Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Toshiyuki Nakagawa"'
Autor:
Yuichi Hayashi, Fuminori Hyodo, Tana, Kiyomi Nakagawa, Takuma Ishihara, Masayuki Matsuo, Takayoshi Shimohata, Jun Nishihira, Masuko Kobori, Toshiyuki Nakagawa
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18401- (2023)
Depression in later life is associated with dementia. Changes in motivated behavior are an important mechanism contributing to dysfunctional cognitive control in depression. Although continuous intake of quercetin-rich onion suppresses cognitive decl
Externí odkaz:
https://doaj.org/article/29b4198e8ca04ead83d58d549f6f12df
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Adult hippocampal neurogenesis (AHN) plays an important role in hippocampus-dependent function. The number of doublecortin (Dcx)-positive immature neurons in the dentate gyrus decreases over time, especially in the early stages of Alzheimer
Externí odkaz:
https://doaj.org/article/d2491e9d86dc45b7a6c9903974d2d38c
Autor:
Eri Ohta, Masanori Itoh, Masashi Ueda, Yoko Hida, Miao-Xing Wang, Miki Hayakawa-Ogura, Shimo Li, Emika Nishida, Kazunori Ohta, Tana, Saiful Islam, Kiyomi Nakagawa, Tomomi Sunayama, Huayue Chen, So Hirata, Masashi Endo, Yoya Ohno, Toshiyuki Nakagawa
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
Apoptotic protease-activating factor 1 (Apaf-1) is a component of apoptosome, which regulates caspase-9 activity. In addition to apoptosis, Apaf-1 plays critical roles in the intra-S-phase checkpoint; therefore, impaired expression of Apaf-1 has been
Externí odkaz:
https://doaj.org/article/5eb083a2c86b476d9a93a91c7bdcf482
Autor:
Toshiyuki Nakagawa, Kazunori Ohta
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2761 (2019)
The initiation of protein synthesis is suppressed under several stress conditions, inducing phosphorylation of the α-subunit of the eukaryotic initiation factor 2 (eIF2α), thereby inactivating the GTP-GDP recycling protein eIF2B. By contrast, the m
Externí odkaz:
https://doaj.org/article/31f0c7872edb4633bbc026da05effede
Publikováno v:
Biochemical and Biophysical Research Communications. 654:112-119
Autor:
null Tana, Toshiyuki Nakagawa
Publikováno v:
Biochemical and biophysical research communications. 588
Alzheimer's disease (AD) is the most common cause of dementia in the elderly population. Inflammation plays an important role in AD, as microglia respond to several pathological insults, such as Aβ, and exert protective homeostatic functions (anti-i
Autor:
Emika Nishida, Dong-soo Lee, Saiful Islam, Miao-xing Wang, Toshiyuki Nakagawa, Masanori Itoh, Masatake Osawa, Masashi Ueda, Tana, Kiyomi Nakagawa
Publikováno v:
Brain Research. 1688:81-90
Olfaxin, which is a BNIP2 and Cdc42GAP homology (BCH) domain-containing protein, is predominantly expressed in mitral and tufted (M/T) cells in the olfactory bulb (OB). Olfaxin and Caytaxin, which share 56.3% amino acid identity, are similar in their
Autor:
Jun Nishihira, Toshiyuki Nakagawa, Yuji Sato, Mie Nishimura, Tatsuya Ohkawara, Masuko Kobori, Takato Muro, Hiroki Satoh
Publikováno v:
SC40201804180020
NARO成果DBd
書誌情報のみ
Functional Foods in Health and Disease, Vol 7, Iss 6, Pp 353-374 (2017)
NARO成果DBd
書誌情報のみ
Functional Foods in Health and Disease, Vol 7, Iss 6, Pp 353-374 (2017)
Background: Quercetin, a phenolic compound, exhibits various functional effectsthat includeanti-oxidant, anti-dyslipidemic, and anti-dysglycemic activities, in addition tobeneficial effects on cognitive function. We evaluated the effects of a powder
Autor:
Toshiyuki Nakagawa, Tomomi Sunayama, Emika Nishida, Shimo Li, Masashi Endo, Saiful Islam, Huayue Chen, Kazunori Ohta, Eri Ohta, So Hirata, Miao-xing Wang, Miki Hayakawa-Ogura, Masanori Itoh, Yoko Hida, Masashi Ueda, Kiyomi Nakagawa, Tana, Yoya Ohno
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
Apoptotic protease-activating factor 1 (Apaf-1) is a component of apoptosome, which regulates caspase-9 activity. In addition to apoptosis, Apaf-1 plays critical roles in the intra-S-phase checkpoint; therefore, impaired expression of Apaf-1 has been
Autor:
Shimo Li, Emika Nishida, Masashi Ueda, Hiroshi Akanabe, Saiful Islam, Kiyomi Nakagawa, Daisuke Yanagida, Takato Muro, Miki Hayakawa, Ryo Nakabayashi, Takashi Inuzuka, Yoshinori Itoh, Kazunori Ohta, Kazuki Saito, Tetsuya Mori, Tokio Chikaishi, Masanori T. Itoh, Kaori Ohzawa, Tana, Chihiro Suzuki, Yasushi Yamada, Masuko Kobori, Miao-xing Wang, Toshiyuki Nakagawa, Yuichi Hayashi
Publikováno v:
SC30201706210018
Patients with Alzheimer's disease (AD) experience a wide array of cognitive deficits, which typically include the impairment of explicit memory. In previous studies, the authors reported that a flavonoid, quercetin, reduces the expression of ATF4 and