Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Toshiyuki Kan"'
Publikováno v:
Cells, Vol 13, Iss 5, p 387 (2024)
Staphylococcus aureus, a bacterium found on human skin, produces toxins and various virulence factors that can lead to skin infections such as atopic dermatitis. These toxins and virulence factors are carried in membrane vesicles (MVs), composed of t
Externí odkaz:
https://doaj.org/article/7b446e05759e41d5aa34e765b6675a5c
Publikováno v:
Microorganisms, Vol 11, Iss 4, p 1039 (2023)
Patients with diabetes are known to be more susceptible to infections following the establishment of Staphylococcus aureus in their nasal passages and on their skin. The present study evaluated the effects of staphylococcal enterotoxin A (SEA) on the
Externí odkaz:
https://doaj.org/article/7f8ed5d400784e99ade9f3921a91cfe3
Autor:
Tadashi Hattori, Hiroki Tagawa, Makoto Inai, Toshiyuki Kan, Shin-ichiro Kimura, Shigeru Itai, Samir Mitragotri, Yasunori Iwao
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Nobiletin (NOB), a flavonoid, has extremely low water solubility and low oral bioavailability; however, despite these problems, various physiological effects have been investigated in vitro. In the present study, we investigated the transder
Externí odkaz:
https://doaj.org/article/63fa0dea7c1444fd9daa6d6a0abd59dc
Autor:
Yuko Shimamura, Rina Noaki, Ami Kurokawa, Mio Utsumi, Chikako Hirai, Toshiyuki Kan, Shuichi Masuda
Publikováno v:
Toxins, Vol 13, Iss 9, p 609 (2021)
Staphylococcal enterotoxin A (SEA), which is a superantigen toxin protein, binds to cytokine receptor gp130. Gp130 activates intracellular signaling pathways, including the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pa
Externí odkaz:
https://doaj.org/article/414c817d55c944099ae61871bacedfed
Autor:
Miki Takii, Yukiko K. Kaneko, Kiriko Akiyama, Yuki Aoyagi, Yuki Tara, Tomohiro Asakawa, Makoto Inai, Toshiyuki Kan, Kiyomitsu Nemoto, Tomohisa Ishikawa
Publikováno v:
Journal of Functional Foods, Vol 30, Iss , Pp 8-15 (2017)
To determine the mechanism underlying anti-diabetic effects of nobiletin, a citrus flavonoid, the effects of nobiletin on insulin secretion and β-cell apoptosis were investigated in the INS-1D β-cell line. Nobiletin increased glucose-induced insuli
Externí odkaz:
https://doaj.org/article/91b3ad4fe08049fdb9a19d4f12a61850
Autor:
Yuko Shimamura, Mio Utsumi, Chikako Hirai, Ami Kurokawa, Toshiyuki Kan, Norio Ohashi, Shuichi Masuda
Publikováno v:
Molecules, Vol 25, Iss 8, p 1867 (2020)
Staphylococcal enterotoxin A (SEA) functions both as superantigens that stimulate non-specific T cell proliferation as well as potent gastrointestinal toxins. We previously reported that (−)-epigallocatechin gallate (EGCG) binds to SEA. Therefore,
Externí odkaz:
https://doaj.org/article/3286b68e4e4f414fb7a7344747780bec
Autor:
Yuko Shimamura, Mio Utsumi, Chikako Hirai, Shogo Nakano, Sohei Ito, Ai Tsuji, Takeshi Ishii, Takahiro Hosoya, Toshiyuki Kan, Norio Ohashi, Shuichi Masuda
Publikováno v:
Molecules, Vol 23, Iss 5, p 1125 (2018)
Staphylococcal enterotoxin A (SEA) is a toxin protein, and is the most common cause of staphylococcal food poisoning. Polyphenols, such as catechins, are known to interact with proteins. In this study, we investigated the binding of catechins to SEA
Externí odkaz:
https://doaj.org/article/d3278c4377f84c409997d3b531f3bf7a
Autor:
Kosuke Shimizu, Tomohiro Asakawa, Norihiro Harada, Dai Fukumoto, Hideo Tsukada, Tomohiro Asai, Shizuo Yamada, Toshiyuki Kan, Naoto Oku
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e85520 (2014)
The aim of this study was to achieve real-time imaging of the in vivo behavior of a green tea polyphenol, catechin, by positron emission tomography (PET). Positron-labeled 4″ -[(11)C]methyl-epigallocatechin gallate ([(11)C]Me-EGCG) was orally admin
Externí odkaz:
https://doaj.org/article/2cfb9acdab194b78a86cfdbd3db268b4
Publikováno v:
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi). 64:89-93
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ea8a362f144818577e91de42968ff34
https://doi.org/10.3358/shokueishi.64.89
https://doi.org/10.3358/shokueishi.64.89
Publikováno v:
Recent Advances in Polyphenol Research. :51-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39cc242572d4a132abb5ee12f755adf
https://doi.org/10.1002/9781119844792.ch2
https://doi.org/10.1002/9781119844792.ch2