Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Toshiyasu Ishioka"'
Autor:
Mikihiko Naito, Ryohei Katayama, Naoya Fujita, Toshiyasu Ishioka, Ritsuko Takada, Takashi Tsuruo, Shinji Takada
Publikováno v:
Journal of Cell Science. 123:23-28
Cellular FLIP (cFLIP) inhibits the apoptosis signaling initiated by death receptor ligation. We previously reported that a long form of cFLIP (cFLIP-L) enhances Wnt signaling via inhibition of β-catenin ubiquitylation. In this report, we present evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf549b2b2e51a243bd827f82a72b4c34
https://doi.org/10.1242/jcs.058602
https://doi.org/10.1242/jcs.058602
Autor:
Masahiro Nanjo, Mikihiko Naito, Ryohei Katayama, John C. Reed, Masatoshi Kitagawa, Takashi Tsuruo, Toshiyasu Ishioka, Ritsuko Takada, Shinji Takada, Shu-ichi Matsuzawa, Kohei Takubo, Masanori Taira, Chizuko Hashimoto, Akiko Suga
Publikováno v:
Molecular and Cellular Biology. 24:8418-8427
Cellular FLIP (cFLIP) is a close homologue of caspase 8 without caspase activity that inhibits Fas signaling. The cFLIP protein is often expressed in human tumors and is believed to suppress antitumor immune responses involving the Fas system. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db386d1a16b03ebf15cdf7d567afaef1
https://doi.org/10.1128/mcb.24.19.8418-8427.2004
https://doi.org/10.1128/mcb.24.19.8418-8427.2004
Autor:
Hirokazu Ohata, Ryohei Katayama, Keiko Sekine, Chizuko Hashimoto, Yanyan Hao, Hitoshi Nakamura, Atsushi Kawabata, Mikihiko Naito, Takashi Tsuruo, Toshiyasu Ishioka, Tetsuo Noda, Xiaodong Zhang
Publikováno v:
Nature Cell Biology. 6:849-860
Apollon (also known as BRUCE or BIRC6) is a large protein containing baculoviral-IAP-repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domains at the amino- and carboxy termini, respectively. Apollon inhibits apoptosis, but its molecular and physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a2f28227ae760ad169af02b6ffc830
https://doi.org/10.1038/ncb1159
https://doi.org/10.1038/ncb1159
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2655-2658
Anti-androgens were designed based on the principle of inhibiting the folding of helix 12 of the nuclear androgen receptor. The prepared anti-androgens exhibited full antagonistic activity toward human prostate tumor LNCaP cells with T877A point-muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca5a0df2b65dac04c121bde1523f2d7
https://doi.org/10.1016/s0960-894x(03)00575-4
https://doi.org/10.1016/s0960-894x(03)00575-4
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:1555-1566
3-Substituted (Z)-4-(4-N,N-dialkylaminophenylmethylene)-5(4H)-isoxazolones and related compounds were designed and prepared as candidates for structurally novel androgen antagonists. Several compounds showed potent anti-androgenic activity as assesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d34dd48752003da81cdf13d3a85e33
https://doi.org/10.1016/s0968-0896(01)00421-7
https://doi.org/10.1016/s0968-0896(01)00421-7
Publikováno v:
Biological and Pharmaceutical Bulletin. 23:1387-1390
Substituted phenylazo and phenylazoxy compounds were systematically prepared and their anti-androgenic activity was measured in terms of (1) the growth-inhibiting effect on an androgen-dependent cell line, SC-3, and (2) the binding affinity to nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec8fa0e0b1a05da721333138ff4ebb7
https://doi.org/10.1248/bpb.23.1387
https://doi.org/10.1248/bpb.23.1387
Publikováno v:
ChemInform. 33
3-Substituted (Z)-4-(4-N,N-dialkylaminophenylmethylene)-5(4H)-isoxazolones and related compounds were designed and prepared as candidates for structurally novel androgen antagonists. Several compounds showed potent anti-androgenic activity as assesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97feffc2a1d2b473e81101461ce35bb9
https://doi.org/10.1002/chin.200221144
https://doi.org/10.1002/chin.200221144
Autor:
Michie Nishimoto, Takashi Tsuruo, John C. Reed, Toshiyasu Ishioka, Ritsuko Takada, Shu-ichi Matsuzawa, Ryo Kikuchi, Mikihiko Naito, Ryohei Katayama, Shinji Takada
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 12(6)
Cellular FLIP (cFLIP) is a homologue of caspase-8 without protease activity that inhibits the apoptosis signaling initiated by death receptor ligation. We previously reported that a long form of cFLIP (cFLIP-L) inhibits ubiquitylation of beta-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea962b184ce05835f62376dc2c2ecd0a
https://pubmed.ncbi.nlm.nih.gov/17573774
https://pubmed.ncbi.nlm.nih.gov/17573774