Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Toshiyasu Matsuo"'
Autor:
Michael O. Frederick, Rachel N. Richey, Douglas Patton Kjell, Gregg Alan Tharp, Taichiro Touge, Michio Kida, Naota Yokoyama, Mark A. Pietz, Toshiyasu Matsuo
Publikováno v:
Organic Process Research & Development. 21:1447-1451
The development of a route for a key building block in the synthesis of abemaciclib is described. The route proceeds through a Leuckart–Wallach reductive amination in flow followed by an Ullmann amination with aqueous ammonia. Key to the Leuckart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143b6df7f109cdde9c5ffda7fce9073b
https://doi.org/10.1021/acs.oprd.7b00234
https://doi.org/10.1021/acs.oprd.7b00234
Autor:
Frederick, Michael O., Pietz, Mark A., Kjell, Douglas P., Richey, Rachel N., Tharp, Gregg A., Taichiro Touge, Naota Yokoyama, Michio Kida, Toshiyasu Matsuo
Publikováno v:
Organic Process Research & Development; Sep2017, Vol. 21 Issue 9, p1447-1451, 5p
Autor:
Masaru Yamazaki, Hideya Yaginuma, Toshiyasu Matsuo, Kazuyoshi Kubo, Hajime Shimazu, Soichi Itoh, Akira Kamada, Yutaka Kohno
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:3302-3309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1941ce94bd303461d33357df1fe7fb3
https://doi.org/10.1248/cpb.30.3302
https://doi.org/10.1248/cpb.30.3302
Publikováno v:
YAKUGAKU ZASSHI. 99:1091-1101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af3d926aed5f4db654e8d6864ec486b9
https://doi.org/10.1248/yakushi1947.99.11_1091
https://doi.org/10.1248/yakushi1947.99.11_1091
Publikováno v:
Chemical and Pharmaceutical Bulletin. 17:495-498
Wilzbach tritiation in ortho-, meta- and para-aminobenzoic acids was compared with acid catalysed hydrogen exchange reaction and bromination. The acid catalysed hydrogen exchange reaction of the acids in 4 N DCl occurred at ortho and para to amino gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::821fe656f12c21c0c6cc19f5e3a83b1e
https://doi.org/10.1248/cpb.17.495
https://doi.org/10.1248/cpb.17.495
Publikováno v:
Chemical and Pharmaceutical Bulletin. 20:990-993
Platinum catalyzed hydrogen exchange reaction of ortho, meta, and para aminobenzoate with deuterium oxide was studied. Deuterium analysis was carried out by nuclea magnetic resonance (NMR) spectrometry and the NMR spectra of aminobenzoic acids and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1dd6d66c570566f7287b6118fd6e6a5
https://doi.org/10.1248/cpb.20.990
https://doi.org/10.1248/cpb.20.990
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:1030-1032
Two novel fused ring systems made up of 1, 4-thiazine and 3 (2H)-pyridazinone were synthesized. 3, 4-Dihydro-7-methyl-2H-pyridazino [4, 5-b]-1, 4-thiazin-8 (7H)-one was obobtained from the intramolecular cyclization of 4-chloro-5-(2-chloroethylamino)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f950335492b771e233af4246f8493a
https://doi.org/10.1248/cpb.30.1030
https://doi.org/10.1248/cpb.30.1030
Publikováno v:
Chemischer Informationsdienst. 13
4-Chloro-5-(2-hydroxyethylamino)-3 (2H)-pyridazinones were converted upon treatment with base to novel fused ring compounds, 3, 4-dihydro-2H-pyridazino [4, 5-b]-1, 4-oxazin-8 (7H)-ones. When a nitrogen atom in the hydroxyethylamino group or at the 2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84e24028892e102284d59a9f6beef20b
https://doi.org/10.1002/chin.198236199
https://doi.org/10.1002/chin.198236199
Publikováno v:
Chemischer Informationsdienst. 13
Two novel fused ring systems made up of 1, 4-thiazine and 3 (2H)-pyridazinone were synthesized. 3, 4-Dihydro-7-methyl-2H-pyridazino [4, 5-b]-1, 4-thiazin-8 (7H)-one was obobtained from the intramolecular cyclization of 4-chloro-5-(2-chloroethylamino)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840a13ca9311965ac1e5aeb5224a861b
https://doi.org/10.1002/chin.198236200
https://doi.org/10.1002/chin.198236200