Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Toshiya Sato"'
Autor:
Yoshiki Fujii, Takeshi Tsugawa, Yuya Fukuda, Shuhei Adachi, Saho Honjo, Yusuke Akane, Kenji Kondo, Yoshiyuki Sakai, Toju Tanaka, Toshiya Sato, Yoshihito Higasidate, Noriaki Kubo, Toshihiko Mori, Shinsuke Kato, Ryo Hamada, Masayoshi Kikuchi, Yasuo Tahara, Kazushige Nagai, Toshio Ohara, Masaki Yoshida, Shuji Nakata, Atsuko Noguchi, Wakako Kikuchi, Hiromichi Hamada, Shoko Tokutake-Hirose, Makoto Fujimori, Masamichi Muramatsu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
In the 2010s, several unusual rotavirus strains emerged, causing epidemics worldwide. This study reports a comprehensive molecular epidemiological study of rotaviruses in Japan based on full-genome analysis. From 2014 to 2019, a total of 489 rotaviru
Externí odkaz:
https://doaj.org/article/7ee01ff0a4ae47e7aa634340d86adc51
Autor:
Yoshiko Nakagawa-Nagahama, Masaki Igarashi, Masaomi Miura, Kosuke Kashiwabara, Keisuke Yaku, Yuichiro Fukamizu, Toshiya Sato, Takanobu Sakurai, Takashi Nakagawa, Takashi Kadowaki, Toshimasa Yamauchi
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Age-related hearing loss (ARHL) is a common phenomenon observed during aging. On the other hand, the decrease in Nicotinamide adenine dinucleotide (NAD +) levels is reported to be closely related to the age-related declines in phy
Externí odkaz:
https://doaj.org/article/9014483caae543e68adedcdbc73a2f9d
Autor:
Toshiya Sato, Kanako Oda, Seiko Sakai, Rika Kato, Saori Yamamori, Makoto Itakura, Yoshio Kodera, Masatoyo Nishizawa, Toshikuni Sasaoka, Osamu Onodera, Minesuke Yokoyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract TAR DNA-binding protein 43 kDa (TDP-43), a nuclear protein, plays an important role in the molecular pathogenesis of amyotrophic lateral sclerosis (ALS). The long-disordered C-terminal region (CTR) of TDP-43 is known to be aggregation-prone
Externí odkaz:
https://doaj.org/article/419759e22ee04f0e92a2be83c4e71e34
Autor:
Yuichiro Fukamizu, Yoshiaki Uchida, Akari Shigekawa, Toshiya Sato, Hisayuki Kosaka, Takanobu Sakurai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract A decrease in the intracellular level of nicotinamide adenine dinucleotide (NAD+), an essential coenzyme for metabolic activity, causes various age-related diseases and metabolic abnormalities. Both in-vivo and in-vitro studies have shown th
Externí odkaz:
https://doaj.org/article/efb7a2f69b3b4163bfa46d7d4232e742
Autor:
Keisuke Okabe, Keisuke Yaku, Yoshiaki Uchida, Yuichiro Fukamizu, Toshiya Sato, Takanobu Sakurai, Kazuyuki Tobe, Takashi Nakagawa
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Nicotinamide mononucleotide (NNM) is an orally bioavailable NAD+ precursor that has demonstrated beneficial effects against aging and aging-associated diseases in animal models. NMN is ultimately converted to NAD+, a redox cofactor that mediates many
Externí odkaz:
https://doaj.org/article/d84f9a702e154b398b0875e024b1ed62
Autor:
Atsushige Ashimori, Yasukazu Nakahata, Toshiya Sato, Yuichiro Fukamizu, Takaaki Matsui, Hikari Yoshitane, Yoshitaka Fukada, Kazuyuki Shinohara, Yasumasa Bessho
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The circadian clock possesses robust systems to maintain the rhythm approximately 24 h, from cellular to organismal levels, whereas aging is known to be one of the risk factors linked to the alternation of circadian physiology and behavior. The amoun
Externí odkaz:
https://doaj.org/article/dd6bc72c7aad4ef1aa1fc0a19b545faf
Autor:
Shintaro Saegusa, Masahiro Fukaya, Wataru Kakegawa, Manabu Tanaka, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Tadashi Okubo, Toshiya Sato, Michisuke Yuzaki, Hiroyuki Sakagami
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216960 (2019)
ADP ribosylation factor 6 (Arf6) is a small GTPase that regulates various neuronal events including formation of the axon, dendrites and dendritic spines, and synaptic plasticity through actin cytoskeleton remodeling and endosomal trafficking. EFA6C,
Externí odkaz:
https://doaj.org/article/4c0abf6b9e874d7b91bbbfce6a46dbe6
Autor:
Yasushi Ota, Yoshihiro Ikemiyagi, Toshiya Sato, Tatsuo Funakoshi, Nobuyuki Hiruta, Makoto Kitamura, Hideaki Bujo, Mitsuya Suzuki
Publikováno v:
Allergology International, Vol 65, Iss 4, Pp 396-399 (2016)
Background: Studies show that immunoglobulin E (IgE) is produced in the local nasal mucosa in allergic rhinitis patients. However, no study involved the measurement of IgE levels in the local nasal mucosal tissue in allergic rhinitis patients. This s
Externí odkaz:
https://doaj.org/article/8a57bd97cb244c52a7db840d265b6f1b
Autor:
Yasushi Ota, Fumio Ishikawa, Toshiya Sato, Nobuyuki Hiruta, Makoto Kitamura, Hiromitsu Yokota, Yoshihiro Ikemiyagi, Hideaki Bujo, Mutsunori Fujiwara, Mitsuya Suzuki
Publikováno v:
Allergology International, Vol 66, Iss 4, Pp 634-636 (2017)
Externí odkaz:
https://doaj.org/article/51c8fc9b74b04cd5b6f966edd3dff8f8
Autor:
Visesato Mor, Amir M Farnoud, Ashutosh Singh, Antonella Rella, Hiromasa Tanno, Keiko Ishii, Kazuyoshi Kawakami, Toshiya Sato, Maurizio Del Poeta
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153853 (2016)
Cryptococcus neoformans is an opportunistic fungal pathogen and the causative agent of the disease cryptococcosis. Cryptococcosis is initiated as a pulmonary infection and in conditions of immune deficiency disseminates to the blood stream and centra
Externí odkaz:
https://doaj.org/article/adcfa3f9872d46388f4d3a4c51a0b7f7