Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Toshitaka Yamaga"'
Autor:
Norio Akaike, Ayaka Hamamoto, Masahito Wakita, Min-Chul Shin, Takatoshi Yamamoto, Toshitaka Yamaga, Kensaku Anraku, Kiku Nonaka
Publikováno v:
Toxins, Vol 5, Iss 1, Pp 193-202 (2013)
The amounts of puffer toxin (tetrodotoxin, TTX) extracted from the fresh and the traditional Japanese salted and fermented “Nukazuke” and “Kasuzuke” ovaries of Takifugu stictonotus (T. stictonotus) were quantitatively analyzed in the voltage-
Externí odkaz:
https://doaj.org/article/923f39bddac8495c8b5e113a6f4258a7
Autor:
Min-Chul Shin, Masahito Wakita, Du-Jie Xie, Toshitaka Yamaga, Satomi Iwata, Yasushi Torii, Tetsuhiro Harakawa, Akihiro Ginnaga, Shunji Kozaki, Norio Akaike
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 1, Pp 33-42 (2012)
Recent studies have demonstrated that the botulinum neurotoxins inhibit the release of acetylcholine, glutamate, GABA, and glycine in central nerve system (CNS) neurons. The Na+ current (INa) is of major interest because it acts as the trigger for ma
Externí odkaz:
https://doaj.org/article/62f5abd3ff5043848867d43c9a9733ca
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 1, Pp 75-81 (2012)
Our recent study showed a possibility that newly developed A2 type botulinum toxin (A2NTX) inhibits both spontaneous and evoked transmitter release from inhibitory (glycinergic or GABAergic) and excitatory (glutamatergic) nerve terminals using rat sp
Externí odkaz:
https://doaj.org/article/f57975b6057445eeb545b6d14c58c105
Publikováno v:
Brain research bulletin. 162
We investigated the effects of nitrous oxide (N2O) on glycinergic inhibitory whole-cell and synaptic responses using a "synapse bouton preparation," dissociated mechanically from rat spinal sacral dorsal commissural nucleus (SDCN) neurons. This techn
Publikováno v:
Journal of Neurophysiology. 120:1264-1273
The current electrophysiological study investigated the functional roles of high- and low-voltage-activated Ca2+ channel subtypes on glutamatergic small mossy fiber nerve terminals (SMFTs) that synapse onto rat hippocampal CA3 neurons. Experiments co
Autor:
Kiku Nonaka, Norio Akaike, Toshitaka Yamaga, Min Chul Shin, Naoki Kotani, Hironari Akaike, Hideaki Nagami
Publikováno v:
The Journal of physiologyReferences. 597(24)
Key points Xenon (Xe) non-competitively inhibited whole-cell excitatory glutamatergic current (IGlu ) and whole-cell currents gated by ionotropic glutamate receptors (IAMPA , IKA , INMDA ), but had no effect on inhibitory GABAergic whole-cell current
Publikováno v:
Brain Research Bulletin. 118:34-45
We evaluated the effects of N2O on synaptic transmission using a preparation of mechanically dissociated rat hippocampal CA3 neurons that allowed assays of single bouton responses evoked from native functional nerve endings. We studied the effects of
Autor:
Norio Akaike, Min Chul Shin, Yuji Mizuno, Toshitaka Yamaga, Megumi Maeda, Masahito Wakita, Kiyomitsu Shoudai, Kiku Nonaka
Publikováno v:
Brain Research Bulletin. 99:19-26
Atrial and brain natriuretic peptides (ANP and BNP) exist in the central nervous system and modulate neuronal function, although the locus of actions and physiological mechanisms are still unclear. In the present study we used rat spinal sacral dorsa
Autor:
Du-Jie Xie, Tetsuhiro Harakawa, Norio Akaike, Satomi Iwata, Yasushi Torii, Shunji Kozaki, Min Chul Shin, Akihiro Ginnaga, Toshitaka Yamaga, Masahito Wakita
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 1, Pp 33-42 (2012)
Recent studies have demonstrated that the botulinum neurotoxins inhibit the release of acetylcholine, glutamate, GABA, and glycine in central nerve system (CNS) neurons. The Na+ current (INa) is of major interest because it acts as the trigger for ma
Autor:
Norio Akaike, Min Chul Shin, Toshitaka Yamaga, Nobuki Murayama, Elena L Kondratskaya, Kiku Nonaka, Megumi Maeda
Publikováno v:
Neurophysiology. 41:250-257
The action of ginkgolide B (GB), a powerful compound of Ginkgo biloba extract, on glycine-mediated spontaneous currents in rat spinal sacral dorsal commissural nucleus (SDCN) neurons was examined. IPSCs evoked in spinal cord slices were inhibited in