Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Toshiya TAKIGAWA"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113333 (2014)
The surfaces of oral mucosa are protected from infections by antimicrobial proteins and natural immunoglobulins that are constantly secreted in saliva, serving as principal innate immune defense in the oral cavity. MyD88 is an important adaptor prote
Externí odkaz:
https://doaj.org/article/7c3d3af820a049d8a013f8c0ffce3049
Autor:
Akiko Sugiyama, Toshiya Takigawa
Publikováno v:
Journal of oral biosciences. 62(3)
Objectives Cleft palate is a frequent congenital craniofacial malformation of unknown etiology. Transforming growth factor (TGF) β3 is required for palatal shelf fusion. Although TGFβ3 knockout (KO) mice are widely used mouse models for cleft palat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc79976720d5f7d9b90a89ccb767138
https://pubmed.ncbi.nlm.nih.gov/32603777
https://pubmed.ncbi.nlm.nih.gov/32603777
Publikováno v:
Cellular Signalling. 24:1150-1162
Toll-like receptors (TLRs) serve as the major innate immune sensors for detection of specific molecular patterns on various pathogens. TLRs activate signaling events mainly by utilizing ubiquitin-dependent mechanisms. Recent research advances have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72e3c9725e46fb3cb4b0b66d772176d
https://doi.org/10.1016/j.cellsig.2012.01.020
https://doi.org/10.1016/j.cellsig.2012.01.020
Autor:
Toshiya Takigawa, Kohei Shiota
Publikováno v:
The International Journal of Developmental Biology. 48:307-317
During fusion of the mammalian secondary palate, it has been suggested that palatal medial edge epithelial (MEE) cells disappear by means of apoptosis, epithelial-mesenchymal transformation (EMT) and epithelial cell migration. However, it is widely b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4117d18e8dba17c6dd091030305aa00
https://doi.org/10.1387/ijdb.041840tt
https://doi.org/10.1387/ijdb.041840tt
Autor:
R.Yoshiyuki OSAMURA, Kiyotsugu KOJIMA, Akishi Ooi, Yoichi Tani, Hiroshi TAKAMI, Takeshi Suzuki, Kuniaki Takata, Yoshihiro Akimoto, Hiroshi Hirano, Jun NAKAYAMA, Tsutomu KATSUYAMA, Minoru FUKUDA, Kaneyuki KUBUSHIRO, Hiroshi YAMASHITA, Katsumi TSUKAZAKI, Shiro NOZAWA, Kiyoshi FURUKAWA, Tokuhiro Ishihara, Yoshinobu Hoshii, Yutaka TSUTSUMI, Nobuyuki SUSUMU, Hitoshi TSUDA, Daisuke AOKI, Shin-ichi KOMIYAMA, Yasuhiro UDAGAWA, Setsuo HIROHASHI, Masaki IWAI, Akira MURAMATSU, Kei KASHIMA, Hiroko Matsushita, Yoshihiro Takeuchi, Yoshinori OTSUKI, Masayuki Miura, Toshiya TAKIGAWA, Kohei SHIOTA, Kazuo NAGASHIMA, Yasuo UCHIYAMA, Shoichi SHIMADA, Shinya UGAWA, Masaki Tanaka, Stephen M. Strittmatter, Yoshinari AIMI, Ikuo TOOYAMA, Osamu YASUHARA, Hiroshi KIMURA, Yasuhito Shirai, Naoaki Saito, Takeshi Kaneko, Takahiro Furuta, Toshimichi YOSHIDA, Kyoko IMANAKA-YOSHIDA, Haruo Ohtani, Yoshihisa UMEKITA, Yukio Takeshima, Kouki Inai
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 32:502-516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9b03bf3677b5e8c13819a114d37938
https://doi.org/10.1267/ahc.32.502
https://doi.org/10.1267/ahc.32.502
Publikováno v:
The Anatomical Record. 242:103-110
Background: Programmed cell death is an essential event during mammalian morphogenesis which eliminates unnecessary cells to accomplish histogenesis and organogenesis. Cell death in interdigital spaces of the developing limb is a classical example of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684e8a244b0445b62b12ddbeae632365
https://doi.org/10.1002/ar.1092420114
https://doi.org/10.1002/ar.1092420114
Publikováno v:
Japanese Journal of Oral & Maxillofacial Surgery. 38:863-871
Although many investigations for pathogenesis of temporomandibular joint (TMJ) disorders have been made by biochemical and histochemical methods, it has not been elucidated completely.In the present study, a preliminary examination was made concernin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc70929283135c56deaf5b9c1dea1b1
https://doi.org/10.5794/jjoms.38.863
https://doi.org/10.5794/jjoms.38.863
Autor:
Mutsuko Minata, Kouji H. Harada, Kouhei Shiota, Toshiya Takigawa, Norimitsu Saito, Megumi Toyoshima, Akio Koizumi, Kayoko Inoue, Saho Era
Publikováno v:
Toxicology. 256(1-2)
Perfluorooctane sulfonate (PFOS) is found ubiquitously in the environment, and is known to cause developmental toxicity, including cleft plate (CP). The aim of the present study was to elucidate the mechanism of CP associated with in utero exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7955a51855e3d0352c6e49acee8c1160
https://pubmed.ncbi.nlm.nih.gov/19041924
https://pubmed.ncbi.nlm.nih.gov/19041924
Autor:
Daisuke Higashiyama, Makoto Ishibashi, Munekazu Komada, Toshiya Takigawa, Kohei Shiota, Hirotomo Saitsu
Publikováno v:
Birth defects research. Part A, Clinical and molecular teratology. 79(7)
BACKGROUND: Prenatal exposure to ethanol induces holoprosencephalic malformations in both humans and laboratory animals. However, its teratogenic window for inducing holoprosencephaly is narrow, and the teratogenic mechanism is not well understood. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68384d9de4dafa48d74c421e0081da2d
https://pubmed.ncbi.nlm.nih.gov/17393481
https://pubmed.ncbi.nlm.nih.gov/17393481
Publikováno v:
The International journal of developmental biology. 49(1)
The inner ear structures are derived from the otic vesicle (OV) which is formed by thickening and invagination of the otic placode of the surface ectoderm. A number of neuroblasts, which arise from epithelial cells of the otic vesicle, delaminate and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad249e78c2d26402f979af77071b587a
https://pubmed.ncbi.nlm.nih.gov/15744664
https://pubmed.ncbi.nlm.nih.gov/15744664