Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Toshiro Iwai"'
Publikováno v:
Surgery Today. 38:807-814
Hyperacute rejection (HAR) mediated by the natural antibody (nAb) against Gal alpha 1-3Gal beta-4-GlcNAc (alpha Gal) is the major obstacle in xenogeneic organ transplantation. Previously, we reported the acceptance of donor heart grafts in anti-alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d3df3a75c46877b0cdf5a677bb60f9
https://doi.org/10.1007/s00595-007-3715-1
https://doi.org/10.1007/s00595-007-3715-1
Autor:
Tatsushi Onzuka, Yukihiro Tomita, Yohichi Yasunami, Toshiro Iwai, Yasunobu Yoshikai, Kikuo Nomoto, Ryuji Tominaga, I Shimizu, Takashi Kajiwara, S Okano
Publikováno v:
Transplantation. 84:1686-1695
Background. Recent studies have indicated that natural killer T (NKT) cells are essential for the establishment of transplantation tolerance. In the present study, we have elucidated the role of recipient and donor NKT cells in cyclophosphamide (CP)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9b139f43b08b7845041a4b09754f4e
https://doi.org/10.1097/01.tp.0000295933.94854.d4
https://doi.org/10.1097/01.tp.0000295933.94854.d4
Autor:
Ryuji Tominaga, I Shimizu, Yukihiro Tomita, Takashi Kajiwara, Toshiro Iwai, Tatsushi Onzuka, Shinji Okano
Publikováno v:
Surgery Today. 37:24-29
We previously developed a cyclophosphamide (CP)-induced tolerance protocol, consisting of an intravenous injection of 1 x 10(8) donor spleen cells (SC) given on day 0 and an intraperitoneal injection of 200 mg/kg CP given on day 2. In the present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67263fc367f8972337a1f5fbd8058e9
https://doi.org/10.1007/s00595-006-3329-z
https://doi.org/10.1007/s00595-006-3329-z
Autor:
Ryuji Tominaga, Toshiro Iwai, I Shimizu, Takashi Kajiwara, Yukihiro Tomita, Qi-Wei Zhang, Tatsushi Onzuka, Shinji Okano
Publikováno v:
Scandinavian Journal of Immunology. 64:392-397
The current critical shortage of human donor organs has stimulated the feasibility of the xenogenic transplantation, such as swine to primate. We have previously reported the induction of donor-specific tolerance in MHC-disparated recipient mice by u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0ac94c9708158262749d57082fdd30
https://doi.org/10.1111/j.1365-3083.2006.01831.x
https://doi.org/10.1111/j.1365-3083.2006.01831.x
Autor:
Keijiro Kiyoshima, Toshiro Iwai, Yoriyuki Kamiryo, Masazumi Tsuneyoshi, Katsunori Tatsugami, Masahiko Harano, Masatoshi Eto, Yasunobu Yoshikai, Seiji Naito
Publikováno v:
Cancer Research. 65:10032-10040
Recently, much attention has been paid to nonmyeloablative allogeneic stem cell transplantation for the treatment of metastatic renal cancer. Mature donor T cells cause graft-versus-host disease (GVHD) although they are also the main mediators of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d65cedf0e6b66ece981f2ef45bf26cc
https://doi.org/10.1158/0008-5472.can-05-0457
https://doi.org/10.1158/0008-5472.can-05-0457
Autor:
Toshiro Iwai, Kikuo Nomoto, I Shimizu, Shinji Okano, Katsuo Sueishi, Takashi Kajiwara, Yukihiro Tomita, H. Yasui
Publikováno v:
Scandinavian Journal of Immunology. 62:271-280
In the present study, we have elucidated the efficacy of two cyclophosphamide (CP)-induced tolerance protocols for the induction of B-cell tolerance against Galalpha1-3Galbeta1-4GlcNAc (alphaGal) antigens. alpha1,3-galactosyltransferase-deficient (Ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fbfacbe47f9b0131971776395a5364
https://doi.org/10.1111/j.1365-3083.2005.01644.x
https://doi.org/10.1111/j.1365-3083.2005.01644.x
Autor:
Toshiro Iwai, Goro Matsuzaki, Qi-Wei Zhang, Kikuo Nomoto, Shinji Okano, Hisataka Yasui, Yukihiro Tomita, I Shimizu
Publikováno v:
Surgery Today. 35:364-370
We recently described using cyclophosphamide (CP) plus busulfan (BU) to create drug-induced skin and heart allograft tolerance capable of regularly overcoming fully H-2 mismatched barriers in mice. The present study investigates the intragraft mRNA e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957226153ef01fbcb05d2c0f297b36c5
https://doi.org/10.1007/s00595-004-2963-6
https://doi.org/10.1007/s00595-004-2963-6
Publikováno v:
Transplant International. 17:795-803
By using a cyclophosphamide (CP)-induced tolerance system, we previously raised the possibility that the degree of chimerism might determine the induction of heart and skin allograft tolerance. When C3H (H-2k; Thy1.2, Mls-1b) mice were intravenously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a059941255d1f8cb05ef8c9ad64d8b2
https://doi.org/10.1007/s00147-003-0675-2
https://doi.org/10.1007/s00147-003-0675-2
Autor:
Yasuhisa Oishi, Hisataka Yasui, Ken-ichi Imasaka, Shigeki Morita, Noriyoshi Kajihara, Toshiro Iwai, Munetaka Masuda
Publikováno v:
Japanese Journal of Cardiovascular Surgery. 34:243-247
1997年の臓器移植法施行後,当科で機械的流量補助を必要とした6名において,重症心不全に対する初期の治療戦略を検討した.症例は急性心筋梗塞2例,拡張型心筋症3例,劇症型心筋炎1例.補助
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd79c582e4a1e6f336d69d0b025210b
https://doi.org/10.4326/jjcvs.34.243
https://doi.org/10.4326/jjcvs.34.243
Publikováno v:
KOBUNSHI RONBUNSHU. 62:75-80
繊維含有量44vol%の三次元炭素繊維強化フラン樹脂 (3D-CFRFR) を作製し, 1000℃以下の種々の温度で加熱した. 1000℃の加熱による体積収縮は, フラン樹脂単体で50%であったが, 3D-CFRFRでは数%であ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e01f5f87fa331f379c2e7582257986d9
https://doi.org/10.1295/koron.62.75
https://doi.org/10.1295/koron.62.75