Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Toshiya Kanaji"'
Autor:
Toshiko Shibata-Nozaki, Hiroshi Ito, Hirofumi Mitomi, Takayuki Maruyama, So Nomoto, Hidehiro Yamada, Tatsuya Komagata, Toshiya Kanaji, Toshihito Mori, Shoichi Ozaki, Jun Akaogi
Publikováno v:
Arthritis & Rheumatism. 63:2595-2605
Objective We recently developed an ex vivo cellular model of pannus, the aberrant overgrowth of human synovial tissue. This study was undertaken to use that model to investigate the role of prostaglandin E2 (PGE2) and its receptor subtypes in the dev
Publikováno v:
Biomedical Research. 18:297-302
Autor:
Takayuki Maruyama, Takashi Nakamura, Yonghui Jin, Shinsei Fujimura, K Ito, Akio Nishiura, Junya Toguchida, Takanobu Otsuka, Hiroto Mitsui, Hikaru Sugihara, Moritoshi Furu, Toshiya Kanaji, Tomoki Aoyama
Publikováno v:
Arthritis Research & Therapy
[Introduction]Osteoarthritis (OA) is a common cause of disability in older adults. We have previously reported that an agonist for subtypes EP2 of the prostaglandin E2 receptor (an EP2 agonist) promotes the regeneration of chondral and osteochondral
Autor:
Toshiyuki Matsuoka, Naoki Terada, Shuh Narumiya, Toshiyuki Kamoto, Atsushi Maeno, Takashi Kobayashi, Takayuki Maruyama, Takahiro Inoue, Toshiya Kanaji, Tomomi Kamba, Osamu Ogawa, Yosuke Shimizu, Yasushi Okuno, Gozoh Tsujimoto, Yoshiki Mikami, Eijiro Nakamura, Yoshinobu Toda
Publikováno v:
Journal of Urology. 183
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft mode
Autor:
Yoshiki Mikami, Eijiro Nakamura, Toshiyuki Matsuoka, Takahiro Inoue, Takashi Kobayashi, Atsushi Maeno, Takayuki Maruyama, Yosuke Shimizu, Gozoh Tsujimoto, Yasushi Okuno, Naoki Terada, Toshiyuki Kamoto, Toshiya Kanaji, Tomomi Kamba, Shuh Narumiya, Yoshinobu Toda, Osamu Ogawa
Publikováno v:
Cancer research. 70(4)
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft mode
Autor:
Tadashi Ikeda, Toshiya Kanaji, Yuhong Huang, Hisashi Sakaguchi, Shyamal C. Bir, Jiro Esaki, Akira Marui, Hideki Tsubota, Ryuzo Sakata, Yoshio Arai
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 73(7)
Background: Although intravenous administration of prostaglandin E1 (PGE1) is commonly used in the treatment of peripheral arterial disease, it rapidly becomes inactivated in the lung. Whether local administration of sustained-release (SR) PGE1 enhan
Autor:
Takanobu Otsuka, Takashi Nakamura, Yoshiki Kohno, Yonghui Jin, Seiji Otsuka, T. Maruyama, Tomoki Aoyama, Akira Nasu, Shinsei Fujimura, Moritoshi Furu, Hikaru Sugihara, K Ito, Kenichi Fukiage, Toshiya Kanaji, Akio Nishiura, Junya Toguchida
Publikováno v:
Osteoarthritis and cartilage. 17(4)
Summary Objective The effect of the prostaglandin E2 (PGE2) signal through prostaglandin E receptor 2 (EP2) receptors on the repair of injured articular cartilage was investigated using a selective agonist for EP2. Methods Chondral and osteochondral
Publikováno v:
Journal of biochemistry. 122(3)
The effects of a novel membrane-penetrable modulator, 2APB (2-aminoethoxy diphenyl borate), on Ins(1,4,5)P3-induced Ca2+ release were examined. 2APB inhibited Ins(1,4,5)P3-induced Ca2+ release from rat cerebellar microsomal preparations without affec