu Eguchi, Teruo Okano
Publikováno v:
Regenerative Therapy, Vol 1, Iss C, Pp 1-4 (2015)
We have utilized patients' own oral mucosa as a cell source for the fabrication of transplantable epithelial cell sheets to treat limbal stem cell deficiency and mucosal defects after endoscopic submucosal dissection of esophageal cancer. Because the
Externí odkaz:
https://doaj.org/article/03c6cc028cbe4af0acbe5b567ce75cdd
Autor:
Izuru Mizoguchi, Mio Ohashi, Yukino Chiba, Hideaki Hasegawa, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The use of animal models in chemical safety testing will be significantly limited due to the recent introduction of the 3Rs principle of animal experimentation in research. Although several in vitro assays to predict the sensitizing potential of chem
Externí odkaz:
https://doaj.org/article/ec289bf1b1cf451b9ba61549a1a2c0f9
Autor:
Takuya Iyoda, Yumi Nagamine, Yoshitomi Nakane, Yuya Tokita, Shougo Akari, Kazuki Otsuka, Motomichi Fujita, Keisuke Itagaki, You-Ichi Takizawa, Hiroaki Orita, Toshiyuki Owaki, Jyunichi Taira, Ryo Hayashi, Hiroaki Kodama, Fumio Fukai
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162525 (2016)
The acquisition of drug resistance mediated by the interaction of tumor cells with the extracellular matrix (ECM), commonly referred to as cell adhesion-mediated drug resistance (CAM-DR), has been observed not only in hematopoietic tumor cells but al
Externí odkaz:
https://doaj.org/article/7ca555ab31244a85abea6be1068b9b8c
Autor:
Yuma Furusaka, Shinya Inoue, Izuru Mizoguchi, Hideaki Hasegawa, Yasuhiro Katahira, Aruma Watanabe, Eri Sakamoto, Ami Sekine, Satomi Miyakawa, Tomohiro Umezu, Toshiyuki Owaki, Toshihiko Yoneto, Takayuki Yoshimoto
Publikováno v:
Cancer Science.
Autor:
Takayuki Yoshimoto, Toshiyuki Owaki, Mingli Xu, Mio Ohashi, Hideaki Hasegawa, Junichi Furusawa, Izuru Mizoguchi, Yukino Chiba
The interleukin IL27 promotes expansion and differentiation of hematopoietic stem cells into myeloid progenitor cells. Many tumor-infiltrating myeloid cells exert immunosuppressive effects, but we hypothesized that the myeloid cells induced by IL27 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9579f5726e47c6a8e8b53d431750b9d
https://doi.org/10.1158/0008-5472.c.6509889.v1
https://doi.org/10.1158/0008-5472.c.6509889.v1
Autor:
Takayuki Yoshimoto, Toshiyuki Owaki, Mingli Xu, Mio Ohashi, Hideaki Hasegawa, Junichi Furusawa, Izuru Mizoguchi, Yukino Chiba
This file contains Supplemental Table 1, Supplementary Figure Legends, and Supplementary Figures. Supplemental Table 1 shows primers used in this study. Supplementary Figure Legends describe the legend for each supplementary figure. Figure S1 shows t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2624f616d4b11b2fc228999078aadb8d
https://doi.org/10.1158/0008-5472.22417611
https://doi.org/10.1158/0008-5472.22417611
Autor:
Toshiyuki Owaki, Daisuke Sugiyama
Publikováno v:
Translational and Regulatory Sciences. 1:37-39
Autor:
Mio Ohashi, Toshiyuki Owaki, Hideaki Hasegawa, Takayuki Yoshimoto, Yukino Chiba, Taro Nagai, Naoko Orii, Izuru Mizoguchi, Mingli Xu, Yasunori Miyamoto, Miyaka Sugahara
Publikováno v:
Cellular and Molecular Life Sciences. 75:1363-1376
Hematopoiesis is hierarchically orchestrated by a very small population of hematopoietic stem cells (HSCs) that reside in the bone-marrow niche and are tightly regulated to maintain homeostatic blood production. HSCs are predominantly quiescent, but