Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Toshiya Okamura"'
Autor:
Hiromu Okano1,2, Toshiya Okamura3, Yasunori Takahashi1,2, Kazumi Takashima1,2, Ryota Ojiro1,2, Qian Tang1,2, Meilan Jin4, Satomi Kikuchi1,2, Bunichiro Ogawa1, Toshinori Yoshida1,2, Tomoya Yoshinari5, Makoto Shibutani1,2,6 mshibuta@cc.tuat.ac.jp
Publikováno v:
Journal of Toxicological Sciences. 2021, Vol. 46 Issue 4, p157-165. 9p.
Autor:
Satomi Kikuchi, Qian Tang, Toshiya Okamura, Kazumi Takashima, Makoto Shibutani, Hiromu Okano, Bunichiro Ogawa, Toshinori Yoshida, Ryota Ojiro, Meilan Jin, Yasunori Takahashi, Tomoya Yoshinari
Publikováno v:
The Journal of toxicological sciences. 46(4)
Enniatins are so-called "emerging mycotoxins" that commonly occur in milligrams per kilogram levels in grains and their derived products, as well as in fish, dried fruits, nuts, spices, cocoa, and coffee. The present study investigated the 28-day rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def3e31222c9f5f3f8fe993990a3da31
https://pubmed.ncbi.nlm.nih.gov/33814509
https://pubmed.ncbi.nlm.nih.gov/33814509
Autor:
Koji Morishita, Mami Aoki, Atsushi Nakamura, Masahiro Mochizuki, Kazuhisa Hatayama, Toshiya Okamura
Publikováno v:
Fundamental Toxicological Sciences. 1:63-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c74c47cafe3cd0263e22eae3a2b82e6
https://doi.org/10.2131/fts.1.63
https://doi.org/10.2131/fts.1.63
Autor:
Takashi Umemura, Kumiko Ogawa, Tomoki Inoue, Toshiya Okamura, Shigehisa Okamoto, Masako Tasaki, Yasushi Nakamura, Eun Young Park, Akiyoshi Nishikawa, Yuji Ishii, Tomoaki Matsuo, Kenji Sato
Publikováno v:
Journal of Agricultural and Food Chemistry. 61:2103-2108
The modifying effects of 4-methylthio-3-butenyl isothiocyanate (MTBITC) and curcumin were investigated in N-nitrosobis(2-oxopropyl)amine (BOP)-initiated hamsters. Male 6-week-old Syrian hamsters were subcutaneously injected with 10 mg/kg body weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4aaf9632224d35f1d072b6aff48c6b
https://doi.org/10.1021/jf3003174
https://doi.org/10.1021/jf3003174
Autor:
Tatsuya Ogawa, Toshiya Okamura, Kazutoshi Tamura, Masahiro Mochizuki, Shuzo Okazaki, Osamu Kusuoka, Junichi Kobayashi, Toru Hoshiya, Kazuhisa Hatayama, Saori Suzuki
Publikováno v:
Journal of Toxicologic Pathology
Recently, RccHan(TM):WIST (Wistar Hannover) rats were introduced to toxicity studies in Japan. The present study was performed to obtain control data for general toxicological parameters as an aid for interpretation of results in toxicity studies usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126493fe043bb24dec6fe52c682d9a83
https://doi.org/10.1293/tox.24.195
https://doi.org/10.1293/tox.24.195
Autor:
Takashi Umemura, Daisuke Hibi, Yuta Suzuki, Toshiya Okamura, Yuji Ishii, Akiyoshi Nishikawa, Kumiko Ogawa, Masako Tasaki, Meilan Jin, Shigeaki Takami, Tomoki Inoue, Young-Man Cho
Publikováno v:
Journal of Toxicologic Pathology
Carcinosarcomas are rare tumors in humans as well as rats and most commonly occur in the uterus. Recently, we observed a case of incidental carcinosarcoma of the uterus in a female Wistar Hannover GALAS [BrlHan:WIST@ Jcl (GALAS)] rat at 2 years of ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b03489a4a5ef6dfa11a366d632f9b5a
https://doi.org/10.1293/tox.24.63
https://doi.org/10.1293/tox.24.63
Autor:
Takehiko Nohmi, Tomoki Inoue, Yuji Ishii, Soichi Maruyama, Masako Tasaki, Yuta Suzuki, Daisuke Hibi, Takashi Umemura, Toshiya Okamura, Akiyoshi Nishikawa
Publikováno v:
Cancer Science. 101:2525-2530
Previous reports have proposed that reactive oxygen species resulting from induction of cytochrome P450 (CYP) isozymes might be involved in the modes of action of hepatocarcinogens with CYP-inducible potency. In the present study, we investigated 8-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdc199157b83feb154830f0e547c464
https://doi.org/10.1111/j.1349-7006.2010.01705.x
https://doi.org/10.1111/j.1349-7006.2010.01705.x
Publikováno v:
Tetrahedron Letters. 51:5177-5180
An efficient procedure through deprotection of 2,4,6-trimethoxypyrimidine derivative afforded porphyrinato zinc bearing multi-barbiturates acting as multiple hydrogen bonding sites at the meso positions. Addition of excess amphiphilic triaminopyrimid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd8450ef14aa345391d8248e98a43ab
https://doi.org/10.1016/j.tetlet.2010.07.139
https://doi.org/10.1016/j.tetlet.2010.07.139
Autor:
Yuta Suzuki, Akiyoshi Nishikawa, Tomoki Inoue, Yuji Ishii, Masako Tasaki, Yukio Kodama, Kunitoshi Mitsumori, Toshiya Okamura, Takashi Umemura, Takehiko Nohmi
Publikováno v:
The Journal of Toxicological Sciences. 35:709-720
Chronic stimulus subsequent to cell injury plays an important role in cancer development, but the precise mechanisms remain unknown partly because appropriate animal models are lacking. In the present study, the effects of hepatotoxicant carbon tetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0aad2bd521296e2a8e12511a092ffd0
https://doi.org/10.2131/jts.35.709
https://doi.org/10.2131/jts.35.709
Autor:
Yuta Suzuki, Yukio Kodama, Masako Tasaki, Yuji Ishii, Takehiko Nohmi, Toshiya Okamura, Kunitoshi Mitsumori, Tomoki Inoue, Akiyoshi Nishikawa, Takashi Umemura
Publikováno v:
The Journal of Toxicological Sciences. 35:731-741
To investigate the effects of dextran sulfate sodium (DSS) and/or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) on in vivo genotoxicity in the colon, male C57BL/6 p53 (+/+), p53 (+/-) or p53 (-/-) gpt delta mice were twice given 1-week treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121ad31f1440cc3c9a9d0d060bb77e32
https://doi.org/10.2131/jts.35.731
https://doi.org/10.2131/jts.35.731