Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Toshiya, Kuno"'
Autor:
Yoshikazu Johmura, Jia Sun, Kyoko Kitagawa, Keiko Nakanishi, Toshiya Kuno, Aya Naiki-Ito, Yumi Sawada, Tomomi Miyamoto, Atsushi Okabe, Hiroyuki Aburatani, ShengFan Li, Ichiro Miyoshi, Satoru Takahashi, Masatoshi Kitagawa, Makoto Nakanishi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Cellular senescence—the permanent cessation of cell proliferation—is a process that can be deregulated in cancer and other aging-related diseases. Here the authors demonstrate that the SCFFbxo22-KDM4A complex plays an essential role during senesc
Externí odkaz:
https://doaj.org/article/a78817db806f42beac081b69b8dcfa12
Autor:
Shuichiro Umemura, Katsuyuki Miyabe, Hiromu Kondo, Toshiya Kuno, Michihiro Yoshida, Takahiro Nakazawa, Shuya Shimizu, Itaru Naitoh, Takashi Joh, Kazuki Hayashi, Satoru Takahashi, Akihisa Kato, Hirotaka Ohara, Yasuki Hori, Yuji Nishi
Publikováno v:
Journal of Digestive Diseases. 17:44-51
Objective The diagnostic yields of endoscopic transpapillary brush cytology and forceps biopsies for malignant biliary strictures (MBS) remain unclear and predictive factors for diagnosis have not been established. We aimed to clarify the diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab8f99c8970905287cb8b1d8501924e2
https://doi.org/10.1111/1751-2980.12311
https://doi.org/10.1111/1751-2980.12311
Autor:
Akihisa Kato, Takahiro Nakazawa, Hirotaka Ohara, Shuya Shimizu, Hiromu Kondo, Toshiya Kuno, Itaru Naitoh, Michihiro Yoshida, Yasuki Hori, Kazuki Hayashi, Takashi Joh, Katsuyuki Miyabe, Shuichiro Umemura, Yuji Nishi, Satoru Takahashi
Publikováno v:
Internal Medicine. 55:1575-1579
We herein report a case of a 56-year-old man with IgG4-related sclerosing cholangitis (IgG4-SC) with no biliary stricture, but with a severely thickened bile duct wall. Contrast-enhanced computed tomography showed diffuse swelling of the pancreas and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c923564d7c4b0cf258afd787f3f4b8
https://doi.org/10.2169/internalmedicine.55.6302
https://doi.org/10.2169/internalmedicine.55.6302
Autor:
TOSHIYA KUNO1 tkuno@med.nagoya-cu.ac.jp, SATORU TAKAHASHI1, HIROYUKI TOMITA2, KENJI HISAMATSU2, AKIRA HARA2, AKIHIRO HIRATA3, HIROSHI KOBAYASHI4, HIDEKI MORI2
Publikováno v:
Oncology Letters. Dec2015, Vol. 10 Issue 6, p3377-3384. 8p.
Autor:
Hiromi Kataoka, Satoru Takahashi, Itaru Naitoh, Go Asano, Naruomi Jinno, Kazuki Hayashi, Michihiro Yoshida, Hiroyuki Kato, Yasuki Hori, Katsuyuki Miyabe, Akihisa Kato, Makoto Natsume, Toshiya Kuno
Publikováno v:
Digestive diseases and sciences. 63(12)
The ability of fluorescence in situ hybridization (FISH) assays in endoscopic transpapillary bile duct biopsy specimens to predict the prognosis of cholangiocarcinoma (CCA) has not been elucidated. We aimed to clarify the association between the resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf394c11cbd17ca685d3c24ec28397ec
https://pubmed.ncbi.nlm.nih.gov/30206756
https://pubmed.ncbi.nlm.nih.gov/30206756
Autor:
Hiroyuki Kato, Katsuyuki Miyabe, Michihiro Yoshida, Takashi Joh, Itaru Naitoh, Hiromu Kondo, Toshiya Kuno, Akihisa Kato, Kazuki Hayashi, Satoru Takahashi
Publikováno v:
Journal of hepato-biliary-pancreatic sciences. 25(3)
Background Fluorescence in situ hybridization (FISH) of cytology specimens has been used to diagnose biliary strictures. However, the usefulness of FISH for differentiating between cholangiocarcinoma (CCA) and IgG4-related sclerosing cholangitis (IgG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a95c9791911694347f7ec51f4aca8f
https://pubmed.ncbi.nlm.nih.gov/29532638
https://pubmed.ncbi.nlm.nih.gov/29532638
Autor:
Takahiro Nakazawa, Hiromu Kondo, Itaru Naitoh, Shuya Shimizu, Hiroyuki Kato, Satoru Takahashi, Takashi Joh, Katsuyuki Miyabe, Toshiya Kuno, Shuichiro Umemura, Kazuki Hayashi, Masahiro Tsutsumi, Toshio Mori, Aya Naiki-Ito, Yuji Nishi, Akihisa Kato, Hirotaka Ohara, Michihiro Yoshida, Yasuki Hori, Shugo Suzuki
Publikováno v:
Oncotarget
Despite progress in clinical cancer medicine in multiple fields, the prognosis of pancreatic cancer has remained dismal. Recently, chemopreventive strategies using phytochemicals have gained considerable attention as an alternative in the management
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a6a9ee99d9ba0e386e64131de60282
https://doi.org/10.18632/oncotarget.5981
https://doi.org/10.18632/oncotarget.5981
Autor:
Hideki Mori, Akira Hara, Hiroshi Kobayashi, Toshiya Kuno, Akihiro Hirata, Kenji Hisamatsu, Satoru Takahashi, Hiroyuki Tomita
Publikováno v:
Oncology Letters
Fermented brown rice by Aspergillus oryzae (FBRA) is known to have the potential to prevent chemical carcinogenesis of the colon, liver, esophagus, urinary bladder, stomach and lungs in rodents. The present study examined the possible chemopreventive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c888a947fc6c1ec934be559ac233c8
https://doi.org/10.3892/ol.2015.3809
https://doi.org/10.3892/ol.2015.3809
Autor:
Hirofumi Ohtaki, Masato Hoshi, Hiroyuki Tomita, Yuichiro Hatano, Hiroyasu Ito, Kuniaki Saito, Toshiya Kuno, Manabu Takamatsu, Akihiro Hirata, Mitsuru Seishima, Tatsuya Ando, Akira Hara
Publikováno v:
Cancer Science
Indoleamine 2, 3-dioxygenase (IDO), an enzyme that degrades the essential amino acid L-tryptophan along the kynurenine pathway, exerts immunomodulatory effects in a number of diseases. IDO expression is increased in tumor tissue and in draining lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c0eed69458a9ca7ec6a78f19037625
http://hdl.handle.net/2433/215167
http://hdl.handle.net/2433/215167
Autor:
Yuichiro Hatano, Kyoichi Hashimoto, Toshiya Kuno, Hiroyuki Tomita, Makoto Mark Taketo, Koji Aoki, Manabu Takamatsu, Yasuhiro Yamada, Myeong Sup Lee, Akihiro Hirata, Akira Hara, Katsunori Semi, Young Joon Kim
Publikováno v:
Carcinogenesis. 36:719-729
The forced reduction of global DNA methylation suppresses tumor development in several cancer models in vivo. Nevertheless, the mechanisms underlying these suppressive effects remain unclear. In this report, we describe our findings showing that a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2a217447b4285faeae1017adf6a375
https://doi.org/10.1093/carcin/bgv060
https://doi.org/10.1093/carcin/bgv060